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  1. 2961
    “…BACKGROUND: Combining different sources of knowledge to build improved structure activity relationship models is not easy owing to the variety of knowledge formats and the absence of a common framework to interoperate between learning techniques. Most of the current approaches address this problem by using consensus models that operate at the prediction level. …”
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    Self organising hypothesis networks: a new approach for representing and structuring SAR knowledge
  2. 2962
    “…An ideal developing environment for NGS should be modular (with a native library interface), scalable in computational methods (i.e. serial, multithread, distributed), transparent (platform-independent), interoperable (with external software interface), and usable (via an intuitive graphical user interface). …”
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    Visual programming for next-generation sequencing data analytics
  3. 2963
    “…Recently, an international initiative interested in scholarly data publishing proposed that all scientific data should be “FAIR”—Findable, Accessible, Interoperable, and Reusable. In this work, we describe the process of migrating a database of notable relevance to the plant sciences—the Pathogen-Host Interaction Database (PHI-base)—to a form that conforms to each of the FAIR Principles. …”
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    Publishing FAIR Data: An Exemplar Methodology Utilizing PHI-Base
  4. 2964
    “…RESULTS: This paper comprehensively describes the efficient and rational combination and interoperation of these technologies and methods through Mining Minds, while meeting the essential requirements posed by a framework for personalized health and wellness support. …”
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    The Mining Minds digital health and wellness framework
  5. 2965
    “…Moreover, the low reproducibility and the possible interoperator variability of the method raised concerns.…”
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    Evaluation of electrical impedance spectroscopy as an adjunct to dermoscopy in short-term monitoring of atypical melanocytic lesions
  6. 2966
    “…However, current multi-jurisdictional pathogen surveillance and investigation efforts are complicated by time-consuming data re-entry, curation and integration of contextual information owing to a lack of interoperable standards and inconsistent reporting. A solution to these challenges is the use of ‘ontologies’ - hierarchies of well-defined and standardized vocabularies interconnected by logical relationships. …”
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    Context Is Everything: Harmonization of Critical Food Microbiology Descriptors and Metadata for Improved Food Safety and Surveillance
  7. 2967
    “…CONCLUSIONS: Through a combination of streamlined data acquisition, interoperable representation of dataset collections, and customizable statistical analysis with guided setup and interpretation, the GSuite HyperBrowser represents a first comprehensive solution for integrative analysis of track collections across the genome and epigenome. …”
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    GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
  8. 2968
    “…BACKGROUND AND OBJECTIVES: Although endoscopic ultrasonography (EUS) features and criteria have been described in chronic pancreatitis, interoperator variability and ease of adoption limit their usefulness. …”
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    HPB PLENARY: OR-HPB-03: Defining endoscopic ultrasonography features chronic pancreatitis in asians – a multicenter validation study
  9. 2969
    “…The openEHR specifications are designed to support implementation of flexible and interoperable Electronic Health Record (EHR) systems. …”
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    ORBDA: An openEHR benchmark dataset for performance assessment of electronic health record servers
  10. 2970
    “…The Brain-CODE system architecture provides the technical capabilities to support (1) consolidated data management to securely capture, monitor and curate data, (2) privacy and security best-practices, and (3) interoperable and extensible systems that support harmonization, integration, and query across diverse data modalities and linkages to external data sources. …”
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    Brain-CODE: A Secure Neuroinformatics Platform for Management, Federation, Sharing and Analysis of Multi-Dimensional Neuroscience Data
  11. 2971
    “…To help refine the range of Gal4 lines, we developed an intersectional genetic AND operator. Interoperable with Gal4, the new system’s key component is a fusion protein in which the DNA-binding domain of Gal4 has been replaced with a zinc finger domain with a different DNA-binding specificity. …”
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    A zinc-finger fusion protein refines Gal4-defined neural circuits
  12. 2972
    “…Based on such an interoperation, Illumina’s Infinium platform is quite amenable to usage in a clinical setting for diagnostic work. …”
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    Establishing a stable, repeatable platform for measuring changes in sperm DNA methylation
  13. 2973
    “…We envision the development of an integrated system composed of an aggregation of sub-systems interoperating with the aim of achieving an overarching functionality (in this case‚ better CAD, CARP, and CABP). …”
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    Radiomics: a critical step towards integrated healthcare
  14. 2974
    “…We propose ‘term sets’, an equivalent alternative to code sets that are findable, accessible, interoperable and reusable. MATERIALS AND METHODS: We describe a new code set representation, consisting of natural language inclusion and exclusion terms (term sets), and explain its relationship to code sets. …”
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    Term sets: A transparent and reproducible representation of clinical code sets
  15. 2975
    “…It exists to help make computable biomedical knowledge findable, accessible, interoperable, and reusable. KORO is currently being used to further develop and improve computable knowledge infrastructure for learning health systems.…”
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    The Knowledge Object Reference Ontology (KORO): A formalism to support management and sharing of computable biomedical knowledge for learning health systems
  16. 2976
    “…A prototype Rice Galaxy compliant to Open Access, Open Data, and Findable, Accessible, Interoperable, and Reproducible principles is also presented. …”
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    Rice Galaxy: an open resource for plant science
  17. 2977
    “…It furthers the TBPP goals to provide a web-enabled analytics platform to countries with a high burden of multidrug-resistant TB (MDR-TB) but limited IT resources and inaccessible data, and enables the reusability of data, in conformity with the NIH’s Findable, Accessible, Interoperable, and Reusable (FAIR) principles. TB DEPOT provides access to “analysis-ready” data and the ability to generate and test complex clinically-oriented hypotheses instantaneously with minimal statistical background and data processing skills. …”
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    TB DEPOT (Data Exploration Portal): A multi-domain tuberculosis data analysis resource
  18. 2978
    “…INTRODUCTION: Health information generated by health care encounters, research enterprises, and public health is increasingly interoperable and shareable across uses and users. This paper examines the US public’s willingness to be a part of multi-user health information networks and identifies factors associated with that willingness. …”
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    Willingness to Participate in Health Information Networks with Diverse Data Use: Evaluating Public Perspectives
  19. 2979
    “…This collaborative project is based on interoperable Web-based databases, comprising 7 regional and independent but uniformly organized chapters, namely Africa, Asia, Australia, Europe, North America, South America, and the United Kingdom. …”
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    ADPedKD: A Global Online Platform on the Management of Children With ADPKD
  20. 2980
    “…Data collection was interoperable only in Georgia without integrated analysis. …”
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    Implementation of the One Health approach to fight arbovirus infections in the Mediterranean and Black Sea Region: Assessing integrated surveillance in Serbia, Tunisia and Georgia
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