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    por Secombes, Chris J., Zou, Jun
    Publicado 2017
    “…The earliest jawed vertebrates (Gnathostomes) would likely have had interferon (IFN) genes, since they are present in extant cartilaginous fish (sharks and rays) and bony fish (lobe-finned and ray-finned fish, the latter consisting of the chondrostei, holostei, and teleostei), as well as in tetrapods. …”
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    por Jahiel, Rene I.
    Publicado 1970
    Materias: “…Interferon and Interferon Inducers in Disease…”
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    “…Major players of the innate and adaptive responses are interferons. Here, we review their roles and the signaling pathways involved in their production and protection against infection and induced immunopathologies.…”
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    por Taylor, Milton W.
    Publicado 2014
    “…Interferon was discovered by Alick Isaacs and Jean Lindenmann in 1957. …”
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    “…The therapeutic effect of interferon will be enhanced when combined with other drugs. …”
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    Publicado 2007
    “…Interferon (IFN)-α has reigned supreme for decades as biotech's blockbuster antiviral. …”
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    “…New interferons (IFNs) include members of the type I IFN family, such as IFN epsilon (IFNε), IFN tau, IFN omega, and IFN kappa, as well as the type III IFN family, also known as the IFN lambdas. …”
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    “…Differential signaling of the type I interferon receptor (IFNAR) has been correlated with the ability of its subunit, IFNAR1, to differentially recognize a large spectrum of different ligands, which involves intricate conformational re-arrangements of multiple interacting domains. …”
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  17. 17
    por Crow, Mary K, Rönnblom, Lars
    Publicado 2018
    “…An international summit on interferon (IFN) in inflammatory diseases, held in Gaithersburg, Maryland, USA (4–5 May 2017), united 22 internationally renowned clinicians and scientists with backgrounds in basic science, translational science and clinical medicine. …”
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    por Baron, Samuel
    Publicado 1970
    Materias: “…Interferon and Interferon Inducers in Disease…”
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