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  1. 1361
    “…Neutralizing autoantibodies to type I, but not type II, interferons (IFNs) are found at high titers in almost every patient with autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED), a disease caused by AIRE gene mutations that lead to defects in thymic T-cell selection. …”
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    Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes
  2. 1362
    “…Irga6, a myristoylated, interferon-inducible member of the immunity-related GTPase family, contributes to disease resistance against Toxoplasma gondii in mice. …”
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    Inactive and Active States of the Interferon-inducible Resistance GTPase, Irga6, in Vivo
  3. 1363
    “…BACKGROUND: Type-I interferons, type-II interferons, and the IL-10 family are helical cytokines with similar three-dimensional folds. …”
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    The Role of Genomic Data in the Discovery, Annotation and Evolutionary Interpretation of the Interferon-Lambda Family
  4. 1364
    “…BACKGROUND: In recent years, the impact of antituberculous treatment on interferon (IFN)-γ response to Mycobacterium tuberculosis antigens has been widely investigated, but the results have been controversial. …”
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    In Vivo and In Vitro Effects of Antituberculosis Treatment on Mycobacterial Interferon-γ T Cell Response
  5. 1365
    “…BACKGROUND: Interferon regulatory factor (IRF) family members have been implicated as critical transcription factors that function in immune response, hematopoietic differentiation and cell growth regulation. …”
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    Functional Analysis of a Dominant Negative Mutation of Interferon Regulatory Factor 5
  6. 1366
    “…The regulation mechanism of interferon (IFN) and IFN-stimulated genes is a very complex procedure and is dependent on cell types and virus species. …”
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    Interferon-Stimulated Genes Response in Endothelial Cells Following Hantaan Virus Infection
  7. 1367
    “…Interferons (IFNs) direct innate and acquired immune responses and, accordingly, are used therapeutically to treat a number of diseases, yet the diverse effects they elicit are not fully understood. …”
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    Promyelocytic Leukemia Zinc Finger Protein Regulates Interferon-Mediated Innate Immunity
  8. 1368
    “…Chlamydiae are obligate intracellular pathogens that are sensitive to pro-inflammatory cytokine interferon-γ. IFN-γ-inducible murine p47 GTPases have been demonstrated to function in resistance to chlamydia infection in vivo and in vitro. …”
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    Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γ
  9. 1369
    “…The outcome data from prospective clinical trials that studied interferon and ribavirin therapy was then mapped onto this new tree. …”
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    The Evolution of the Major Hepatitis C Genotypes Correlates with Clinical Response to Interferon Therapy
  10. 1370
    “…Since the 1990s the results of several clinical trials with immunomodulatory agents have changed the therapeutic approach to this disease. Interferon beta (IFNβ)-1b represents the pioneer of those therapies. …”
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    Review of interferon beta-1b in the treatment of early and relapsing multiple sclerosis
  11. 1371
    “…We report that type I interferons (IFNs) are essential mediators of the lethal response to TNF. …”
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    Type I interferon drives tumor necrosis factor–induced lethal shock
  12. 1372
    por Boo, Kyung-Hyun, Yang, Joo-Sung
    Publicado 2010
    “…Through activation of transcription factors, such as interferon regulatory factor-3, 5, and 7 (IRF-3, 5, 7) or nuclear factor-κB (NF-κB), type I interferons are induced, and antiviral proteins such as myxovirus-resistance protein (Mx) GTPase, RNA-dependent Protein Kinase (PKR), ribonuclease L (RNase L), Oligo-adenylate Synthetase (OAS) and Interferon Stimulated Gene (ISG) are further expressed. …”
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    Intrinsic Cellular Defenses against Virus Infection by Antiviral Type I Interferon
  13. 1373
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    Interferons and IRF/Stat transcription factors in the regulation of immunity, oncogenesis and bone remodeling
  14. 1374
    por Rose, Kristine M., Weiss, Susan R.
    Publicado 2009
    “…While there are many studies of the adaptive immune response to MHV, there has until recently been scant information on the type I interferon (IFN) response to MHV. The relationship between MHV and the IFN-α/β response is paradoxical. …”
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    Murine Coronavirus Cell Type Dependent Interaction with the Type I Interferon Response
  15. 1375
    “…We investigated the role of negative regulators of interferon signaling known as suppressors of cytokine signaling (SOCS) in mediating interferon-resistance in human melanoma cells. …”
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    Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells
  16. 1376
    “…The interferons are a complex group of virally induced proteins produced by activated macrophages and lymphocytes, which have become the mainstay of therapy for hepatitis C infection. …”
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    Irreversible Pulmonary Hypertension Associated with the use of Interferon Alpha for Chronic Hepatitis C
  17. 1377
    por Choi, Young, Nicholas, John
    Publicado 2010
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    Bim nuclear translocation and inactivation by HHV-8 interferon regulatory factor 1
  18. 1378
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    Changes in Glucose and Glutamine Lymphocyte Metabolisms Induced by Type I Interferon α
  19. 1379
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    Effect of LPS, dsRNA or interferons on the phagocytosis of dying cells or mycobacteria by macrophages
  20. 1380
    por Nakanishi, Koji, Saitoh, Satoshi
    Publicado 2011
    “…OBJECTIVE: This study clarified characteristics of interferon-associated type 1 diabetes. RESEARCH DESIGN AND METHODS: The study compared 12 patients with interferon-associated type 1 diabetes with 128 patients with type 1A diabetes with respect to clinical characteristics, and with 10 patients without diabetes despite interferon therapy and 136 normal controls with respect to HLA allele distributions. …”
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    Clinical and Genetic Characteristics of Patients With Type 1 Diabetes Associated With Interferon Therapy
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