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  1. 1161
  2. 1162
    por Matthews, T. H. J., Lawrence, M. K.
    Publicado 1979
    “…Acute phase serum gave positive results in an interferon assay when collected from 17 out of 45 (38 per cent) patients with proven virus infection, and from none of 43 patients with other disease and none of 61 healthy subjects. …”
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  3. 1163
    por Jordan, L.T., Derbyshire, J.B.
    Publicado 1995
    “…Swine testis (ST) cell cultures were treated with various doses of recombinant human interferon-alpha 2a (IFN), and assayed for 2′,5′ oligoadenylate synthetase (2–5 A synthetase) activity. …”
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  4. 1164
    “…To determine the cellular mechanism of resistance and interferon (IFN)-γ-producing cell populations, mononuclear cells isolated from tissues of the brain were analyzed by the flow cytometry method. …”
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  5. 1165
  6. 1166
  7. 1167
    por Snegaroff, J.
    Publicado 1993
    “…Interferon synthesis by leucocytes from rainbow trout kidney was induced in vitro by contact with various viruses. …”
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  8. 1168
    “…A total of 12 clinically ill cats previously diagnosed as feline infectious peritonitis (FIP) were treated with a combination of recombinant feline interferon and glucocorticoid. A complete remission (over 2 years) and a partial remission (2 to 5 months) were observed in four (33.3%) and four (33.3%) cases, respectively. …”
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  9. 1169
    “…Type-I interferons (IFNs) are cytokines that have non-specific antiviral activity, participating mostly in innate defense mechanisms. …”
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  10. 1170
    “…In the present study, mouse L(B) cells were treated with various concentrations of interferon (IFN) and/or BFA overnight and infected with encephalomyocarditis virus (EMCV) after removal of IFN and BFA. …”
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  11. 1171
    “…In vitro interferon production by peripheral blood mononuclear cells from 50 children suffering from recurrent upper respiratory tract infections was examined, and compared with that of 50 healthy children. …”
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  12. 1172
    por La Bonnardière, C., Laude, H., Berg, K.
    Publicado 1986
    “…Endogenous interferon (IFN) made by the newborn piglet in response to enteric coronavirus TGEV (transmissible gastroenteritis virus) infection was identified as leukocytic IFN (IFN-α). …”
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  13. 1173
    por Martin-Hijano, Laura, Sainz, Bruno
    Publicado 2020
    “…Interferons (IFNs) form a family of cytokines with pleiotropic effects that modulate the immune response against multiple challenges like viral infections, autoimmune diseases, and cancer. …”
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  14. 1174
    “…Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. …”
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  15. 1175
    “…Upon detection of viral infections, cells activate the expression of type I interferons (IFNs) and pro-inflammatory cytokines to control viral dissemination. …”
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  16. 1176
    “…This enhancement is inversely correlated with the expression of interferons and interferon stimulated genes (ISGs), which suppress expression of transfected genes at the mRNA level. …”
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  17. 1177
  18. 1178
  19. 1179
    “…Background: Anaemia is a major public health concern especially in African children living in malaria-endemic regions. Interferon-gamma (IFN-γ) is elevated during malaria infection and is thought to influence erythropoiesis and iron status. …”
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  20. 1180
    “…Here we propose to use low doses of hydroxychloroquine (50–100 mg daily orally) and intranasal interferon alpha-2b (IFN α-2b) spray (0.5 × 10(6) IU twice daily) for the prophylaxis of COVID-19. …”
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