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77061por Hauser, Robert A., Espay, Alberto J., Ellenbogen, Aaron L., Fernandez, Hubert H., Isaacson, Stuart H., LeWitt, Peter A., Ondo, William G., Pahwa, Rajesh, Schwarz, Johannes, Stocchi, Fabrizio, Zeitlin, Leonid, Banisadr, Ghazal, Fisher, Stanley, Visser, Hester, D’Souza, Richard“…IMPORTANCE: Levodopa has a short half-life and a limited window of opportunity for absorption in the proximal small intestine. IPX203 is an oral, extended-release formulation of carbidopa-levodopa developed to address these limitations. …”
Publicado 2023
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77062por Rani, Sundas, Sørensen, Martin Tang, Estellé, Jordi, Noel, Samantha Joan, Nørskov, Natalja, Krogh, Uffe, Foldager, Leslie, Højberg, Ole“…Piglets were sacrificed after 9 and 35 days of treatment, and stomach, small intestine, cecum, and colon digesta were analyzed for glyphosate, aminomethylphosphonic acid (AMPA), organic acids, pH, dry matter content, and microbiota composition. …”
Publicado 2023
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77063por Pena, Omar Manuel, Murphy, Kevin, Long, Nathan, Lascano, Gustavo J., Jenkins, Thomas C., Aguerre, Matías J.“…Thus, only a small percentage of the fatty acids contained in the cow’s diet reach the intestine and are further incorporated into milk and meat. …”
Publicado 2023
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77064“…Background: Metformin, commonly used medication to treat Type II Diabetes Mellitus (DM) improves insulin sensitivity, reduces glucose production in liver and absorption by intestines. Type II DM patients often have higher BMI with increased incidence of sleep apnea. …”
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77065SKCG-1: a new candidate growth regulatory gene at chromosome 11q23.2 in human sporadic Wilms tumours“…The transcript of SKCG-1 was abundantly present in brain, kidney, liver, testis, salivary gland, foetal brain, foetal liver, whereas relatively lower expression in heart, stomach, prostate and no expression in spleen, colon, lung, small intestine, muscle, adrenal gland, uterus, skin, PBL, and bone marrow was detected. …”
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77066“…C. difficile associated diarrhea (CDAD) is manifested by severe inflammation and colitis, mostly due to the release of two exotoxins by C. difficile causing destruction of epithelial cells in the intestine. The aim of this study was to determine the effect of probiotic bacteria Lactobacillus delbrueckii ssp. bulgaricus B-30892 (LDB B-30892) on C. difficile-mediated cytotoxicity using Caco-2 cells as a model. …”
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77067“…BACKGROUND: Inflammatory bowel diseases (IBD) refer to a group of inflammatory conditions concerning colon and small intestine, which cause socially uncomfortable symptoms and often are associated with an increased risk of colon cancer. …”
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77068por Dang, Zhisheng, Feng, Jinchao, Yagi, Kinpei, Sugimoto, Chihiro, Li, Wei, Oku, Yuzaburo“…Immunization with rEm-TSP3-FBP provoked significantly stronger IgA antibody responses in intestine (p<0.05), lung (p<0.001) and spleen (p<0.001) compared to those by rEm-TSP3+CpG. …”
Publicado 2012
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77069por Ashour, Mohamed-Bassem, Ragheb, Didair A., El-Sheikh, El-Sayed A., Gomaa, El-Adarosy A., Kamita, Shizuo G., Hammock, Bruce D.“…Immunohistochemical observation of tissues from stomach, intestine, liver, kidney, brain, spleen, and lung also showed slight changes. …”
Publicado 2007
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77070por Zechmann, Christian M., Afshar-Oromieh, Ali, Armor, Tom, Stubbs, James B., Mier, Walter, Hadaschik, Boris, Joyal, John, Kopka, Klaus, Debus, Jürgen, Babich, John W., Haberkorn, Uwe“…RESULTS: I-124-MIP-1095 PET/CT images showed excellent tumor uptake and moderate uptake in liver, proximal intestine and within a few hours post-injection also in the kidneys. …”
Publicado 2014
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77071por Pfister, Joachim, Summer, Dominik, Rangger, Christine, Petrik, Milos, von Guggenberg, Elisabeth, Minazzi, Paolo, Giovenzana, Giovanni B., Aloj, Luigi, Decristoforo, Clemens“…Biodistribution in normal mice with the [(177)Lu]-AAZTA-MG showed a considerable uptake in intestine (7.3 % ID/g) and liver (1.5 % ID/g). CONCLUSION: Overall, AAZTA showed interesting properties as bifunctional chelator for peptides providing mild radiolabelling conditions for both (68)Ga and trivalent metals having advantages over the currently used chelator DOTA. …”
Publicado 2015
