Materias dentro de su búsqueda.
Materias dentro de su búsqueda.
-
1741“…The effect of the screened drug on DN was analyzed through in vitro and in vivo model experiments. Interferon regulatory factor 4 (IRF4) in DN was identified to be upregulated compared with that in normal control tissues. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1742por Chen, Chia-Ling, Tseng, Po-Chun, Satria, Rahmat Dani, Nguyen, Thi Thuy, Tsai, Cheng-Chieh, Lin, Chiou-Feng“…Furthermore, while the signaling transduction of GSK-3 facilitates proinflammatory interferon (IFN)-γ in vitro and in vivo, the blockade of GSK-3 can be protective, as shown by an IFN-γ-induced immune hepatitis model. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1743por Patil, Prabhumallikarjun, Gray, Rachel, Goldman-Yassen, Adam, Aguilera, Dolly, Castellino, Robert, Janss, Anna, Mazewski, Claire“…Successful treatment with interferon alfa(INFα) after progression is reported in the literature. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1744por Taura, Manabu, Frank, John A., Takahashi, Takehiro, Kong, Yong, Kudo, Eriko, Song, Eric, Tokuyama, Maria, Iwasaki, Akiko“…Because TTTC doublets are present in interferon (IFN)-stimulated response elements (ISRE), we hypothesized that A3A may impact IFN-stimulated gene (ISG) expression. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1745“…Anifrolumab, an anti‐interferon‐α receptor monoclonal antibody, in moderate‐to‐severe systemic lupus erythematosus. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1746por Znaidia, Mariem, Demeret, Caroline, van der Werf, Sylvie, Komarova, Anastassia V.“…SARS-CoV-2 is characterized by an important capacity to circumvent the innate immune response. The early interferon (IFN) response is necessary to establish a robust antiviral state. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1747“…The interferon-induced transmembrane protein 3 (IFITM3), a small molecule transmembrane protein induced by interferon, is generally conserved in vertebrates, which can inhibit infection by a diverse range of pathogenic viruses such as influenza virus. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1748por Yin, Mengge, Wen, Wei, Wang, Haoyuan, Zhao, Qiongqiong, Zhu, Hechao, Chen, Huanchun, Li, Xiangmin, Qian, Ping“…Collectively, our results revealed that PSV inhibits the production of type I interferon to escape host antiviral immunity through cleaving and degrading the adaptor molecules.…”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1749por Xu, Tiantian, Peng, Bo, Liu, Mengmeng, Liu, Qingjing, Yang, Junya, Qu, Minli, Liu, Na, Lin, Lizhen, Wu, Jing“…The genes we tested were IL6 (interleukin 6), IL6R (interleukin 6 receptor), FOXP3 (forkhead box P3), TLR2 (toll-like receptor 2), TLR4 (toll-like receptor 4), IFNL3 (interferon lambda 3, formerly known as IL28B), and IFNL4 (interferon lambda 4, formerly known as IL29). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1750por Eto, Shohei, Nukui, Yoko, Tsumura, Miyuki, Nakagama, Yu, Kashimada, Kenichi, Mizoguchi, Yoko, Utsumi, Takanori, Taniguchi, Maki, Sakura, Fumiaki, Noma, Kosuke, Yoshida, Yusuke, Ohshimo, Shinichiro, Nagashima, Shintaro, Okamoto, Keisuke, Endo, Akifumi, Imai, Kohsuke, Kanegane, Hirokazu, Ohnishi, Hidenori, Hirata, Shintaro, Sugiyama, Eiji, Shime, Nobuaki, Ito, Masanori, Ohge, Hiroki, Kido, Yasutoshi, Bastard, Paul, Casanova, Jean-Laurent, Ohara, Osamu, Tanaka, Junko, Morio, Tomohiro, Okada, Satoshi“…PURPOSE: Autoantibodies (aAbs) to type I interferons (IFNs) have been found in less than 1% of individuals under the age of 60 in the general population, with the prevalence increasing among those over 65. