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  1. 487301
    “…Dengue incidences have perpetually increased, leading to an annual (uncertain) peak. Dengue cases cause an enormous public health problem in Thailand because there is no anti-viral drug against the dengue virus. …”
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    The association between dengue incidences and provincial-level weather variables in Thailand from 2001 to 2014
  2. 487302
    por Waheed, Abdul, Cason, Frederick D
    Publicado 2019
    “…Introduction Rectal cancer remains a leading cause of cancer morbidity and mortality in the United States. …”
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    Adjuvant Radiation Survival Benefits in Patients with Stage 1B Rectal Cancer: A Population-based Study from the Surveillance Epidemiology and End Result Database (1973–2010)
  3. 487303
    “…Glutamate then activates perisynaptic mGlu(5)Rs to initiate the endocannabinoid retrograde inhibition of GABAergic transmission in the vlPAG, leading to analgesia.…”
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    Neuropeptide S-initiated sequential cascade mediated by OX(1), NK(1), mGlu(5) and CB(1) receptors: a pivotal role in stress-induced analgesia
  4. 487304
    “…BACKGROUND: Ambient fine particulate matter pollution (PM(2.5)) is one leading cause of disease burden, but no study has quantified the association between daily PM(2.5) exposure and life expectancy. …”
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    Potential gains in life expectancy by attaining daily ambient fine particulate matter pollution standards in mainland China: A modeling study based on nationwide data
  5. 487305
    “…Additionally, this strategy leads to small jumps in k-space thereby minimizing eddy current related artifacts. …”
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    Highly accelerated 4D flow cardiovascular magnetic resonance using a pseudo-spiral Cartesian acquisition and compressed sensing reconstruction for carotid flow and wall shear stress
  6. 487306
    “…CONCLUSIONS: On the whole, these results suggest that i) the intake of the BCAA-based commercially available supplement used in this study reduces RPE as a likely consequence of an improvement in the serum tryptophan: BCAA ratio; ii) over time, reduced RPE allows subjects to sustain higher workloads, leading to increased TRIMP and TTE.…”
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    Effects of a commercially available branched-chain amino acid-alanine-carbohydrate-based sports supplement on perceived exertion and performance in high intensity endurance cycling tests
  7. 487307
    por Cui, Yubao, Hong, Shanchao, Zhu, Xuming
    Publicado 2020
    “…BACKGROUND: Ovarian cancer is the 5th leading cause of death of women due to cancer in the United States. …”
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    The Accuracy of Single MicroRNAs in Peripheral Blood to Diagnose Ovarian Cancer: An Updated Meta-Analysis
  8. 487308
    “…Dysregulated miR-221-3p expression, as seen in synovium of RA patients, leads to a diminished anti-inflammatory response and drives M2-macrophages to exhibit a M1-cytokine profile.…”
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    miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation
  9. 487309
    “…The United States has occupied the leading position since the inception of the field, with the largest number of articles published. …”
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    Systematic Evaluation of Research Progress on Natural Language Processing in Medicine Over the Past 20 Years: Bibliometric Study on PubMed
  10. 487310
    “…Cervical cancer was the leading cause of cancer-related death in women in eastern, western, middle, and southern Africa. …”
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    Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis
  11. 487311
    “…Over-production of PAR polymers prompts the release of AIF from the mitochondria and translocation to the nucleus, which leads to parthanatos. Activated mTOR may interact with PARP-1 via SIRT1 to regulate visible light-induced parthanatos. …”
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    mTOR may interact with PARP-1 to regulate visible light-induced parthanatos in photoreceptors
  12. 487312
    “…BACKGROUND: Osteoarthritis is one of the leading causes of pain and disability worldwide, and a large percentage of patients with osteoarthritis are individuals who are also obese. …”
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    Impact of age on host responses to diet-induced obesity: Development of joint damage and metabolic set points
  13. 487313
    “…MBR-related parameters of the ONH such as MBR of all area (MA), MBR of vascular area (MV), and MBR of tissue area (MT) decreased significantly at 2 weeks after IVR compared to baseline values (MA, CONCLUSION: IVR injection leads to a reduction of ocular blood flow both in the ONH and in the retinal peripapillary vessels associated with peripapillary vessel constriction. …”
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    Changes in Ocular Blood Flow after Ranibizumab Intravitreal Injection for Diabetic Macular Edema Measured Using Laser Speckle Flowgraphy
  14. 487314
    “…Dapagliflozin treatment also significantly reduced Y792 tyrosine phosphorylation of DDR1 leading to decrement of DDR1 function and detachment of cancer cells. …”
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    Dapagliflozin Inhibits Cell Adhesion to Collagen I and IV and Increases Ectodomain Proteolytic Cleavage of DDR1 by Increasing ADAM10 Activity
  15. 487315
    “…Twenty-one patients (26.6%) developed a drug-related adverse event, leading to rifampin interruption in 6 of them (7.6% of total cohort). …”
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    Duration of rifampin therapy is a key determinant of improved outcomes in early-onset acute prosthetic joint infection due to Staphylococcus treated with a debridement, antibiotics and implant retention (DAIR): a retrospective multicenter study in France
  16. 487316
    “…INTRODUCTION: The Cryptococcus neoformans/gattii species complexes are a leading cause of fatality among HIV-infected patients. …”
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    Cryptococcus neoformans/gattii Species Complexes from Pre-HIV Pandemic Era Contain Unusually High Rate of Non-Wild-Type Isolates for Amphotericin B
  17. 487317
    “…It was hypothesized that, as a consequence of the pulsatile push-pull flow through the dialyser, the boundary layers at the membrane surface would be disrupted, thereby enhancing solute transport across the membrane, modifying protein fouling and maintaining the surface area available for mass and fluid transport throughout the whole treatment, leading to solute transport (clearance) enhancement compared to normal haemodialysis (HD) operation. …”
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    Enhancement of solute clearance using pulsatile push-pull dialysate flow for the Quanta SC+: A novel clinic-to-home haemodialysis system
  18. 487318
    “…Both peptides displayed bactericidal activity and caused a loss of the bacterial envelope integrity leading to a rapid drop in cell viability. Regarding amoebae and THP-1-derived macrophages, SHa was less toxic than [K(3)]SHa and exhibited low half maximal lethal concentrations (LC(50)). …”
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    In vitro and intracellular activities of frog skin temporins against Legionella pneumophila and its eukaryotic hosts
  19. 487319
    por Li, Zhe, Lyu, Cong, Ren, Yun, Wang, Hailin
    Publicado 2020
    “…Instead of a direct interaction between TET2 and [Formula: see text] , data of our Co-IP, BSP, and ChIP-qPCR experiments indicated that the activated [Formula: see text] increased the DNA methyltransferase (DNMT)-mediated promoter methylation of TET2, leading to an inhibition of the TET2 expression and DNA hydroxymethylation. …”
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    Role of TET Dioxygenases and DNA Hydroxymethylation in Bisphenols-Stimulated Proliferation of Breast Cancer Cells
  20. 487320
    “…Cutoff was 0·35 for sensitivity of 0·90 or greater and 0·67 for specificity of 0·90 or greater in the derivation cohort, leading to a positive predictive value (PPV) of 0·83 (84/101) and a negative predictive value (NPV) of 0·85 (93/110). …”
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    FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steatohepatitis with significant activity and fibrosis: a prospective derivation and global validation study
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