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  1. 486961
    “…BACKGROUND: Ovarian cancer is the third leading site of cancer among women, trailing behind cervix and breast cancer. …”
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    Epithelial ovarian tumors: Clinicopathological correlation and immunohistochemical study
  2. 486962
    “…CONCLUSIONS: These results suggest that feeding high concentrate diet to lactating goats for 10 wk leads to the activation of the inflammatory response, and decreases the anti-oxidant capacity, and subsequently impairs the mitochondrial function in the liver. …”
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    Comparative proteomic analysis of the effects of high-concentrate diet on the hepatic metabolism and inflammatory response in lactating dairy goats
  3. 486963
    “…BACKGROUND: Molecular mechanisms leading to the adaptation of breast cancer (BC) cells to hypoxia are largely unknown. …”
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    Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications
  4. 486964
    “…In Ethiopia, vitamin A deficiency leads to 80,000 deaths a year and affects 61 % of preschool children. …”
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    Prevalence and associated factors of clinical manifestations of vitamin a deficiency among preschool children in asgede-tsimbla rural district, north Ethiopia, a community based cross sectional study
  5. 486965
    “…The most influential factor leading to understanding of CC and its impact on health was education. …”
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    Knowledge and perception about climate change and human health: findings from a baseline survey among vulnerable communities in Bangladesh
  6. 486966
    “…Indoor radon is the second leading risk factor of lung cancer after cigarette smoking among ever smokers and the first among non-smokers. …”
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    Residential radon and environmental burden of disease among Non-smokers
  7. 486967
    “…The main challenges facing cell therapies relate to (1) the identification of the most appropriate path to reimbursement, and (2) price setting, whereas high manufacturing costs of these therapies will dictate a high price that could only be achieved by a product that leads to important additional patient benefits compared to available treatment options. …”
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    Market access pathways for cell therapies in France
  8. 486968
    “…We suspect the existence of a feed-forward signal from leptin in second half of pregnancy, stimulating a positive energy balance and leading to greater weight gain. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12884-016-0842-y) contains supplementary material, which is available to authorized users.…”
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    Higher maternal leptin levels at second trimester are associated with subsequent greater gestational weight gain in late pregnancy
  9. 486969
    “…The HMGB1-DNA complex binds to RAGE on neighboring cells and then CpG DNA is recognized by TLR9 in lysosomes, leading to generation of nitric oxide and 8-nitroG formation. …”
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    Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation
  10. 486970
    “…OBJECTIVES: Autophagy-related 16-like 1 (ATG16L1) deficiency leads to impaired cellular autophagy and bacterial degradation as well as an altered cytokine production. …”
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    Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease
  11. 486971
    “…However, compared with 1D11, which neutralized secreted TGF-β1 but did not affect intracellular TGF-β1 levels, naringenin reduced the secretion of TGF-β1 from the cells, leading to an accumulation of intracellular TGF-β1. …”
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    Naringenin prevents TGF-β1 secretion from breast cancer and suppresses pulmonary metastasis by inhibiting PKC activation
  12. 486972
    “…Which contribute to the cultivated populations leading to heterogeneity in its genetic pool and consequently affects the production consistency of M. cephalus in Egypt.…”
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    Genetic structure of Mugil cephalus L. populations from the northern coast of Egypt
  13. 486973
    “…BACKGROUND: Cervical cancer (CC) is a leading cause of mortality in females, especially in developing countries. …”
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    Serine/threonine kinases 31(STK31) may be a novel cellular target gene for the HPV16 oncogene E7 with potential as a DNA hypomethylation biomarker in cervical cancer
  14. 486974
    “…Web-based participation was more likely for those who completed higher levels of education; each interval increase leading to a 1.83 increase in the odds of website platform usage (P<.001). …”
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    Assessing the Effects of Participant Preference and Demographics in the Usage of Web-based Survey Questionnaires by Women Attending Screening Mammography in British Columbia
  15. 486975
    “…BACKGROUND: Leprosy is a chronic infectious disease of public health importance and one of the leading causes of permanent physical disability. Nevertheless, the drop in prevalence following multidrug therapy has resulted in the neglect of leprosy. …”
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    Performance of general health workers in leprosy control activities at public health facilities in Amhara and Oromia States, Ethiopia
  16. 486976
    “…CONCLUSIONS: Our results suggest that overproduction of hepcidin by IL-6 signaling might be a major factor that leads to functionally iron-deficient cancer-related anemia in the LC-06-JCK model. …”
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    Treatment with anti-IL-6 receptor antibody prevented increase in serum hepcidin levels and improved anemia in mice inoculated with IL-6–producing lung carcinoma cells
  17. 486977
    “…Under this scenario, climatic fluctuations throughout the Pleistocene would have altered the distribution of suitable habitat for mistletoes throughout Mesoamerica leading to variation in population continuity and isolation. …”
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    A mistletoe tale: postglacial invasion of Psittacanthus schiedeanus (Loranthaceae) to Mesoamerican cloud forests revealed by molecular data and species distribution modeling
  18. 486978
    “…ChIP analyses revealed that 6-MP dampened LPS-induced histone H3 acetylation of chromatin surrounding the TNF-α promoter, ultimately leading to a decrease in p65/coactivator-mediated transcription of TNF-α gene. …”
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    6-Mercaptopurine attenuates tumor necrosis factor-α production in microglia through Nur77-mediated transrepression and PI3K/Akt/mTOR signaling-mediated translational regulation
  19. 486979
    “…However, the safety of deep-fried edible oil, which is ingested with fried food, is a concern, because the oil is exposed continuously to be re-used at a high temperature, leading to a number of well-known chemical reactions. …”
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    Deep-fried oil consumption in rats impairs glycerolipid metabolism, gut histology and microbiota structure
  20. 486980
    por Patra, Shraboni
    Publicado 2016
    “…Pregnancy and childbirth complications are among the leading causes of death in girls aged 15 to 19 years. …”
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    Motherhood in childhood: addressing reproductive health hazards among adolescent married women in India
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