A MYC/GCN2/eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer

por Schmidt, Stefanie, Gay, David, Uthe, Friedrich Wilhelm, Denk, Sarah, Paauwe, Madelon, Matthes, Niels, Diefenbacher, Markus Elmar, Bryson, Sheila, Warrander, Fiona Clare, Erhard, Florian, Ade, Carsten Patrick, Baluapuri, Apoorva, Walz, Susanne, Jackstadt, Rene, Ford, Catriona, Vlachogiannis, Georgios, Valeri, Nicola, Otto, Christoph, Schülein-Völk, Christina, Maurus, Katja, Schmitz, Werner, Knight, John Raymond Philip, Wolf, Elmar, Strathdee, Douglas, Schulze, Almut, Germer, Christoph-Thomas, Rosenwald, Andreas, Sansom, Owen James, Eilers, Martin, Wiegering, Armin
Publicado 2019

Comparative Analyses of Vertebrate Gut Microbiomes Reveal Convergence between Birds and Bats

por Song, Se Jin, Sanders, Jon G., Delsuc, Frédéric, Metcalf, Jessica, Amato, Katherine, Taylor, Michael W., Mazel, Florent, Lutz, Holly L., Winker, Kevin, Graves, Gary R., Humphrey, Gregory, Gilbert, Jack A., Hackett, Shannon J., White, Kevin P., Skeen, Heather R., Kurtis, Sarah M., Withrow, Jack, Braile, Thomas, Miller, Matthew, McCracken, Kevin G., Maley, James M., Ezenwa, Vanessa O., Williams, Allison, Blanton, Jessica M., McKenzie, Valerie J., Knight, Rob
Publicado 2020

Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory study

por Smyth, L. J., Kilner, J., Nair, V., Liu, H., Brennan, E., Kerr, K., Sandholm, N., Cole, J., Dahlström, E., Syreeni, A., Salem, R. M., Nelson, R. G., Looker, H. C., Wooster, C., Anderson, K., McKay, G. J., Kee, F., Young, I., Andrews, D., Forsblom, C., Hirschhorn, J. N., Godson, C., Groop, P. H., Maxwell, A. P., Susztak, K., Kretzler, M., Florez, J. C., McKnight, A. J.
Publicado 2021

Prospective Case-Control Study of Cardiovascular Abnormalities 6 Months Following Mild COVID-19 in Healthcare Workers

por Joy, George, Artico, Jessica, Kurdi, Hibba, Seraphim, Andreas, Lau, Clement, Thornton, George D., Oliveira, Marta Fontes, Adam, Robert Daniel, Aziminia, Nikoo, Menacho, Katia, Chacko, Liza, Brown, James T., Patel, Rishi K., Shiwani, Hunain, Bhuva, Anish, Augusto, Joao B., Andiapen, Mervyn, McKnight, Aine, Noursadeghi, Mahdad, Pierce, Iain, Evain, Timothée, Captur, Gabriella, Davies, Rhodri H., Greenwood, John P., Fontana, Marianna, Kellman, Peter, Schelbert, Erik B., Treibel, Thomas A., Manisty, Charlotte, Moon, James C.
Publicado 2021

Antigen-driven EGR2 expression is required for exhausted CD8(+) T cell stability and maintenance

por Wagle, Mayura V., Vervoort, Stephin J., Kelly, Madison J., Van Der Byl, Willem, Peters, Timothy J., Martin, Ben P., Martelotto, Luciano G., Nüssing, Simone, Ramsbottom, Kelly M., Torpy, James R., Knight, Deborah, Reading, Sinead, Thia, Kevin, Miosge, Lisa A., Howard, Debbie R., Gloury, Renee, Gabriel, Sarah S., Utzschneider, Daniel T., Oliaro, Jane, Powell, Jonathan D., Luciani, Fabio, Trapani, Joseph A., Johnstone, Ricky W., Kallies, Axel, Goodnow, Christopher C., Parish, Ian A.
Publicado 2021

