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  1. 1461
    “…In addition, DNA fragmentation detected upon Candid#1 infection of type I interferon (IFN)-deficient Vero cells suggested a type I IFN-independent mechanism of apoptosis induction in response to JUNV. …”
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  2. 1462
  3. 1463
    por Wang, Rong, Zhang, Yan-Jin
    Publicado 2014
    “…Interferons (IFNs) are important components in innate immunity involved in the first line of defense to protect host against viral infection. …”
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  4. 1464
  5. 1465
  6. 1466
    “…InterFeron Inducible TransMembrane proteins 1–3 (IFITM1, IFITM2 and IFITM3) are a family of proteins capable of inhibiting the cellular entry of numerous human and animal viruses. …”
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  7. 1467
    “…Infection with the hepatitis C virus (HCV) is a major cause of chronic liver diseases and hepatocellular carcinoma worldwide, and thus represents a significant public health problem. The type I interferon (IFN), IFNα, has been successful in treating HCV-infected patients, but current IFN-based treatment regimens for HCV have suboptimal efficacy, and relatively little is known about why IFN therapy eliminates the virus in some patients but not in others. …”
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  8. 1468
    “…We found that mice genetically deficient in the transcription factor, interferon (IFN) regulatory factor-7 (IRF7), made significantly higher CXCL13 protein levels in the CNS compared with wild-type (WT) controls. …”
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  9. 1469
    “…The development of biopharmaceutical agents, including the interferons (IFN), offers new treatment options for a wide range of medical conditions. …”
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  10. 1470
  11. 1471
  12. 1472
    “…Interferon regulatory factor 9 (IRF9) has various biological functions and regulates cell survival; however, its role in vascular biology has not been explored. …”
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  13. 1473
    “…The transcription factor interferon regulatory factor 3 (IRF3) is activated by pathogen recognition receptors and induces interferon-β production. …”
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  14. 1474
  15. 1475
  16. 1476
    “…The knowledge of correct using interferon-beta (IFN-β) and attitude toward medical care were assessed using self-reported questionnaires consisted of 25 items with validity of multidisciplinary panel and pre-testing on 20 patients. …”
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  17. 1477
    “…BACKGROUND: Type I interferons (IFNs), including IFN-alpha (IFNA) and IFN-beta (IFNB), have anti-inflammatory properties and are used to treat patients with autoimmune and inflammatory disorders. …”
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  18. 1478
  19. 1479
    “…BACKGROUND: It has been reported that interferon-γ (IFN-γ)–induced inflammatory markers, such as circulating neopterin and kynurenine-to-tryptophan ratio (KTR), are increased in patients with cancer and are also a predictor of poor prognosis. …”
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  20. 1480
    “…OBJECTIVE: The effect of interleukin (IL)-29, a new therapeutic agent similar to type I interferons (IFNs), on IFN-α secretion of human plasmacytoid dendritic cells (pDCs) has not been studied. …”
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