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  1. 1901
    “…Here, we present a bioinformatic analysis of HCV-1a populations isolated from 23 children with chronic hepatitis C (CHC) subjected to interferon–ribavirin therapy. The structures of the viral quasispecies were established based on a 132-amino-acid sequence derived from E1/E2 protein, including hypervariable region 1 (HVR1). …”
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    Hepatitis C virus quasispecies in chronically infected children subjected to interferon–ribavirin therapy
  2. 1902
    “…The current standard treatment for chronic hepatitis (CH) C combines pegylated interferon (IFN) and ribavirin, and is less than ideal due to undesirable effects. …”
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    Hepatic microRNA expression is associated with the response to interferon treatment of chronic hepatitis C
  3. 1903
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    Hijacking of the Pleiotropic Cytokine Interferon-γ by the Type III Secretion System of Yersinia pestis
  4. 1904
    por Kim, S. Y., Houh, W.
    Publicado 1987
    “…Gamma interferon (gamma-IFN), a lymphokine produced by activated T lymphocytes, has a variety of effects on target cell. …”
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    Gamma interferon modulates epidermal cell proliferation and mixed epidermal cell-lymphocyte reaction.
  5. 1905
    “…Polymyositis is a rare complication of interferon alpha treatment as a result of immune-modulating role of the drug itself. …”
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    A case of polymyositis with dilated cardiomyopathy associated with interferon alpha treatment for hepatitis B.
  6. 1906
    por Ye, Junqiang, Maniatis, Tom
    Publicado 2011
    “…The production of type I interferons (IFNs) in response to viral infections is critical for antiviral immunity. …”
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    Negative Regulation of Interferon-β Gene Expression during Acute and Persistent Virus Infections
  7. 1907
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    Innate and adaptive anti-viral immune responses in MS patients treated with interferon-beta
  8. 1908
    “…This study tested the hypothesis that a set of predominantly myeloid restricted receptors (F4/80, CD36, Dectin-1, CD200 receptor and mannan binding lectins) and the broadly expressed CD200 played a role in a key function of plasmacytoid DC (pDC), virally induced type I interferon (IFN) production. The Dectin-1 ligands zymosan, glucan phosphate and the anti-Dectin-1 monoclonal antibody (mAb) 2A11 had no effect on influenza virus induced IFNα/β production by murine splenic pDC. …”
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    The role of myeloid receptors on murine plasmacytoid dendritic cells in induction of type I interferon
  9. 1909
    por Ke, Wan-Sheng, Hwang, Yuchi, Lin, Eugene
    Publicado 2010
    “…Chronic hepatitis C (CHC) patients often stop pursuing interferon-alfa and ribavirin (IFN-alfa/RBV) treatment because of the high cost and associated adverse effects. …”
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    Pharmacogenomics of drug efficacy in the interferon treatment of chronic hepatitis C using classification algorithms
  10. 1910
    “…METHODS: We reviewed the clinical records of two patients who were diagnosed with VKH-like disease during combined interferon-α (IFNα) and ribavirin treatment. RESULTS: Interruption of IFNα and ribavirin treatment in association with oral corticosteroids resulted in a favorable visual outcome in the case of diffuse retinal detachment (case 1). …”
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    Serous Retinal Detachments Complicating Interferon-α and Ribavirin Treatment in Patients with Hepatitis C
  11. 1911
    “…BACKGROUND: Neuropsychiatric adverse effects of interferon (IFN) alpha are well known. There is little clinically relevant research on animal models of depression with recombinant human IFN alpha 2b (rhIFN-α2b). …”
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    Development of a murine animal model of depression for repeated dosing with human interferon alpha
  12. 1912
    “…We have investigated the ability of NSDV to antagonise the induction and actions of interferon. Both pathogenic and apathogenic isolates could actively inhibit the induction of type 1 interferon, and also blocked the signalling pathways of both type 1 and type 2 interferons. …”
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    Inhibition of Interferon Induction and Action by the Nairovirus Nairobi Sheep Disease Virus/Ganjam Virus
  13. 1913
    por Singal, Ashwani Kumar
    Publicado 2010
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    Type of Pegylated Interferon Matters: Another Milestone in the Treatment of Hepatitis C Virus Infection
  14. 1914
    “…Combination therapy with pegylated interferon (PEG-IFN) and Ribavirin is the treatment of choice for CHC. …”
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    Interferon-Alpha Induced and Ribavirin Induced Thyroid Dysfunction in Patients with Chronic Hepatitis C
  15. 1915
    “…BACKGROUND: Interferon based therapy is used to eradicate the Hepatitis C Virus from the bodies of the infected individuals. …”
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    Response rates of standard interferon therapy in chronic HCV patients of Khyber Pakhtunkhwa (KPK)
  16. 1916
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    New reporter cell clones to determine the biological activity of human type I interferons
  17. 1917
    “…Synthesis of interferon-β (IFN-β) is an innate response to cytoplasmic infection with bacterial pathogens. …”
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    Both TLR2 and TRIF Contribute to Interferon-β Production during Listeria Infection
  18. 1918
    “…Effective antiviral immunity depends on the ability of infected cells or cells triggered with virus-derived nucleic acids to produce type I interferon (IFN), which activates transcription of numerous antiviral genes. …”
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    Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
  19. 1919
    “…As a result, viruses may persist in host and develop chronic infections. Type I interferons (IFN-α/β) are among the most potent antiviral cytokines triggered by viral infections. …”
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    Interplay between Interferon-Mediated Innate Immunity and Porcine Reproductive and Respiratory Syndrome Virus
  20. 1920
    “…BACKGROUND: There is an inverse relationship between febrile infection and the risk of malignancies. Interferon gamma (IFN-γ) plays an important role in fever induction and its expression increases with incubation at fever-range temperatures. …”
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    Joint Effects of Febrile Acute Infection and an Interferon-γ Polymorphism on Breast Cancer Risk
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