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401por von Falkenhausen, Aenne S., Freudling, Rebecca, Waldenberger, Melanie, Gieger, Christian, Peters, Annette, Müller-Nurasyid, Martina, Kääb, Stefan, Sinner, Moritz F.“…Methods and Results: We studied the large, community-based KORA F4 Study. Of 3,080 participants enrolled between 2006 and 2007 with detailed information on demographic, anthropometric, clinical, and ECG characteristics, 2,575 presented with available data on leukocyte telomere length. …”
Publicado 2022
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402por Li, Xiangwei, Delerue, Thomas, Schöttker, Ben, Holleczek, Bernd, Grill, Eva, Peters, Annette, Waldenberger, Melanie, Thorand, Barbara, Brenner, Hermann“…These associations are confirmed in another independent population-based cohort study, the KORA-Age study, conducted in older adults. In conclusion, we identify 65 CpGs as frailty-related loci, of which 20 CpGs are used to calculate the eFRS with predictive performance for frailty over long-term follow-up.…”
Publicado 2022
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403por Kulka, Charlotte, Lorbeer, Roberto, Askani, Esther, Kellner, Elias, Reisert, Marco, von Krüchten, Ricarda, Rospleszcz, Susanne, Hasic, Dunja, Peters, Annette, Bamberg, Fabian, Schlett, Christopher L.“…Methods: 3-Tesla MRIs were performed on 400 subjects enrolled in the KORA (Cooperative Health Research in the Augsburg Region) MRI study. …”
Publicado 2022
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404por Dong, Qiuling, Sidra, Sidra, Gieger, Christian, Wang-Sattler, Rui, Rathmann, Wolfgang, Prehn, Cornelia, Adamski, Jerzy, Koenig, Wolfgang, Peters, Annette, Grallert, Harald, Sharma, Sapna“…Here, we used 146 targeted metabolomic profiles from the German KORA FF4 cohort consisting of 1715 participants and associated them with obesity and type 2 diabetes. …”
Publicado 2023
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405por Liu, Congcong, Goh, Shin Giek, You, Luhua, Yuan, Qiyi, Mohapatra, Sanjeeb, Gin, Karina Yew-Hoong, Chen, Baoliang“…Furthermore, transcriptional expression levels of genes encode for mating pairing formation (trbB), DNA replication and translocation (trfA), and global regulators (korA, korB, trbA) are regulated by QACs. And we demonstrate for the first time that QACs decreased the concentration of extracellular AI-2 signals, which was verified to be involved in regulating conjugative transfer genes (trbB, trfA). …”
Publicado 2023
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406por Kolz, Melanie, Baumert, Jens, Müller, Martina, Khuseyinova, Natalie, Klopp, Norman, Thorand, Barbara, Meisinger, Christine, Herder, Christian, Koenig, Wolfgang, Illig, Thomas“…METHODS: A case-cohort study was conducted in initially healthy, middle-aged subjects from the MONICA/KORA Augsburg studies including 498 individuals with incident type 2 diabetes and 1,569 non-cases. …”
Publicado 2008
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407por Meisinger, Christa, Heier, Margit, Landgraf, Rüdiger, Happich, Michael, Wichmann, H-Erich, Piehlmeier, Wolfgang“…METHODS: The presented data were derived from the 'KORA Augsburg Diabetes Family Study', conducted between October 2001 and September 2002. …”
Publicado 2008
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408por Vogel, Carla IG, Greene, Brandon, Scherag, André, Müller, Timo D, Friedel, Susann, Grallert, Harald, Heid, Iris M, Illig, Thomas, Wichmann, H-Erich, Schäfer, Helmut, Hebebrand, Johannes, Hinney, Anke“…The adult GWA included 1,644 individuals from a German population-based study (KORA). The 775 independent German families consisted of extremely obese children and adolescents and their parents. …”
Publicado 2009
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409por Tan, Susanne, Scherag, André, Janssen, Onno Eilard, Hahn, Susanne, Lahner, Harald, Dietz, Tiina, Scherag, Susann, Grallert, Harald, Vogel, Carla Ivane Ganz, Kimmig, Rainer, Illig, Thomas, Mann, Klaus, Hebebrand, Johannes, Hinney, Anke“…To compare the effect of FTO obesity risk alleles on BMI in patients with PCOS to unselected females of the same age range we genotyped 1,971 females from the population-based KORA-S4 study (Kooperative Gesundheitsforschung im Raum Augsburg, Survey 4). …”
Publicado 2010
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410por Schnabel, Eva, Chen, Chih-Mei, Koch, Beate, Karrasch, Stefan, Jörres, Rudolf A, Schäfer, Torsten, Vogelmeier, Claus, Ewert, Ralf, Schäper, Christoph, Völzke, Henry, Obst, Anne, Felix, Stephan B, Wichmann, H-Erich, Gläser, Sven, Heinrich, Joachim“…METHODS: Within three studies (KORA C, SHIP-I, ECRHS-I) in different areas of Germany 4059 adults performed lung function tests. …”
Publicado 2010
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411por Suhre, Karsten, Meisinger, Christa, Döring, Angela, Altmaier, Elisabeth, Belcredi, Petra, Gieger, Christian, Chang, David, Milburn, Michael V., Gall, Walter E., Weinberger, Klaus M., Mewes, Hans-Werner, Hrabé de Angelis, Martin, Wichmann, H.-Erich, Kronenberg, Florian, Adamski, Jerzy, Illig, Thomas“…METHODOLOGY/PRINCIPAL FINDINGS: 40 individuals with self-reported diabetes and 60 controls (male, over 54 years) were randomly selected from the participants of the population-based KORA (Cooperative Health Research in the Region of Augsburg) study, representing an extensively phenotyped sample of the general German population. …”
