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  1. 1201
    “…Interferon-β (IFN-β) is a pleiotropic cytokine used for therapy of multiple sclerosis, which is also effective in suppression of viral and bacterial infections and cancer. …”
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    Interferon Beta Activity Is Modulated via Binding of Specific S100 Proteins
  2. 1202
    por Lin, Fuyu, Shen, Kunling
    Publicado 2020
    “…Various antiviral drugs have recently been tested. Type I interferon (IFN) is a regulatory protein involved in the innate immune response, with broad‐spectrum antiviral activities and the ability to directly block viral replication and support the immune response to eliminate virus infection. …”
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    Type I interferon: From innate response to treatment for COVID‐19
  3. 1203
    “…Chicken MDA5 (chMDA5), the essential accepted pattern recognition receptors for detecting cytoplasmic viral RNA in chicken, initiates interferon β (IFN-β) generation. However, there is an incomplete elucidation of regulating chMDA5-mediated IFN-β production. …”
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    Chicken optineurin suppresses MDA5-mediated interferon β production
  4. 1204
    por Too, Lay Khoon, Mitchell, Andrew
    Publicado 2020
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    Brains, bacteria and behaviors: the role of interferon-gamma in the pathogenesis of pneumococcal meningitis
  5. 1205
    por Bryson, Bryan D.
    Publicado 2021
    “…In this mSphere of Influence article, he reflects on how “IRG1 and inducible nitric oxide synthase act redundantly with other interferon-gamma-induced factors to restrict intracellular replication of Legionella pneumophila” by Price and colleagues (J. …”
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    mSphere of Influence: the Complexity of Interferon Gamma-Mediated Pathogen Control
  6. 1206
    “…Pestiviruses can prevent interferon (IFN) production to avoid the host innate immune response, and the N(pro) viral protein can play a critical role. …”
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    Disruption of interferon-β production by the N(pro) of atypical porcine pestivirus
  7. 1207
    por Rabin, Ronald L., Walter, Mark R.
    Publicado 2021
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    Editorial: Structures, Signaling Mechanisms, and Functions of Types I and III Interferons
  8. 1208
    “…Interferon (IFN) plays a role in immune and inflammation responses. …”
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    Interferon characterization associates with asthma and is a potential biomarker of predictive diagnosis
  9. 1209
    “…Type I interferon (IFN-I) plays a critical role in the antiviral immune response. …”
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    Gastrodin Inhibits Virus Infection by Promoting the Production of Type I Interferon
  10. 1210
    “…One of the most powerful and multifaceted cytokines produced by immune cells are type I interferons (IFNs), the basal secretion of which contributes to the maintenance of immune homeostasis, while their activation-induced production is essential to effective immune responses. …”
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    Type I Interferon Production of Plasmacytoid Dendritic Cells under Control
  11. 1211
    “…BACKGROUND: The Type I interferon response is an important first-line defense against viruses. …”
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    Positive natural selection in primate genes of the type I interferon response
  12. 1212
    “…We aim to review the efficacy and safety of Interferon Beta (IFN-β) in patients who have a confirmed COVID-19 diagnosis. …”
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    Effects of Interferon Beta in COVID-19 adult patients: Systematic Review
  13. 1213
    “…Recently, cases have been described in otherwise healthy individuals with neutralizing antibodies to interferon-gamma (nIFNγ-autoAb), especially in patients of Southeast Asian descent. …”
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    Treatment Dilemmas in Disseminated Nontuberculous Mycobacterial Infections With Interferon-gamma Autoantibodies
  14. 1214
    “…We investigated the current role of interferon‐alpha (IFNα) in hairy cell leukaemia (HCL) in a retrospective analysis of patients with HCL. …”
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    The current role of interferon in hairy cell leukaemia: clinical and molecular aspects
  15. 1215
    “…Severe coronavirus disease 2019 (COVID-19) is characterized by overproduction of immune mediators, but the role of interferons (IFNs) of the type I (IFN-I) or type III (IFN-III) families remains debated. …”
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    The interferon landscape along the respiratory tract impacts the severity of COVID-19
  16. 1216
    por Murphy, Eain A.
    Publicado 2021
    “…Albanese, et al., mBio 12:e03440-20, 2021, https://doi.org/10.1128/mBio.03440-20) revisits the impact of virus-encoded noncoding RNAs on key components of the interferon pathway and sheds light on how the extensive biological functions of Epstein-Barr virus (EBV) microRNAs (miRNAs) are on targeting both the induction and signaling cascades of interferon.…”
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    Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
  17. 1217
    “…Moreover, the pathophysiological mechanisms are distinct between each myositis subsets. Recently, interferon (IFN) pathways have been identified as key players implicated in the pathophysiology of myositis. …”
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    The role of interferons type I, II and III in myositis: A review
  18. 1218
    Publicado 2021
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    Interferon-beta-1a/natalizumab: Lack of efficacy: case report
  19. 1219
    “…Down syndrome (DS) is a unique genetic disease caused by the presence of an extra copy of chromosome 21, which carries four of the six interferon receptor (IFN-R) genes on its long arm. Recent studies reporting higher levels of interferon-stimulated gene (ISG) expression in primary immune cells studied ex vivo have suggested that the additional copies of the IFN-R genes in DS result in mild interferonopathy. …”
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    Interferon-Driven Immune Dysregulation in Down Syndrome: A Review of the Evidence
  20. 1220
    “…We use a minimal computational model of Type I Interferon signaling, focusing on Interferon-α and Interferon-β. …”
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    Determinants of Ligand Specificity and Functional Plasticity in Type I Interferon Signaling
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