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1781por Coelho, Matthew A., Cooper, Sarah, Strauss, Magdalena E., Karakoc, Emre, Bhosle, Shriram, Gonçalves, Emanuel, Picco, Gabriele, Burgold, Thomas, Cattaneo, Chiara M., Veninga, Vivien, Consonni, Sarah, Dinçer, Cansu, Vieira, Sara F., Gibson, Freddy, Barthorpe, Syd, Hardy, Claire, Rein, Joel, Thomas, Mark, Marioni, John, Voest, Emile E., Bassett, Andrew, Garnett, Mathew J.“…Interferon-γ (IFN-γ) signaling mediates host responses to infection, inflammation and anti-tumor immunity. …”
Publicado 2023
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1782por Zhang, Luhao, Zhang, Xin, Liao, Jiaming, Xu, Linting, Kang, Shaozhu, Chen, Hong, Sun, Mengshi, Wu, Siting, Xu, Zhuqing, Wei, Shina, Qin, Qiwei, Wei, Jingguang“…Silencing of EccGAS inhibited the replication of Singapore grouper iridovirus (SGIV) in grouper spleen (GS) cells and enhanced the expression of interferon-related factors. Furthermore, EccGAS inhibited EcSTING-mediated interferon response and interacted with EcSTING, EcTAK1, EcTBK1, and EcIRF3. …”
Publicado 2023
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1783por Ganesan, Sandhya, Alvarez, Natalie N., Steiner, Samuel, Fowler, Karen M., Corona, Abigail K., Roy, Craig R.“…It has been shown that gamma interferon (IFNγ)-stimulated host cells restrict C. burnetii replication by a mechanism that involves host IDO1 depletion of tryptophan. …”
Publicado 2023
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1784por Li, Yunqi, Lefebvre, Francois, Nakku-Joloba, Edith, Ronald, Allan, Gray, Glenda, de Bruyn, Guy, Kiarie, James, Celum, Connie, Cameron, Mark J, Lingappa, Jairam R, Mackelprang, Romel D“…We found PTPRC (encoding CD45 antigen) and interferon-response pathways had significantly higher expression among individuals who went on to become seropositive and thus may be a signature for increased acquisition risk.…”
Publicado 2023
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1785por Kuhl, Niklas, Linder, Andreas, Philipp, Nora, Nixdorf, Daniel, Fischer, Hannah, Veth, Simon, Kuut, Gunnar, Xu, Teng Teng, Theurich, Sebastian, Carell, Thomas, Subklewe, Marion, Hornung, Veit“…The cGAS‐STING (cyclic GMP‐AMP synthase‐stimulator of interferon genes) axis is the predominant DNA sensing system in cells of the innate immune system. …”
Publicado 2023
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1786por Lamsal, Apsana, Andersen, Sonja Benedikte, Johansson, Ida, Vietri, Marina, Bokil, Ansooya Avinash, Kurganovs, Natalie Jayne, Rylander, Felicia, Bjørkøy, Geir, Pettersen, Kristine, Giambelluca, Miriam S.“…RESULTS: We found that type I interferon (IFN-I) response was a key differentially regulated pathway between metastatic and non-metastatic cell lines and tumors. …”
Publicado 2023
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1787por Jeremiah, Nadia, Ferran, Hermine, Antoniadou, Konstantina, De Azevedo, Kevin, Nikolic, Jovan, Maurin, Mathieu, Benaroch, Philippe, Manel, Nicolas“…In innate immune cells, intracellular sensors such as cGAS-STING stimulate type I/III interferon (IFN) expression, which promotes antiviral defense and immune activation. …”
Publicado 2023
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1788por Hochhaus, Andreas, Burchert, Andreas, Saußele, Susanne, Baerlocher, Gabriela M, Mayer, Jiri, Brümmendorf, Tim H, La Rosee, Paul, Heim, Dominik, Krause, Stefan W, Le Coutre, Philipp, Fabisch, Christian, Rinke, Jenny, Lange, Thoralf, Fabarius, Alice, Lorch, Marcel, Hänel, Mathias, Stegelmann, Frank, Franke, Georg-Nikolaus, Radsak, Markus, Kunzmann, Volker, Himsel, Danny, Kohn, Denise, Lang, Thomas, Hehlmann, Rüdiger, Ernst, Thomas, Pfirrmann, MarkusEnlace del recurso
Publicado 2023
