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  1. 1281
    “…INTRODUCTION: Plasmacytoid dendritic cells (pDCs) play not only a central role in the antiviral immune response in innate host defense, but also a pathogenic role in the development of the autoimmune process by their ability to produce robust amounts of type I interferons (IFNs), through sensing nucleic acids by toll-like receptor (TLR) 7 and 9. …”
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    Inhibitor of IκB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells
  2. 1282
    “…Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), which poses a serious threat to the global pig industry. Interferons (IFNs) and IFN-stimulated genes (ISGs) play a key role in host antiviral defense. …”
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    Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway
  3. 1283
    “…This study aimed to investigate the effects of treatment with INF-β 1-a (interferon beta-1a) and IFN-β 1-b (interferon beta-1b) on COVID-19 inpatients. …”
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    Comparing the outcomes of treatment with INF-β 1-a (interferon beta-1a) and IFN-β 1-b (interferon beta-1b) among COVID-19 inpatients
  4. 1284
    “…As a cytokine, gamma-interferon (IFN-γ) is considered a key player in the fine-tuned orchestration of immune responses. …”
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    The Unitary Micro-Immunotherapy Medicine Interferon-γ (4 CH) Displays Similar Immunostimulatory and Immunomodulatory Effects than Those of Biologically Active Human Interferon-γ on Various Cell Types
  5. 1285
    “…Inflammatory responses induced by chronic cerebral hypoperfusion (CCH) play a critical role in the progression of vascular dementia. Stimulator of interferon genes (STING) signaling function as a key mediator of inflammation and immunological responses in the central nervous system (CNS), and resveratrol (RES) exerts potent anti-inflammatory effects. …”
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    Resveratrol reduces inflammatory response and detrimental effects in chronic cerebral hypoperfusion by down-regulating stimulator of interferon genes/TANK-binding kinase 1/interferon regulatory factor 3 signaling
  6. 1286
    por Gil Rodríguez, Luis Demetrio
    Publicado 1992
    Tesis Libro
    Conceptos actuales de la hepatitis C y uso del interferon : revisión bibliográfica /
  7. 1287
    “…Type I (-α/β) and Type III (IFN-λ) interferons are family members of cytokines that play an important role in fighting viral replication during the early phases of infection. …”
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    Type I and III interferons are good markers to monitor COVID-19 pathophysiology
  8. 1288
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    Rescue Therapy after Failure of HCV Antiviral Treatment with Interferon-Free Regimens
  9. 1289
    “…We combine multimodal imaging (cm-nm scale) with single nuclei RNA-sequencing to study Langat virus in wildtype and interferon alpha/beta receptor knockout (Ifnar(–/–)) mice to visualize viral pathogenesis and define molecular mechanisms. …”
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    Type I interferon shapes brain distribution and tropism of tick-borne flavivirus
  10. 1290
    “…Stimulator of interferon genes (STING) is a key mediator of type-I interferon (IFN-I) signaling in response to a variety of stimuli, but the contribution of STING to homeostatic processes is not fully characterized. …”
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    STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice
  11. 1291
    por Xiao, Chu, Li, Chunxiang, He, Jie
    Publicado 2023
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    Novel contributor to chemotherapy resistance: an interferon-dependent subtype of cancer-associated fibroblast
  12. 1292
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    Tuberculin skin tests and interferon-γ release assays in the diagnosis of tuberculosis infection
  13. 1293
    “…The interferon‐induced transmembrane proteins (IFITM) are implicated in several biological processes, including antiviral defense, but their modes of action remain debated. …”
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    Interferon‐inducible phospholipids govern IFITM3‐dependent endosomal antiviral immunity
  14. 1294
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    Rescue use of Pegylated Interferon in Dialysis Patient who Failed to Respond Sofosbuvir
  15. 1295
    “…This results in the expression of cytokines, including interferons (IFNs) which partly limit primary infection. …”
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    Viral modulation of type II interferon increases T cell adhesion and virus spread
  16. 1296
    “…Type I interferons have long been appreciated as a cytokine family that regulates antiviral immunity. …”
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    Harnessing type I interferon-mediated immunity to target malignant brain tumors
  17. 1297
    “…RESULTS: We show that IFNβ treatment in people with MS modifies the methylation profile of interferon response genes in a strong, targeted, and reproducible manner. …”
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    Interferon beta treatment is a potent and targeted epigenetic modifier in multiple sclerosis
  18. 1298
    “…Compelling evidence has shown that interferon (IFN)-γ has dual effects in multiple sclerosis and in its animal model of experimental autoimmune encephalomyelitis (EAE), with results supporting both a pathogenic and beneficial function. …”
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    Interferon-gamma ameliorates experimental autoimmune encephalomyelitis by inducing homeostatic adaptation of microglia
  19. 1299
    por Samuel, Charles E.
    Publicado 2023
    “…This virus was identified as the pathogen responsible for the severe respiratory disease, coronavirus disease-19 (COVID-19), which as of May 2023, has killed an estimated 6.9 million people globally according to the World Health Organization. The interferon (IFN) response, a cornerstone of antiviral innate immunity, plays a key role in determining the outcome of infection by SARS-CoV-2. …”
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    Interferon at the crossroads of SARS-CoV-2 infection and COVID-19 disease
  20. 1300
    “…PURPOSE: To address the limited utility of the interferon (IFN)-γ release assay (IGRA) caused by its variability and inconsistency. …”
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    Enhancing the interferon-γ release assay through omission of nil and mitogen values
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