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1751por Sur, Debpali, Leonova, Katerina, Levi, Bar, Markowitz, Shany Ivon, Cohen-Harazi, Raichel, Gitlin, Ilya, Gurova, Katerina, Gudkov, Andrei, Pinhasov, Albert, Koman, Igor, Nesher, Elimelech“…Interferon (IFN) signaling resulting from external or internal inflammatory processes initiates the rapid release of cytokines and chemokines to target viral or bacterial invasion, as well as cancer and other diseases. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1752
-
1753por Zhou, Zijun, Hollink, Iris H. I. M., Bouman, Arjan, Lourens, Mirthe S., Brooimans, Rik A., van Ham, Tjakko J., Fraaij, Pieter L. A., van Rossum, Annemarie M. C., Zijtregtop, Eline A. M., Dik, Willem A., Dalm, Virgil A. S. H., van Hagen, P. Martin, Ijspeert, Hanna, Vermont, Clementien L.Enlace del recurso
Publicado 2022
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1754“…However, the virus has developed many strategies to delay interferon secretion and disarm cellular defense by intervening in interferon-associated signaling pathways on multiple levels. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1755por Jiao, Huipeng, Wachsmuth, Laurens, Wolf, Simone, Lohmann, Juliane, Nagata, Masahiro, Kaya, Göksu Gökberk, Oikonomou, Nikos, Kondylis, Vangelis, Rogg, Manuel, Diebold, Martin, Tröder, Simon E., Zevnik, Branko, Prinz, Marco, Schell, Christoph, Young, George R., Kassiotis, George, Pasparakis, Manolis“…Mutations of the ADAR1 gene encoding an RNA deaminase cause severe diseases associated with chronic activation of type I interferon (IFN) responses, including Aicardi–Goutières syndrome and bilateral striatal necrosis(1–3). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1756por Sekheri, Meriem, Rizo-Téllez, Salma A., Othman, Amira, El Kebir, Driss, Filep, János G.“…Aberrant immune responses, including hyperresponsiveness to Toll-like receptor (TLR) ligands, underlie acute respiratory distress syndrome (ARDS). Type I interferons confer antiviral activities and could also regulate the inflammatory response, whereas little is known about their actions to resolve aberrant inflammation. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1757por Kelly, Robert F., Gonzaléz Gordon, Lina, Egbe, Nkongho F., Freeman, Emily J., Mazeri, Stella, Ngwa, Victor N., Tanya, Vincent, Sander, Melissa, Ndip, Lucy, Muwonge, Adrian, Morgan, Kenton L., Handel, Ian G., Bronsvoort, Barend M. D. C.Enlace del recurso
Publicado 2022
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1758por Li, Xueqian, Wang, Zhe, Zhou, Weiping, Fu, Xuanhe, Zhang, Yunpeng, Sun, Ye, Yang, Biao, Bai, Yuxin, Dai, Chunwei, Xu, Xiaolun, Cui, Fan, Zhao, Ying, Zhang, Yuping, Wang, Bengang, Li, Yingfang, Muramatsu, Masamichi, Wakae, Kousho, Liu, GuangyanEnlace del recurso
Publicado 2022
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1759“…Interferons (IFN) are antiviral cytokines with critical roles in regulating pathogens at epithelial barriers, but their capacity to restrict human enteric viruses has been incompletely characterized in part due to challenges in cultivating some viruses in vitro, particularly human norovirus. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1760por Gillezeau, Christina, Movva, Naimisha, van Gerwen, Maaike, Rabon-Stith, Karma, Shire, Norah, Brohawn, Philip Zachary, Taioli, Emanuela, Fryzek, Jon“…BACKGROUND: The role of interferon gamma (IFN-γ) expression in long-term survival has not been studied in patients with urinary bladder cancer (UBC). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto