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  1. 101
    “…The interferon system provides a powerful and universal intracellular defense mechanism against viruses. …”
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    Interferon, Mx, and viral countermeasures
  2. 102
    por Saffern, Miriam
    Publicado 2020
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    ACE2 is not induced by interferon
  3. 103
    por Hendricks, Matthew R., Savan, Ram
    Publicado 2020
    “…Type I and III interferons (IFNs) drive effective antiviral functions but differentially affect tissue homeostasis. …”
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    Interferon-λ at the Center of the Storm
  4. 104
    “…As a key participant in inflammation, interferon-gamma (IFN-γ) can be detected in different parts of the eye and is responsible for the breakdown of the blood-retina barrier and activation of inflammatory cells and other cytokines, which accelerate neovascularization and neuroglial degeneration. …”
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    Role of interferons in diabetic retinopathy
  5. 105
    “…Interferons (IFNs) are cytokines involved in the immune response that act on innate and adaptive immunity. …”
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    Forms and Methods for Interferon’s Encapsulation
  6. 106
    por Kim, Boram, Choi, Jaebok
    Publicado 2022
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    Editorial: Interferons and GvHD
  7. 107
    por Arnaiz, Esther, Harris, Adrian L.
    Publicado 2022
    “…In addition, tumor cells require an active interferon (IFN) signalling pathway for the success of many anticancer therapies, such as radiotherapy or chemotherapy. …”
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    Role of Hypoxia in the Interferon Response
  8. 108
    por Park, Yuri, Han, Sang Jun
    Publicado 2022
    “…Therefore, high interferon levels play a crucial role in endometriosis progression. …”
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    Interferon Signaling in the Endometrium and in Endometriosis
  9. 109
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    INTERFERON AND CELL DIVISION : III. Effect of Interferon on the Division Cycle of L1210 Cells In Vitro
  10. 110
    Publicado 1995
    “…The interferon (IFN) gamma production of splenocytes from closely related C57BL/10ScSn (Sn) and C57BL/10ScCr (Cr) mice was compared. …”
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    Interferon beta, a cofactor in the interferon gamma production induced by gram-negative bacteria in mice
  11. 111
    “…We recently reported that testicular germ cell tumours (TGCT) express a functional form of the proinflammatory cytokine interferon-gamma (IFNγ). The present study asked whether TGCT-derived IFNγ influences survival or death of neoplastic germ cells. …”
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    Malignant germ cell tumours of the testis express interferon-γ, but are resistant to endogenous interferon-γ
  12. 112
    “…RESULTS: Colonization with S. pneumoniae altered the expression of hundreds of genes over the course of the study, demonstrating that carriage is a dynamic process characterized by increased expression of a set of early inflammatory responses, including induction of a Type I Interferon response, and the production of several antimicrobial factors. …”
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    Streptococcus pneumoniae nasopharyngeal colonization induces type I interferons and interferon-induced gene expression
  13. 113
    “…PURPOSE: To study the effect of oxidation on the structure of recombinant human interferon beta-1a (rhIFNβ-1a) and its immunogenicity in wild-type and immune-tolerant transgenic mice. …”
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    Oxidized and Aggregated Recombinant Human Interferon Beta is Immunogenic in Human Interferon Beta Transgenic Mice
  14. 114
    “…BACKGROUND: Though an important percentage of patients with chronic hepatitis C virus (HCV) undergoing interferon (IFN) therapy develop depressive symptoms, the role of the IFN system in the pathogenesis of depressive disorders is not well understood. …”
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    Selective Hyper-responsiveness of the Interferon System in Major Depressive Disorders and Depression Induced by Interferon Therapy
  15. 115
    “…INTRODUCTION: Type 1 interferon (IFN)-inducible genes and their inducible products are upregulated in dermatomyositis muscle. …”
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    Type 1 Interferons Inhibit Myotube Formation Independently of Upregulation of Interferon-Stimulated Gene 15
  16. 116
    “…We identify interleukin (IL)-22 produced by group 3 innate lymphoid cells (ILC3s) as an amplifier of interferon (IFN)-λ signaling, a synergism required to curtail replication of rotavirus, the leading cause of childhood gastroenteritis. …”
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    Interferon-λ and interleukin-22 cooperate for the induction of interferon-stimulated genes and control of rotavirus infection
  17. 117
    “…Interferon-α (IFN-α) and IFN-λ are structurally distinct cytokines that bind to different receptors, but induce expression of similar sets of genes through Janus kinase (JAK)-signal transducers and activators of transcription (STAT) pathways. …”
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    STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-α
  18. 118
    “…In this study, we observed that the IAV PA protein could inhibit the production of IFN-β and interferon-stimulated genes induced by Sendai virus through interferon regulatory factor 3 (IRF3), but not through nuclear factor-kappaB (NF-kappaB). …”
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    Influenza A Virus PA Antagonizes Interferon-β by Interacting with Interferon Regulatory Factor 3
  19. 119
    “…The number of amino acid substitutions in the interferon (IFN) sensitivity-determining region (ISDR) of hepatitis C virus (HCV) NS5A is a strong predictor for the outcome of IFN-based treatment. …”
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    Interferon sensitivity-determining region of hepatitis C virus influences virus production and interferon signaling
  20. 120
    “…Direct-acting antiviral agents (DAAs) for hepatitis C treatment tend to fare better in individuals who are also likely to respond well to interferon-alpha (IFN), a surprising correlation given that DAAs target specific viral proteins whereas IFN triggers a generic antiviral immune response. …”
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    Modelling how responsiveness to interferon improves interferon-free treatment of hepatitis C virus infection
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