Publicado 2010
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412por Mittelstrass, Kirstin, Ried, Janina S., Yu, Zhonghao, Krumsiek, Jan, Gieger, Christian, Prehn, Cornelia, Roemisch-Margl, Werner, Polonikov, Alexey, Peters, Annette, Theis, Fabian J., Meitinger, Thomas, Kronenberg, Florian, Weidinger, Stephan, Wichmann, Heinz Erich, Suhre, Karsten, Wang-Sattler, Rui, Adamski, Jerzy, Illig, Thomas“…For discovery and replication we used more than 3,300 independent individuals from KORA F3 and F4 with metabolite measurements of 131 metabolites, including amino acids, phosphatidylcholines, sphingomyelins, acylcarnitines, and C6-sugars. …”
Publicado 2011
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413por Yu, Zhonghao, Zhai, Guangju, Singmann, Paula, He, Ying, Xu, Tao, Prehn, Cornelia, Römisch-Margl, Werner, Lattka, Eva, Gieger, Christian, Soranzo, Nicole, Heinrich, Joachim, Standl, Marie, Thiering, Elisabeth, Mittelstraß, Kirstin, Wichmann, Heinz-Erich, Peters, Annette, Suhre, Karsten, Li, Yixue, Adamski, Jerzy, Spector, Tim D, Illig, Thomas, Wang-Sattler, Rui“…We report results from two population-based studies: the KORA F4 study from Germany as a discovery cohort, with 1038 female and 1124 male participants (32–81 years), and the TwinsUK study as replication, with 724 female participants. …”
Publicado 2012
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414por Floegel, Anna, Stefan, Norbert, Yu, Zhonghao, Mühlenbruch, Kristin, Drogan, Dagmar, Joost, Hans-Georg, Fritsche, Andreas, Häring, Hans-Ulrich, Hrabě de Angelis, Martin, Peters, Annette, Roden, Michael, Prehn, Cornelia, Wang-Sattler, Rui, Illig, Thomas, Schulze, Matthias B., Adamski, Jerzy, Boeing, Heiner, Pischon, Tobias“…They were further linked to insulin sensitivity and secretion in the Tübingen Family study and were partly replicated in the independent KORA (Cooperative Health Research in the Region of Augsburg) cohort. …”
Publicado 2013
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415por Ruf, Esther, Baumert, Jens, Meisinger, Christa, Döring, Angela, Ladwig, Karl-Heinz“…METHODS: Three cross-sectional MONICA surveys (conducted 1984–1995) including 11,282 subjects aged 25–74 years were followed up within the framework of KORA (Cooperative Health Research in the Region of Augsburg), a population-based cohort, until 2002. …”
Publicado 2014
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416por Jourdan, Carolin, Linseisen, Jakob, Meisinger, Christa, Petersen, Ann-Kristin, Gieger, Christian, Rawal, Rajesh, Illig, Thomas, Heier, Margit, Peters, Annette, Wallaschofski, Henri, Nauck, Matthias, Kastenmüller, Gabi, Suhre, Karsten, Prehn, Cornelia, Adamski, Jerzy, Koenig, Wolfgang, Roden, Michael, Wichmann, H-Erich, Völzke, Henry“…The aim was to characterise associations between circulating thyroid hormones—free thyroxine (FT4) and thyrotropin (TSH)—and the metabolite profiles in serum samples from participants of the German population-based KORA F4 study. Analyses were based on the metabolite profile of 1463 euthyroid subjects. …”
Publicado 2013
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417por Voss, Andreas, Schroeder, Rico, Heitmann, Andreas, Peters, Annette, Perz, Siegfried“…In a previous study, we could show significant variations of 5-min HRV indices according to age in almost all domains (linear and nonlinear) in 1906 healthy subjects from the KORA S4 cohort. Based on the same group of subjects, general gender-related influences on HRV indices are to be determined in this study. …”
Publicado 2015
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418por Nagirnaja, Liina, Nõmmemees, Diana, Rull, Kristiina, Christiansen, Ole B., Nielsen, Henriette S., Laan, Maris“…Comparative prevalence of the studied ANXA5 genetic variants in human populations was estimated based on the 1000 Genomes Project (n = 675, whole-genome sequencing data) and the KORA S3 500K dataset of South German samples (n = 1644, genome-wide genotyping data). …”
Publicado 2015
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419por Krumsiek, Jan, Mittelstrass, Kirstin, Do, Kieu Trinh, Stückler, Ferdinand, Ried, Janina, Adamski, Jerzy, Peters, Annette, Illig, Thomas, Kronenberg, Florian, Friedrich, Nele, Nauck, Matthias, Pietzner, Maik, Mook-Kanamori, Dennis O., Suhre, Karsten, Gieger, Christian, Grallert, Harald, Theis, Fabian J., Kastenmüller, Gabi“…In the present study, we conducted a large-scale metabolomics analysis of 507 metabolic markers measured in serum of 1756 participants from the German KORA F4 study (903 females and 853 males). One-third of the metabolites show significant differences between males and females. …”
Publicado 2015
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420por Burri, Andrea, Marinova, Zoya, Robinson, Mark D., Kühnel, Brigitte, Waldenberger, Melanie, Wahl, Simone, Kunze, Sonja, Gieger, Christian, Livshits, Gregory, Williams, Frances“…The replication sample included 729 men and 756 women from a subsample of the KORA S4 survey–an independent population-based cohort from Southern Germany. …”
Publicado 2016
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