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77072por Yang, Run-Wei, Zeng, Ying-Yue, Wei, Wen-Ting, Cui, Yan-Mei, Sun, Hui-Ying, Cai, Yue-Long, Nian, Xin-Xin, Hu, Yun-Teng, Quan, Yu-Ping, Jiang, Sheng-Lu, Wang, Meng, Zhao, Ya-Li, Qiu, Jun-Feng, Li, Ming-Xuan, Zhang, Jia-Huan, He, Mei-Rong, Liang, Li, Ding, Yan-Qing, Liao, Wen-Ting“…METHODS: Gene expression profiles were analyzed in The Cancer Genome Atlas (TCGA) microarray dataset of 41 normal colorectal intestine tissues and 465 CRC tissues. Western blot and Real-time Quantitative PCR (RT-qPCR) were respectively performed to detect protein and mRNA expression in 8 pairs of CRC tissue and matched adjacent normal mucosa. …”
Publicado 2016
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77073“…Lipoma locations: antrum-17, body-and-antrum-4, antrum-intussuscepting-into-small-intestine-3, body-2, fundus-1, and unspecified-5. Intramural locations included submucosal-22, subserosal-2, and unspecified-8. …”
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77074por Moreira, Otacilio C., Verly, Thaiane, Finamore-Araujo, Paula, Gomes, Suzete A. O., Lopes, Catarina M., de Sousa, Danielle M., Azevedo, Lívia R., da Mota, Fabio F., d’Avila-Levy, Claudia M., Santos-Mallet, Jacenir R., Britto, Constança“…In addition, a wide range distribution of parasite load, varying from 8.05 × 10(-2) to 6.31 × 10(10) was observed with a median of 2.29 × 10(3) T. cruzi/intestine units. When parasite load was analyzed by triatomine species, a significantly higher median was found for Panstrongylus lutzi in comparison with Triatoma brasiliensis. …”
Publicado 2017
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77075por Dowling, Matthew, Samuelson, Jonathan, Fadl-Alla, Bahaa, Pondenis, Holly C., Byrum, Mark, Barger, Anne M., Fan, Timothy M.“…As predicted by human protein atlas data, PSMA’s expression was comparably identified at substantial levels in select normal canine tissues including kidney, liver, and intestine. In young healthy pet dogs, PSMA amplicons could not be identified in circulating whole blood yet were detectable in hemorrhagic effusions collected from pet dogs with confirmed cHSA or PSMA-expressing cancer. …”
Publicado 2019
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77076por Schottelius, Margret, Wurzer, Alexander, Wissmiller, Katharina, Beck, Roswitha, Koch, Maximilian, Gorpas, Dimitrios, Notni, Johannes, Buckle, Tessa, van Oosterom, Matthias N., Steiger, Katja, Ntziachristos, Vasilis, Schwaiger, Markus, van Leeuwen, Fijs W.B., Wester, Hans-Jürgen“…Tumor-to-background ratios of 2.1, 5.2, 9.6, and 9.6 for blood, liver, intestines, and muscle, respectively, at 1 h after injection led to excellent imaging contrast in (68)Ga-PSMA-I&F PET and in intraoperative fluorescence imaging. …”
Publicado 2019
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77077por Button, Emily B., Boyce, Guilaine K., Wilkinson, Anna, Stukas, Sophie, Hayat, Arooj, Fan, Jianjia, Wadsworth, Brennan J., Robert, Jerome, Martens, Kris M., Wellington, Cheryl L.“…In mice, deficiency of apoA-I, the primary protein component of HDL, increases CAA and cognitive dysfunction, whereas overexpression of apoA-I from its native promoter in liver and intestine has the opposite effect and lessens neuroinflammation. …”
Publicado 2019
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77078por Hohberg, Melanie, Kobe, Carsten, Krapf, Philipp, Täger, Philipp, Hammes, Jochen, Dietlein, Felix, Zlatopolskiy, Boris D., Endepols, Heike, Wild, Markus, Neubauer, Stephan, Heidenreich, Axel, Neumaier, Bernd, Drzezga, Alexander, Dietlein, Markus“…RESULTS: Physiologic radiotracer accumulation was observed in the salivary and lacrimal glands, liver, spleen, and intestines, in a pattern resembling the distribution known from other PSMA-tracers with excretion via urinary and biliary pathways. …”
Publicado 2019
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77079por Gojkovic, Slaven, Krezic, Ivan, Vrdoljak, Borna, Malekinusic, Dominik, Barisic, Ivan, Petrovic, Andreja, Horvat Pavlov, Katarina, Kolovrat, Marijan, Duzel, Antonija, Knezevic, Mario, Kasnik Kovac, Katarina, Drmic, Domagoj, Batelja Vuletic, Lovorka, Kokot, Antonio, Boban Blagaic, Alenka, Seiwerth, Sven, Sikiric, Predrag“…In addition, there was reduced pathology of the lungs (severe capillary congestion) and liver (dilated central veins and terminal portal venules), decreased intestine hemorrhagic lesions (substantial capillary congestion, submucosal edema and architecture loss), and increased liver and spleen weight. …”
Publicado 2020
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77080“…Thus, we hypothesize that the expression of sialic acid O-acetylesterases with a broad specificity could be an advantage in competition with the gut microbiota for nutrients and facilitate EHEC colonization in the human large intestine.…”
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