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2561por Rice, D C“…Enormous effort has been focused over the last decade and a half on characterizing the behavioral effects of lead in the developing organism. While age-appropriate standardized measures of intelligence (IQ) have been the dependent variable most often used to assess lead-induced cognitive impairment in epidemiologic studies, researchers have also used a variety of other methods designed to assess specific behavioral processes sensitive to lead. …”
Publicado 1996
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2562por Harlan, W R“…Numerous observations have indicated a relationship between moderate or heavy lead exposure and high blood pressure. To determine whether low-level lead exposure is related to blood pressure in the U.S. population, we analyzed data from the National Health and Nutrition Examination Survey II for persons 12 to 74 years of age. …”
Publicado 1988
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2563“…Studies performed earlier have shown a positive relation between blood lead (a parameter for lead body burden) and blood pressure, whereas such a relation between urine cadmium (a parameter for cadmium body burden) and blood pressure could not be shown. …”
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2564
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2565“…These results indicate that rats exposed to low levels of lead from conception until adulthood show a delay in nervous system development. …”
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2566por David, Oliver J.“…Hyperactive children were compared with a nonhyperactive control group on two measures that reflect the presence of body lead and on a lead exposure questionnaire. The overall hypothesis that was tested was that a relationship exists between hyperactivity in children and a concommitant condition of increased body lead stores. …”
Publicado 1974
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2567“…Reports of neurologic impairment of children following recovery from acute lead encephalopathy have raised questions concerning the effects of chronic low-level lead exposure on the central nervous system. …”
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2568por Sachs, Henrietta K.“…A biphase program of screening and treating high-risk children for lead poisoning resulted in a 30% fall in mean lead values in the target areas over a 5-year period. …”
Publicado 1974
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2569“…The infant baboon, established as a metabolic model for a child ingesting lead, will be used to determine the adequacy of present as well as recently recommended limitations for lead in paint to assure protection from this potential source of lead exposure. …”
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2570“…In the study of human populations, much emphasis is placed on the concentration of lead in whole peripheral blood. There is a considerable body of evidence which indicates that this measurement reflects recent and current assimilation of lead. …”
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2571“…When infant rhesus monkeys were exposed to lead via the addition of lead acetate (0.5–9 mg/kg body weight) to their formula or by the consumption of lead particles from lead-based surrogate mothers, they developed symptoms of lead intoxication within 6 weeks. …”
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2572“…Dynamics of lead metabolism were studied by replacement of a portion of the dietary lead with stable isotope tracers, and maintaining subjects on controlled diets for about 6 months. …”
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2573“…Lead encephalopathy was induced in developing Long-Evans rats by adding lead carbonate (4% w/w) to the diet of nursing mother immediately after delivery. …”
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2574“…K-X-ray fluorescence (K-XRF) is a useful tool for assessing environmental exposure to lead in occupationally exposed individuals and older adults. …”
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2575“…In vivo X-ray fluorescence (XRF) measurement of bone lead concentration (XRF) has emerged as an important technique for future epidemiological studies of long-term toxicity. …”
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2576por Landrigan, P J“…Lead exposure is widespread among industrial populations in the United States. …”
Publicado 1991
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2577por O'Flaherty, E J“…A physiologically based model of lead kinetics in children and adults has been developed and tested. …”
Publicado 1998
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2578“…Dietary calcium is well known to decrease gastrointestinal lead absorption and thereby reduce the risk for lead poisoning. …”
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2579por Goyer, R A“…Although the toxicity of lead was recognized centuries ago, concern was restricted to overt symptoms: colic, encephalopathy, anemia, or renal disease. …”
Publicado 1990
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2580“…Monkeys were pre- and postnatally exposed to lead via the diet. Blood lead levels at the time of testing were 9.3, 40.3, and 55.7 micrograms/dL in controls, and animals exposed to 350 ppm or 600 ppm lead acetate, respectively. …”
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