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  1. 121
    “…The induction of interferon by avian infectious bronchitis virus (IBV) and the sensitivity of IBV to interferon were studied. …”
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    Studies on avian infectious bronchitis virus (IBV): III. Interferon induction by and sensitivity to interferon of IBV
  2. 122
    “…The response was accompanied by a variable induction of predominantly interferon-beta and/or -lambda, but blocking these interferons did not affect ISG expression induction. …”
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    Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation
  3. 123
    Publicado 1988
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    Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta
  4. 124
    “…The innate immune system is the first line of the host’s defense, and studying the mechanisms of the negative regulation of interferon (IFN) signaling is important for maintaining the balance of innate immune responses. …”
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    NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3
  5. 125
    Publicado 1995
    “…A very different outcome was observed with inbred 129Sv mice whose receptors for interferon alpha/beta or interferon gamma had been inactivated by homologous recombination. …”
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    Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors
  6. 126
    “…INTRODUCTION: Interleukin (IL)-17 is a pro-inflammatory cytokine in rheumatoid arthritis (RA) and collagen-induced arthritis (CIA). Since interferon (IFN)-γ inhibits Th17 cell development, IFN-γ receptor knockout (IFN-γR KO) mice develop CIA more readily. …”
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    Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-γ and counteraction by interferon-γ
  7. 127
    “…Interferons (IFNs) are secreted proteins of the cytokine family that regulate innate and adaptive immune responses to infection. …”
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    The bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferons
  8. 128
    “…Although Daxx is encoded by a type I (α/β) interferon-stimulated gene, the requirement for Daxx in the interferon anti-retroviral response has not been elucidated. …”
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    The interferon-inducible antiviral protein Daxx is not essential for interferon-mediated protection against avian sarcoma virus
  9. 129
    “…There is a debate on whether invertebrates possess an antiviral immunity similar to the interferon (IFN) system of vertebrates. The Vago gene from arthropods encodes a viral-activated secreted peptide that restricts virus infection through activating the JAK-STAT pathway and is considered to be a cytokine functionally similar to IFN. …”
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    Activation of Vago by interferon regulatory factor (IRF) suggests an interferon system-like antiviral mechanism in shrimp
  10. 130
    “…Regimens were grouped into: interferon- and ribavirin (RBV)-containing (±sofosbuvir [SOF]), interferon-free RBV-containing (RBV + SOF ± ledipasvir [LDV]), and interferon-free RBV-free (LDV/SOF). …”
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    Adherence to treatment of chronic hepatitis C: from interferon containing regimens to interferon and ribavirin free regimens
  11. 131
    “…We used CpG (TLR9 ligand), R848 (TLR7 ligand), or recombinant IFN-α to induce interferon-stimulated genes (ISGs) and proteins, and observed that this response was markedly diminished by BKs, klk1 (tissue kallikrein), or captopril (an ACE inhibitor). …”
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    Kallikrein–Kinin System Suppresses Type I Interferon Responses: A Novel Pathway of Interferon Regulation
  12. 132
    “…Following infections, interferons (IFNs) are produced as the first and the main anti-viral cytokines to combat the virus. …”
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    Basal interferon signaling and therapeutic use of interferons in controlling rotavirus infection in human intestinal cells and organoids
  13. 133
    “…In this study, we tried to control the amount of murine interferon-γ (IFN-γ) secreted from transplanted murine mesenchymal stem cell line C3H10T1/2 cells to achieve safe cell-based IFN-γ gene therapy for cancer. …”
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    Cell-based interferon gene therapy using proliferation-controllable, interferon-releasing mesenchymal stem cells
  14. 134
    “…ABSTRACT: Genetic variation and genotype of Hepatitis B virus (HBV) are related to the efficiency of interferon alpha (IFN-α)-based antiviral therapy. However, the correlation of variation in interferon-stimulated response element (ISRE) and HBV genotype response to IFN-α therapy remains elusive. …”
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    The response of hepatitis B virus genotype to interferon is associated with a mutation in the interferon-stimulated response element
  15. 135
    por Bass, DM
    Publicado 1997
    “…RESULTS: Interleukin (IL)-1, interferon (IFN)-alpha, and IFN-gamma pretreatment led to a dose-dependent resistance to rotavirus infection. …”
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    Interferon gamma and interleukin 1, but not interferon alfa, inhibit rotavirus entry into human intestinal cell lines
  16. 136
    “…Rabies, caused by rabies virus (RABV), is a fatal neurological disease that still causes more than 59,000 human deaths each year. Type III interferon IFN-λs are cytokines with type I IFN-like antiviral activities. …”
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    Interferon-λ Attenuates Rabies Virus Infection by Inducing Interferon-Stimulated Genes and Alleviating Neurological Inflammation
  17. 137
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    Interferon-γ and voriconazole combined therapy for refractory meningeal coccidioidomycosis in a patient with interferon-γ deficiency
  18. 138
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    Interferon α kinoid induces neutralizing anti-interferon α antibodies that decrease the expression of interferon-induced and B cell activation associated transcripts: analysis of extended follow-up data from the interferon α kinoid phase I/II study
  19. 139
    “…Interferons (IFNs) are antiviral cytokines that play a key role in the innate immune response to viral infections. …”
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    Viral recognition and the antiviral interferon response
  20. 140
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    Interferon-β for treatment of rheumatoid arthritis?
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