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  1. 1761
    “…The major topics of this hypothesis paper are the disbalance between interferon and antibodies responses, HLA heterogeneity among the affected population, and increased proportion of cytotoxic CD4+ T cells polarization in relation to T follicular cells (Tfh) subtypes. …”
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    COVID-19 diverse outcomes: Aggravated reinfection, type I interferons and antibodies
  2. 1762
    “…Enrichment analysis showed that most of these genes were enriched in the interferon signalling pathway. Gene set enrichment analysis revealed that the sample was significantly enriched for expression of the interferon signalling pathway. …”
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    GBP2 acts as a member of the interferon signalling pathway in lupus nephritis
  3. 1763
    “…Antiviral type I interferons (IFN) produced in the early phase of viral infections effectively inhibit viral replication, prevent virus-mediated tissue damages and promote innate and adaptive immune responses that are all essential to the successful elimination of viruses. …”
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    Correlation between Type I Interferon Associated Factors and COVID-19 Severity
  4. 1764
    “…In human obesity, these global effects of interferon gamma to reduce regulatory T cells and diminish their function appear to instigate adipose inflammation and suppress adipocyte metabolism, leading to insulin resistance.…”
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    Interferon gamma mediates the reduction of adipose tissue regulatory T cells in human obesity
  5. 1765
    “…In a recent study in Nature Immunology, Musella et al. demonstrate that suboptimal type I interferon (IFN-I) signaling in tumors undergoing immunogenic cell death (ICD) facilitates the accumulation of cancer stem cells (CSCs) by triggering the epigenetic regulator lysine demethylase 1B (KDM1B). …”
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    Type I interferon induces cancer stem cells-mediated chemotherapy resistance
  6. 1766
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    Editorial: Type III interferons: Emerging roles beyond antiviral barrier defense
  7. 1767
    “…Since the discovery of interferon-tau (IFNT) over 30 years ago as the trophectodermal cytokine responsible for the maintenance of the maternal corpus luteum (CL) in ruminants, exhaustive studies have been conducted to identify genes and gene products related to CL maintenance. …”
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    Recent progress of interferon-tau research and potential direction beyond pregnancy recognition
  8. 1768
    por Suzuki, Youichi, Murakawa, Takeshi
    Publicado 2022
    “…Although the flaviviruses have a significant clinical impact, it has become apparent that flavivirus replication is restricted by cellular factors induced by the interferon (IFN) response, which are called IFN-stimulated genes (ISGs). …”
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    Restriction of Flaviviruses by an Interferon-Stimulated Gene SHFL/C19orf66
  9. 1769
    “…Interferon γ (IFN–γ) is now considered to be one of the key molecules in the regulation of innate and adaptive immunity. …”
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    Cloning, Exogenous Expression and Function Analysis of Interferon–γ from Gadus macrocephalus
  10. 1770
    “…Type I interferons (IFNs) are potent mediators of the innate immune response to viral infection. …”
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    Novel plant-derived recombinant human interferons with broad spectrum antiviral activity
  11. 1771
    “…A standard systemic therapy is not established. The efficacy of interferon-alpha (IFN-α) for GTS was described but the treatment periods were relatively short. …”
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    The potential influence of interferon-α on the growth of the growing teratoma: A case report
  12. 1772
    “…Interferon (IFN)-γ contributes to the pathogenesis of severe malaria; however, its mechanism remains unclear. …”
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    Increased interferon-γ levels and risk of severe malaria: a meta-analysis
  13. 1773
    “…By provoking inflammation, BCG can lead to the production of a factor called “interferon gamma” and an immune response that can eliminate the cancer. …”
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    The Urothelial Transcriptomic Response to Interferon Gamma: Implications for Bladder Cancer Prognosis and Immunotherapy
  14. 1774
    “…Another IFN formulation is interferon beta (IFN-β), which has been used for decades in the treatment of multiple sclerosis. …”
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    Recombinant Interferon-β in the Treatment of Polycythemia Vera and Related Neoplasms: Rationales and Perspectives
  15. 1775
    “…RV is one of the pathogens causing diarrhea in infants and young animals, and it induces the production of type I interferons (IFNs), which can trigger antiviral function by inducing the production of interferon–stimulated genes (ISGs). …”
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    Interferon–Inducible Transmembrane Protein 3 (IFITM3) Restricts Rotavirus Infection
  16. 1776
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    Severity of neonatal influenza infection is driven by type I interferon and oxidative stress
  17. 1777
    por Yang, Xu, Diaz, Valeria, Huang, Hu
    Publicado 2022
    “…Here, we report that the transcription factor interferon regulatory factor 1 (IRF1) plays critical roles in microglial activation and retinal inflammation by regulating pro- and anti-inflammatory gene expression. …”
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    The Role of Interferon Regulatory Factor 1 in Regulating Microglial Activation and Retinal Inflammation
  18. 1778
    por Park, Jung-Eun, Shin, Hyun-Jin
    Publicado 2022
    “…To understand the pathogenesis of the G2b PEDV, we examined the resistance of the G2b PEDV to interferon (IFN) and neutralizing antibodies, which are important for controlling PEDV infection. …”
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    Resistance of Field-Isolated Porcine Epidemic Diarrhea Virus to Interferon and Neutralizing Antibody
  19. 1779
    “…Pathway analysis of the RNA sequencing data for antidepressant responsiveness identified that hypercytokinemia- and interferon-related genes were increased in non-responders. …”
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    Interferon signaling and hypercytokinemia-related gene expression in the blood of antidepressant non-responders
  20. 1780
    “…By additional knockout MAVS or STAT1 in DHX9-deficient mice, we demonstrated that nucleic DHX9 plays a positive role in regulating interferon-stimulated gene (ISG) expression downstream of type I interferon. …”
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    Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes
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