The National Conference on Health Disparities Student Research Forum

por Ford, Marvella E., Malek, Angela M., Martino, Erica, Abraham-Hilaire, Latecia, Ariyo, Oluwole, Burshell, Dana, Callwood, Gloria, Campbell, Laura, Cannady, Kimberly, Chavis, Courtney, Crawford, Brittney, Edwards, Andie, Findlay, Victoria, Finley, Rita, Greenaway, Chamiere, Hazelton, Tonya, Hill, Monique, Howard, Marion, Knight, Kendrea D., Lopez-Littleton, Vanessa, Moore, Lloyd, Randle, Diandra, Rivers, David E., Salley, Judith D., Seabrook, Terry, Slaughter, Sabra, Stukes, James B., Thorpe, Roland J., Ragster, LaVerne
Publicado 2021

RNA Sequencing of Lens Capsular Epithelium Implicates Novel Pathways in Pseudoexfoliation Syndrome

por Mullany, Sean, Marshall, Henry, Zhou, Tiger, Thomson, Daniel, Schmidt, Joshua M., Qassim, Ayub, Knight, Lachlan S. W., Hollitt, Georgina, Berry, Ella C., Nguyen, Thi, To, Minh-Son, Dimasi, David, Kuot, Abraham, Dubowsky, Joshua, Fogarty, Rhys, Sun, Michelle, Chehade, Luke, Kuruvilla, Shilpa, Supramaniam, Devaraj, Breen, James, Sharma, Shiwani, Landers, John, Lake, Stewart, Mills, Richard A., Hassall, Mark M., Chan, Weng O., Klebe, Sonja, Souzeau, Emmanuelle, Siggs, Owen M., Craig, Jamie E.
Publicado 2022

Genome Sequence of CaiB, a DR Cluster Actinobacteriophage That Infects Gordonia rubripertincta

por Welsh, Bienna, Abdalla, Nader M., Aldana, Esteban, Alvarado Fernandez, Veronica M., Arenales Salgado de Oliveira, Bruna, Fakhre, Diane, Haymond, Amelia J., Helton, Katelyn M., Kanchibhatta, Aditi, Knight, Jahwanza, Marshall, Sydney, Martinez, Maomi Laine N., Merkher, Arielle, Morrow, Savannah E., Nguyen, Katie P., Patel, Jahanvi J., Patel, Somesh R., Rayala, Pravalika, Ruiz-Houston, Kira M., Satardekar, Aarya P., Shaikh, Shifa M., Terron Osorio, Adrian E., Weitz, Rachel C., Otero, Louis, Pollenz, Richard S.
Publicado 2022

Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales

por Knight, Rochelle, Walker, Venexia, Ip, Samantha, Cooper, Jennifer A., Bolton, Thomas, Keene, Spencer, Denholm, Rachel, Akbari, Ashley, Abbasizanjani, Hoda, Torabi, Fatemeh, Omigie, Efosa, Hollings, Sam, North, Teri-Louise, Toms, Renin, Jiang, Xiyun, Angelantonio, Emanuele Di, Denaxas, Spiros, Thygesen, Johan H., Tomlinson, Christopher, Bray, Ben, Smith, Craig J., Barber, Mark, Khunti, Kamlesh, Davey Smith, George, Chaturvedi, Nishi, Sudlow, Cathie, Whiteley, William N., Wood, Angela M., Sterne, Jonathan A.C.
Publicado 2022

Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Antigen in the Blood as a Diagnostic Test for Infection and Infectious Viral Shedding

por Mathur, Sujata, Davidson, Michelle C, Anglin, Khamal, Lu, Scott, Goldberg, Sarah A, Garcia-Knight, Miguel, Tassetto, Michel, Zhang, Amethyst, Romero, Mariela, Pineda-Ramirez, Jesus, Diaz-Sanchez, Ruth, Rugart, Paulina, Chen, Jessica Y, Donohue, Kevin, Shak, Joshua R, Chenna, Ahmed, Winslow, John W, Petropoulos, Christos J, Yee, Brandon C, Lambert, Jeremy, Glidden, David V, Rutherford, George W, Deeks, Steven G, Peluso, Michael J, Andino, Raul, Martin, Jeffrey N, Kelly, J Daniel
Publicado 2022

Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease

por Smyth, Laura J., Dahlström, Emma H., Syreeni, Anna, Kerr, Katie, Kilner, Jill, Doyle, Ross, Brennan, Eoin, Nair, Viji, Fermin, Damian, Nelson, Robert G., Looker, Helen C., Wooster, Christopher, Andrews, Darrell, Anderson, Kerry, McKay, Gareth J., Cole, Joanne B., Salem, Rany M., Conlon, Peter J., Kretzler, Matthias, Hirschhorn, Joel N., Sadlier, Denise, Godson, Catherine, Florez, Jose C., Forsblom, Carol, Maxwell, Alexander P., Groop, Per-Henrik, Sandholm, Niina, McKnight, Amy Jayne
Publicado 2022

Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection

por Mentzer, Alexander J., O’Connor, Daniel, Bibi, Sagida, Chelysheva, Irina, Clutterbuck, Elizabeth A., Demissie, Tesfaye, Dinesh, Tanya, Edwards, Nick J., Felle, Sally, Feng, Shuo, Flaxman, Amy L., Karp-Tatham, Eleanor, Li, Grace, Liu, Xinxue, Marchevsky, Natalie, Godfrey, Leila, Makinson, Rebecca, Bull, Maireid B., Fowler, Jamie, Alamad, Bana, Malinauskas, Tomas, Chong, Amanda Y., Sanders, Katherine, Shaw, Robert H., Voysey, Merryn, Snape, Matthew D., Pollard, Andrew J., Lambe, Teresa, Knight, Julian C.
Publicado 2022

Progression of echocardiographic parameters and prognosis in transthyretin cardiac amyloidosis

por Chacko, Liza, Karia, Nina, Venneri, Lucia, Bandera, Francesco, Passo, Beatrice Dal, Buonamici, Lodovico, Lazari, Jonathan, Ioannou, Adam, Porcari, Aldostefano, Patel, Rishi, Razvi, Yousuf, Brown, James, Knight, Daniel, Martinez‐Naharro, Ana, Whelan, Carol, Quarta, Candida C., Manisty, Charlotte, Moon, James, Rowczenio, Dorota, Gilbertson, Janet A., Lachmann, Helen, Wechelakar, Ashutosh, Petrie, Aviva, Moody, William E., Steeds, Richard P., Potena, Luciano, Riefolo, Mattia, Leone, Ornella, Rapezzi, Claudio, Hawkins, Philip N., Gillmore, Julian D., Fontana, Marianna
Publicado 2022

Evaluation of T cell responses to naturally processed variant SARS-CoV-2 spike antigens in individuals following infection or vaccination

por Yin, Zixi, Chen, Ji-Li, Lu, Yongxu, Wang, Beibei, Godfrey, Leila, Mentzer, Alexander J., Yao, Xuan, Liu, Guihai, Wellington, Dannielle, Zhao, Yiqi, Wing, Peter A.C., Dejnirattisa, Wanwisa, Supasa, Piyada, Liu, Chang, Hublitz, Philip, Beveridge, Ryan, Waugh, Craig, Clark, Sally-Ann, Clark, Kevin, Sopp, Paul, Rostron, Timothy, Mongkolsapaya, Juthathip, Screaton, Gavin R., Ogg, Graham, Ewer, Katie, Pollard, Andrew J., Gilbert, Sarah, Knight, Julian C., Lambe, Teresa, Smith, Geoffrey L., Dong, Tao, Peng, Yanchun
Publicado 2023

Medical misinformation: vet the message!

por Hill, Joseph A, Agewall, Stefan, Baranchuk, Adrian, Booz, George W, Borer, Jeffrey S, Camici, Paolo G, Chen, Peng-Sheng, Dominiczak, Anna F, Erol, Çetin, Grines, Cindy L, Gropler, Robert, Guzik, Tomasz J, Heinemann, Markus K, Iskandrian, Ami E, Knight, Bradley P, London, Barry, Lüscher, Thomas F, Metra, Marco, Musunuru, Kiran, Nallamothu, Brahmajee K, Natale, Andrea, Saksena, Sanjeev, Picard, Michael H, Rao, Sunil V, Remme, Willem J, Rosenson, Robert S, Sweitzer, Nancy K, Timmis, Adam, Vrints, Christiaan
Publicado 2019

