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  1. 141
    “…Fifteen patients with locally advanced refractory breast cancer have been treated with recombinant leucocyte interferon ( rIFN -alpha A) for up to 12 weeks. Toxicity was considerable with the initial dosage schedule employed but became acceptable after reducing the starting dose by 50%. …”
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    Recombinant interferon in advanced breast cancer.
  2. 142
    “…A Phase 2 trial was conducted using intramuscular lymphoblastoid interferon (IFN, Wellcome Research Laboratories), 4 MU per day, in 10 patients with chemotherapy-resistant teratomas. …”
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    Response of differentiated but not anaplastic teratoma to interferon.
  3. 143
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    Central nervous system toxicity of interferon.
  4. 144
    Publicado 1982
    “…Analysis of human beta interferon (IFN) mRNA preparations obtained from poly(I) . poly (C)-induced human diploid fibroblasts (FS-4) and from several similarly induced human-mouse somatic cell hybrids by electrophoresis through agarose-CH3HgOH tube gels led to the detection of at least five translationally active human IFN-beta mRNA species. …”
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    Multiple human beta interferon genes
  5. 145
    Materias: “…Interferon Induction ⋅ II…”
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    Double-Stranded Polynucleotides as Interferon Inducers
  6. 146
    por Burke, D. C.
    Publicado 1970
    Materias: “…Interferon Induction ⋅ I…”
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    Molecular Aspects of Interferon Induction by Viruses
  7. 147
    “…The development of resistance in response to interferon depends on cellular RNA synthesis and probably also on cellular protein synthesis. …”
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    Development of the Antiviral State in Response to Interferon
  8. 148
    por Middleton, M R, Thatcher, N
    Publicado 2001
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    Adjuvant interferon in melanoma – a resurrection?
  9. 149
    por Middleton, M R
    Publicado 2000
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    Adjuvant interferon in the treatment of melanoma – reply
  10. 150
    por Murren, J. R., Buzaid, A. C.
    Publicado 1989
    “…Interferons (IFNs) are proteins with a wide range of biological effects. …”
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    The role of interferons in the treatment of malignant neoplasms.
  11. 151
    “…INTERFEROME is an open access database of types I, II and III Interferon regulated genes (http://www.interferome.org) collected from analysing expression data sets of cells treated with IFNs. …”
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    INTERFEROME: the database of interferon regulated genes
  12. 152
    “…Since their discovery in the 1950s interferons have been the scope of investigation in many diseases as therapeutic as well as pathogenetic factors. …”
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    Interferons and their potential in the treatment of ocular inflammation
  13. 153
    por Theofilopoulos, A
    Publicado 2003
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    Cyclin kinase inhibitors and interferons in lupus
  14. 154
    “…The pleiotropic cytokine interferon alpha is involved in multiple aspects of lupus etiology and pathogenesis. …”
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    Interferon Alpha in Systemic Lupus Erythematosus
  15. 155
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    The Role of Interferon in Hepatitis B Therapy
  16. 156
    por Trinchieri, Giorgio
    Publicado 2010
    “…Although the role of type I interferon (IFN) in the protection against viral infections has been known and studied for decades, its role in other immunologically relevant scenarios, including bacterial infections, shock, autoimmunity, and cancer, is less well defined and potentially much more complicated.…”
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    Type I interferon: friend or foe?
  17. 157
    “…Embolization of feeding artery was attempted but not feasible. We used Interferon –alpha– 2b (IFN α 2b), in a dosage of 3million IU/m(2) /day subcutaneously. …”
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    KASABACH MERRITT SYNDROME: MANAGEMENT WITH INTERFERON
  18. 158
    “…Type I interferons are pleiotropic cytokines with antiviral, antitumor and immunoregulatory functions. …”
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    Overview of the biology of type I interferons
  19. 159
    “…Recently, several large genome-wide association studies have identified single nucleotide polymorphisms (SNPs) linked to interferon lambda 3 (IFNλ3) that are associated with the spontaneous resolution and successful treatment of HCV infection. …”
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    Interferon lambdas: the next cytokine storm
  20. 160
    “…Type-I interferons (IFN-I) play an important role in the innate immune response to several retroviruses. …”
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    Effect of Type-I Interferon on Retroviruses
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