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1541“…BACKGROUND: This research aimed to explore the effects of interferon-γ (IFN-γ) polymorphisms and expression profile on susceptibility to ankylosing spondylitis (AS) in a Chinese population. …”
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1542por Mbofung, Rina M., McKenzie, Jodi A., Malu, Shruti, Zhang, Min, Peng, Weiyi, Liu, Chengwen, Kuiatse, Isere, Tieu, Trang, Williams, Leila, Devi, Seram, Ashkin, Emily, Xu, Chunyu, Huang, Lu, Zhang, Minying, Talukder, Amjad H., Tripathi, Satyendra C., Khong, Hiep, Satani, Nikunj, Muller, Florian L., Roszik, Jason, Heffernan, Timothy, Allison, James P., Lizee, Gregory, Hanash, Sam M., Proia, David, Amaria, Rodabe, Davis, R. Eric, Hwu, Patrick“…Mechanistic studies reveal that HSP90 inhibition results in upregulation of interferon response genes, which are essential for the enhanced killing of ganetespib treated melanoma cells by T cells. …”
Publicado 2017
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1543por Pallocca, Giorgia, Nyffeler, Johanna, Dolde, Xenia, Grinberg, Marianna, Gstraunthaler, Gerhard, Waldmann, Tanja, Rahnenführer, Jörg, Sachinidis, Agapios, Leist, Marcel“…As a case study to this issue, we characterized human interferon-beta (IFNβ) as potential developmental toxicant affecting neural crest cells (NCC). …”
Publicado 2017
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1544por Lucas-Hourani, Marianne, Dauzonne, Daniel, Munier-Lehmann, Hélène, Khiar, Samira, Nisole, Sébastien, Dairou, Julien, Helynck, Olivier, Afonso, Philippe V., Tangy, Frédéric, Vidalain, Pierre-Olivier“…Most importantly, we establish that pyrimidine deprivation can amplify the production of both type I and type III interferons by cells stimulated with retinoic acid-inducible gene 1 (RIG-I) ligands. …”
Publicado 2017
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1545“…BACKGROUND: The QuantiFERON Gold-in-tube (QFT) test is an Interferon Gamma Release Assay (IGRA) used to indirectly diagnose tuberculosis infection (TBI). …”
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1546“…OBJECTIVE: Interferon-α (IFN) therapy can cause depressive symptom which may lead to drug discontinuation. …”
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1547por Cuellar, Trinna L., Herzner, Anna-Maria, Zhang, Xiaotian, Goyal, Yogesh, Watanabe, Colin, Friedman, Brad A., Janakiraman, Vasantharajan, Durinck, Steffen, Stinson, Jeremy, Arnott, David, Cheung, Tommy K., Chaudhuri, Subhra, Modrusan, Zora, Doerr, Jonas Martin, Classon, Marie, Haley, Benjamin“…This is coincident with induction of a type I interferon response and apoptosis through the dsRNA-sensing pathway. …”
Publicado 2017
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1548“…For most viruses, this includes subverting the expression of interferon (IFN), a signaling molecule that can stimulate production of a vast array of antiviral gene products. …”
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1549“…Type III interferons (IFNs) (or IFN-λ) are the latest addition to the IFN family. …”
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1550por Lasseaux, Corentin, Fourmaux, Marie-Pierre, Chamaillard, Mathias, Poulin, Lionel Franz“…Herein, we show that type I interferons signaling promotes the differentiation of monocyte-derived phagocytes at the level of their progenitors during a mouse model of endotoxemia. …”
Publicado 2017
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1551
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1552por Prow, Natalie A., Tang, Bing, Gardner, Joy, Le, Thuy T., Taylor, Adam, Poo, Yee S., Nakayama, Eri, Hirata, Thiago D. C., Nakaya, Helder I., Slonchak, Andrii, Mukhopadhyay, Pamela, Mahalingam, Suresh, Schroder, Wayne A., Klimstra, William, Suhrbier, Andreas“…The effect was not associated with a detectable fever, but was dependent on type I interferon responses. Bioinformatics analyses of RNA-Seq data after injection of poly(I:C)/jetPEI suggested the unfolded protein response and certain type I interferon responses are promoted when feet are slightly warmer. …”
Publicado 2017
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1553por Lemos, Livia Lovato Pires de, Guerra Júnior, Augusto Afonso, Santos, Marisa, Magliano, Carlos, Diniz, Isabela, Souza, Kathiaja, Pereira, Ramon Gonçalves, Alvares, Juliana, Godman, Brian, Bennie, Marion, Zimmermann, Ivan Ricardo, dos Santos, Vânia Crisitna Canuto, Pretramale, Clarice Alegre, Acurcio, Francisco de Assis“…A recent Cochrane systematic review demonstrated that intramuscular interferon beta 1a (IFN-β-1a-IM) was inferior to the other beta interferons (IFN-βs) for multiple sclerosis (MS). …”
Publicado 2017
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1554“…BACKGROUND: To evaluate therapeutic outcomes of interferon alpha-2a (IFNα2a) treatment in patients with Behcet’s disease who were refractory to immunosuppressive agents. …”
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1555“…In the largest discordant subset (n = 63 genes) we identified an impaired type I interferon and STAT1 response in multiple AETRIs during the acute phase of the exacerbation and an upregulated STAT1 response at baseline. …”
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1556por Aarreberg, Lauren D., Wilkins, Courtney, Ramos, Hilario J., Green, Richard, Davis, Michael A., Chow, Kwan, Gale, Michael“…Induction of interferon beta (IFN-β), IFN-stimulated genes (ISGs), and inflammatory responses is critical for control of viral infection. …”
Publicado 2018
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1557por Kim, Dae Seong, Jang, In Keun, Lee, Myoung Woo, Ko, Young Jong, Lee, Doo-Hoon, Lee, Ji Won, Sung, Ki Woong, Koo, Hong Hoe, Yoo, Keon Hee“…In this study, we aimed to identify the effect of interferon (IFN)-γ priming on immunomodulation by MSCs and elucidate the possible mechanism underlying their properties for the clinical treatment of allogeneic conflicts. …”
Publicado 2018
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1558por Kimura, Akihiko, Ishida, Yuko, Furuta, Machi, Nosaka, Mizuho, Kuninaka, Yumi, Taruya, Akira, Mukaida, Naofumi, Kondo, Toshikazu“…BACKGROUND: A clear understanding of the molecular mechanisms underlying hemodynamic stress‐initiated cardiac hypertrophy is important for preventing heart failure. Interferon‐γ (IFN‐γ) has been suggested to play crucial roles in various diseases other than immunological disorders by modulating the expression of myriad genes. …”
Publicado 2018
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1559por Teramura, Yasufumi, Watanabe, Yoshihiko, Kan, Norimichi, Masuda, Tohru, Kuribayashi, Kagemasa“…We investigated the mechanism of host immune responses against two interferon‐γ (IFN‐γ) gene‐transduced tumors, plasmacytoma MOPC104E(Muγ) and mammary cancer SC115(Kγ), which originally had weak immunogenicity. …”
Publicado 1993
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1560por Norioka, Ken‐ichi, Mitaka, Toshihiro, Mochizuki, Yohichi, Hara, Masako, Kawagoe, Mitsuhiro, Nakamura, Haruo“…The interaction of interleukin‐1 (IL‐1) and interferon‐γ (IFN‐γ) actions on several aspects of angiogenesis in vitro and in vivo was studied. …”
Publicado 1994
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