Evaluation of pediatric epigenetic clocks across multiple tissues

por Fang, Fang, Zhou, Linran, Perng, Wei, Marsit, Carmen J., Knight, Anna K., Cardenas, Andres, Aung, Max T., Hivert, Marie-France, Aris, Izzuddin M., Goodrich, Jaclyn M., Smith, Alicia K., Gaylord, Abigail, Fry, Rebecca C., Oken, Emily, O’Connor, George, Ruden, Douglas M., Trasande, Leonardo, Herbstman, Julie B., Camargo, Carlos A., Bush, Nicole R., Dunlop, Anne L., Dabelea, Dana M., Karagas, Margaret R., Breton, Carrie V., Ober, Carole, Everson, Todd M., Page, Grier P., Ladd-Acosta, Christine
Publicado 2023

Recessive Mutations in SPTBN2 Implicate β-III Spectrin in Both Cognitive and Motor Development

por Lise, Stefano, Clarkson, Yvonne, Perkins, Emma, Kwasniewska, Alexandra, Sadighi Akha, Elham, Parolin Schnekenberg, Ricardo, Suminaite, Daumante, Hope, Jilly, Baker, Ian, Gregory, Lorna, Green, Angie, Allan, Chris, Lamble, Sarah, Jayawant, Sandeep, Quaghebeur, Gerardine, Cader, M. Zameel, Hughes, Sarah, Armstrong, Richard J. E., Kanapin, Alexander, Rimmer, Andrew, Lunter, Gerton, Mathieson, Iain, Cazier, Jean-Baptiste, Buck, David, Taylor, Jenny C., Bentley, David, McVean, Gilean, Donnelly, Peter, Knight, Samantha J. L., Jackson, Mandy, Ragoussis, Jiannis, Németh, Andrea H.
Publicado 2012

Experiences with a researcher-centric ELN

por Badiola, Katrina A., Bird, Colin, Brocklesby, William S., Casson, John, Chapman, Richard T., Coles, Simon J., Cronshaw, James R., Fisher, Adam, Frey, Jeremy G., Gloria, Danmar, Grossel, Martin C., Hibbert, D. Brynn, Knight, Nicola, Mapp, Lucy K., Marazzi, Luke, Matthews, Brian, Milsted, Andy, Minns, Russell S., Mueller, Karl T., Murphy, Kelly, Parkinson, Tim, Quinnell, Rosanne, Robinson, John S., Robertson, Murray N., Robins, Michael, Springate, Emma, Tizzard, Graham, Todd, Matthew H., Williamson, Alice E., Willoughby, Cerys, Yang, Erica, Ylioja, Paul M.
Publicado 2015

Medical Misinformation: Vet the Message!

por Hill, Joseph A, Agewall, Stefan, Baranchuk, Adrian, Booz, George W, Borer, Jeffrey S, Camici, Paolo G, Chen, Peng-Sheng, Dominiczak, Anna F, Erol, Çetin, Grines, Cindy L, Gropler, Robert, Guzik, Tomasz J, Heinemann, Markus K, Iskandrian, Ami E, Knight, Bradley P, London, Barry, Lüscher, Thomas F, Metra, Marco, Musunuru, Kiran, Nallamothu, Brahmajee K, Natale, Andrea, Saksena, Sanjeev, Picard, Michael H, Rao, Sunil V, Remme, Willem J, Rosenson, Robert S, Sweitzer, Nancy K, Timmis, Adam, Vrints, Christiaan
Publicado 2019

Advanced glycation end products are elevated in estrogen receptor-positive breast cancer patients, alter response to therapy, and can be targeted by lifestyle intervention

por Walter, Katherine R., Ford, Marvella E., Gregoski, Mathew J., Kramer, Rita M., Knight, Kendrea D., Spruill, Laura, Nogueira, Lourdes M., Krisanits, Bradley A., Phan, Van, La Rue, Amanda C., Lilly, Michael B., Ambs, Stefan, Chan, King, Turner, Tonya F., Varner, Heidi, Singh, Shweta, Uribarri, Jaime, Garrett-Mayer, Elizabeth, Armeson, Kent E., Hilton, Ebony J., Clair, Mark J., Taylor, Marian H., Abbott, Andrea M., Findlay, Victoria J., Peterson, Lindsay L., Magwood, Gayenell, Turner, David P.
Publicado 2018