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  1. 1301
    “…Exposure of human cells to interferon‐γ (IFNγ) results in a mitotically heritable yet reversible state called long‐term transcriptional memory. …”
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    STAT1 is required to establish but not maintain interferon‐γ‐induced transcriptional memory
  2. 1302
    “…Here, we use Klebsiella pneumoniae as a model of bacterial pneumonia and demonstrate that MAIT cell activation is independent of MR1 and primarily driven by type I interferons (IFNs). During Klebsiella infection, type I IFNs stimulate activation of murine and human MAIT cells, induce a Th1/cytotoxic transcriptional program, and modulate MAIT cell location within the lungs. …”
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    Type I interferons drive MAIT cell functions against bacterial pneumonia
  3. 1303
    Publicado 2023
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    Erratum: Commentary: Topical interferon: A novel approach to uveitic macula edema
  4. 1304
    “…Here, we demonstrate that the stimulator of interferon genes (STING) strengthens the host IFN-independent anti-hantaviral immunity. …”
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    STING strengthens host anti-hantaviral immunity through an interferon-independent pathway
  5. 1305
    “…Bladder cancer is a prevalent malignancy with limited therapeutic options, particularly for patients who are unresponsive to Bacillus Calmette-Guérin (BCG). The approval of interferon-α (IFNα) gene therapy with nadofaragene firadenovec (Adstiladrin(®)), the first gene therapy for genitourinary malignancies, has provided a promising alternative. …”
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    Interferon gene therapy with nadofaragene firadenovec for bladder cancer: from bench to approval
  6. 1306
    “…PURPOSE: Anti-interferon gamma antibody (AIGA) is a rare cause of adult onset immunodeficiency, leading to severe disseminated opportunistic infections with varying outcomes. …”
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    Characteristics and Outcomes of Anti-interferon Gamma Antibody-Associated Adult Onset Immunodeficiency
  7. 1307
    “…Following virus infections, type I interferons are synthesized to induce the expression of antiviral molecules and interfere with virus replication. …”
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    Protective versus Pathogenic Type I Interferon Responses during Virus Infections
  8. 1308
    “…Type 1 interferon stimulation highly up-regulates all elements of a ubiquitin-like conjugation system that leads to ISGylation of target proteins. …”
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    ISGylation-independent protection of cell growth by USP18 following interferon stimulation
  9. 1309
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    Interferon-γ couples CD8(+) T cell avidity and differentiation during infection
  10. 1310
    “…Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the salvage NAD(+) synthesis, is an interferon-inducible protein that inhibits the replication of several RNA and DNA viruses with unknown mechanism. …”
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    The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection
  11. 1311
    “…PURPOSE: The aim of this study was to report a case of ocular Mpox that responded favorably to treatment with topical interferon and oral doxycycline. METHODS: This is a case report of a previously healthy 24-year-old woman who developed a pustular rash, headache, fever, arthralgia, sore throat, and asthenia 3 weeks before attending to our clinic. …”
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    Adjuvant Topical Interferon Alpha 2b for the Treatment of Monkeypox Ocular Manifestations
  12. 1312
    “…In experimental models in vitro and in vivo, virus-induced interferon responses can augment host susceptibility to secondary bacterial infection. …”
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    Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection
  13. 1313
    por Zoladek, Jim, Nisole, Sébastien
    Publicado 2023
    “…The body’s first line of defense against viral infections is provided by the interferon (IFN) response. This antiviral defense mechanism takes place in two waves, namely the induction of type I IFNs triggered by viral infection, followed by the IFN signaling pathway, which leads to the synthesis of interferon-stimulated genes (ISGs), whose products inhibit viral replication. …”
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    Mosquito-borne flaviviruses and type I interferon: catch me if you can!
  14. 1314
    “…BACKGROUND: Interferon (IFN)-α is considered a key modulator of immunopathological processes through a signature-specific activation of mononuclear phagocytes (MPs). …”
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    Delayed polarization of mononuclear phagocyte transcriptional program by type I interferon isoforms
  15. 1315
    “…BACKGROUND: The whole-blood interferon-gamma release assay (IGRA) is recommended in some settings as an alternative to the tuberculin skin test (TST). …”
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    Feasibility, acceptability, and cost of tuberculosis testing by whole-blood interferon-gamma assay
  16. 1316
    “…In the current study we examined the effects of interferon (IFN)-γ, tumour necrosis factor (TNF)α, interleukin (IL)-1β and IL-6 on neurons. …”
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    Interferon-γ increases neuronal death in response to amyloid-β(1-42)
  17. 1317
    “…RESULTS: We demonstrated that the frequency of CD16+ interferon-gamma (IFN-gamma)+ natural killer cells in negative individuals over the age of 70 years is significantly higher than in positive individuals after in vitro stimulation with S. mansoni antigen extracts. …”
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    Production of interferon-gamma by natural killer cells and aging in chronic human schistosomiasis.
  18. 1318
    “…We investigated the regulation of human PML expression by interferons (IFNs) and IL-1 in various human haematopoietic lines (U937, THP1, HL60, NB4), in human diploid fibroblasts and in human peripheral blood leukocytes. …”
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    Induction of the pro-myelocytic leukaemia gene by type I and type II interferons.
  19. 1319
    “…Objective: The mechanism whereby the placental cells of a human immunodeficiency virus (HIV)-1-infected mother protect the fetus from HIV-1 infection is unclear. Interferons (IFNs) inhibit the replication of viruses by acting at various stages of the life cycle and may play a role in protecting against vertical transmission of HIV-1. …”
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    Production of Interferons and β-Chemokines by Placental Trophoblasts of HIV-1-Infected Women
  20. 1320
    “…CONCLUSIONS: Defects in interferon signaling represent novel, dominant mechanisms of immune dysfunction in cancer. …”
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    Down-Regulation of the Interferon Signaling Pathway in T Lymphocytes from Patients with Metastatic Melanoma
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