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1789“…These data seem to point out that natural immunity, which is up-regulated by endogenous or exogenous interferons, can play a significant role in surveillance against mouse leukaemic cells of retrovirus origin.…”
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1790por Huang, Chaohao, Chen, Shengchuan, Zhang, Tan, Li, Dapei, Huang, Zhonglin, Huang, Jian, Qin, Yanghua, Chen, Bicheng, Cheng, Genhong, Ma, Feng, Zhou, Mengtao“…We found that polyI:C triggers type I interferon (IFN) production and downstream IFN-α/β receptor (IFNAR)-dependent signaling, which play key roles in protecting the pancreas from inflammatory injury. …”
Publicado 2019
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1791por Wong, Hui Hui, Fung, To Sing, Fang, Shouguo, Huang, Mei, Le, My Tra, Liu, Ding Xiang“…Severe acute respiratory syndrome coronavirus (SARS-CoV) is an inefficient inducer of interferon (IFN) response. It expresses various proteins that effectively circumvent IFN production at different levels via distinct mechanisms. …”
Publicado 2018
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1792“…OBJECTIVES: We will evaluate the efficacy and safety of favipiravir and interferon beta-1a compared to lopinavir/ritonavir and interferon beta-1a in patients with confirmed COVID-19, who are moderately ill. …”
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1793por Alavi Darazam, Ilad, Hatami, Firouze, Mahdi Rabiei, Mohammad, Amin Pourhoseingholi, Mohamad, Shabani, Minoosh, Shokouhi, Shervin, Mardani, Masoud, Moradi, Omid, Javandoust Gharehbagh, Farid, Mirtalaee, Nasrinsadat, Negahban, Halimeh, Amirdosara, Mahdi, Zangi, Masoud, Hajiesmaeili, Mohammadreza, Kazempour, Muhanna, Shafigh, Navid“…INTRODUCTION: Coronavirus disease 2019 (COVID-19) has been a serious obstacle in front of public health. Interferon-beta 1a (IFN-β 1a) has been used to treat patients with COVID-19. …”
Publicado 2021
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1794por Dietz, Nicholas, Mufti, Zarmina, Yousaf, Muhammed, Brown, Randal, Counts, Christopher, Bjurström, Martin F., Williams, Brian J., Robertson, David“…CASE PRESENTATION: A 54-year-old female with past medical history of well-controlled multiple sclerosis on interferon-beta since 2013, presented with witnessed tonic colonic seizure. …”
Publicado 2021
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1795por Casano, Anna Beatrice, Barile, Vittoria Lucia, Menchetti, Laura, Guelfi, Gabriella, Brecchia, Gabriele, Agradi, Stella, De Matteis, Giovanna, Scatà, Maria Carmela, Grandoni, Francesco, Barbato, Olimpia“…ABSTRACT: The objective of this study was to analyze interferon-stimulated genes (ISGs) and interferon tau (IFNt) gene expression in peripheral blood leukocytes during the peri-implantation period and until 40 days of pregnancy in buffalo cows. …”
Publicado 2022
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1796“…High-throughput sequencing of tRNA pools explains the reduced inhibition of replication by interferon: the levels of some tRNAs differ between interferon-treated and untreated human cells, and evolution of the codon usage of H3N2 PB1 mRNA is skewed toward interferon-altered human tRNA pools. …”
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1799por Qin, Huifang, Wang, Yiting, Huang, Liwen, Huang, Yan, Ye, Jing, Liang, Guijin, Zhou, Chongxing, Liang, Dabin, Liang, Xiaoyan, Zhao, Yanlin, Lin, MeiEnlace del recurso
Publicado 2023
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1800por Xiong, Xinlin, Duan, Zonggang, Zhou, Haiyan, Huang, Guangwei, Niu, Li, Luo, Zhenhua, Li, Wei“…BACKGROUND: The association of Apolipoprotein A‐I (APOAI) with T cell subsets and interferon‐ү (IFN‐γ) in patients with coronary artery disease (CAD) has been not reported. …”
Publicado 2023
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