“…Antiviral activities of a recombinant feline interferon (rFeIFN) KT-80 were evaluated against feline enteropathogenic viruses in feline and canine cell lines. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Several lines of evidence have supported the role of immunological mechanisms in the pathogenesis of multiple sclerosis (MS) and new immunomodulatory strategies for its treatment, e.g. subcutaneous application of interferon (IFN)-β, have emerged. We investigated the ability of peripheral blood mononuclear cells (PBMC) in 21 consecutive patients with clinically definite MS to produce interferons and lymphokines in response to viral or mitogenic stimulation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The protein applied in this work is human recombinant interferon-α2a (hrIFN-α2a), which is a commercial drug applied for the treatment of virus-infected diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Materias: “…PP2-200 Interferon response in murine plasmacytoid dendritic cells after SARS coronavirus infection…”
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…BACKGROUND: Juvenile dermatomyositis (JDM) is a systemic autoimmune disease with a prominent interferon (IFN) signature, but the pathogenesis of JDM and the etiology of its IFN signature remain unknown. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Type I interferons (IFNs) are soluble molecules that exert potent antiviral activity and are currently used for the treatment of a panel of viral infections. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…While the safety and efficacy profiles of orally administered bovine interferon (IFN) alpha have been documented, the mechanism(s) that result in clinical benefits remain elusive. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Herein, we report the sensitivity of SARS-CoV-2 to recombinant human interferons α and β (IFNα/β). Treatment with IFN-α or IFN-β at a concentration of 50 international units (IU) per milliliter reduces viral titers by 3.4 log or over 4 log, respectively, in Vero cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Myeloproliferative neoplasms (MPN) are associated with an increased risk of arterial and venous thrombosis. Pegylated-interferon alpha (IFN) and hydroxyurea (HU) are commonly used to treat MPN, but their effect on hemostasis has not yet been studied. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Type I interferons (IFN-I) are a group of related proteins that help regulate the activity of the immune system and play a key role in host defense against viral infections. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…By combining DNA microarray and genomic data analyses to predict DNA binding motifs, we identified the transcription factor Interferon Regulatory Factor 7 (IRF7) as a possible regulator of genes related to adipocyte hypertrophy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Interferon-stimulated genes (ISGs) play an important role in antiviral innate immune responses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We report a case of disseminated Mycobacterium szulgai infection of cervical lymphadenitis and pulmonary involvement with positive anti-interferon-gamma autoantibodies. The patient was successfully treated with rifampin, ethambutol, and clarithromycin. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we assessed how type III interferons (IFN-λ) contribute to the pathogenesis induced by RNA viruses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mechanistically, type I interferon (IFN) expressed following infection promotes apoptosis, activation, and inhibitory receptor expression, and interferon-insensitive CAR T cells enable combinatorial therapy with VSVmIFNβ. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We then experimentally demonstrated that, when present, the interference is not related to a block of viral entry but rather to type I and type III interferon (IFN), the front-line antiviral defense of the respiratory mucosa. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Porcine deltacoronavirus (PDCoV) is a novel swine enteropathogenic coronavirus that causes watery diarrhea, vomiting and mortality in nursing piglets. Type III interferons (IFN-λs) are the major antiviral cytokines in intestinal epithelial cells, the target cells in vivo for PDCoV. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso