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487401“…Among fatal injuries, traffic accidents 38/73 (52%) and violence 18/73 (25%) were the leading causes of death. Mass gathering injuries were more likely to occur among individuals aged 21-40 years (odds ratio [OR] 3.5; 95% CI 2.7-4.5) and >41 years (OR 7.6; 95% CI 5.4-10.6) versus those <21 years; more likely to be unintentional than assault (OR 5.3; 95% CI 1.8-15.5); more likely to happen on the street versus at home (OR 37.7; 95% CI 22.4-63.6); less likely to happen at night than during the day (OR 0.2; 95% CI 0.1-0.4); and less likely to result in hospital admission (OR 0.5; 95% CI 0.3-0.7). …”
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487402por Tham, Yih-Chung, Liu, Lei, Rim, Tyler Hyungtaek, Zhang, Liang, Majithia, Shivani, Chee, Miao Li, Tan, Nicholas Y. Q., Wong, Kah-Hie, Ting, Daniel Shu Wei, Sabanayagam, Charumathi, Wang, Jie Jin, Mitchell, Paul, Wong, Tien Yin, Cheng, Ching-Yu“…IMPORTANCE: Cataracts and diabetic retinopathy (DR) are the leading causes of acquired blindness worldwide. Although extraction is the standard treatment option for cataracts, it is also reported to increase the risk of developing DR among individuals with diabetes. …”
Publicado 2020
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487403por Cziraky, Mark J., Abbott, Scott, Nguyen, Matt, Larholt, Kay, Apgar, Elizabeth, Wasser, Thomas, Strange, Poul, Shi, Leon, Harrison, H. Courtenay, Everitt, Beverly, Nowak, Lynn“…Background: Many patients with type 2 diabetes mellitus (T2DM) do not have adequate glycemic control, leading to poor patient outcomes and high healthcare costs. …”
Publicado 2019
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487404por Pels, Anouk, Derks, Jan, Elvan-Taspinar, Ayten, van Drongelen, Joris, de Boer, Marjon, Duvekot, Hans, van Laar, Judith, van Eyck, Jim, Al-Nasiry, Salwan, Sueters, Marieke, Post, Marinka, Onland, Wes, van Wassenaer-Leemhuis, Aleid, Naaktgeboren, Christiana, Jakobsen, Janus C., Gluud, Christian, Duijnhoven, Ruben G., Lely, Titia, Gordijn, Sanne, Ganzevoort, Wessel“…IMPORTANCE: Severe early onset fetal growth restriction caused by placental dysfunction leads to high rates of perinatal mortality and neonatal morbidity. …”
Publicado 2020
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487405“…In total, 102 users reached out to a health care provider, leading to 91 contacts. CONCLUSIONS: Our study demonstrated the successful implementation and use of an app with COVID-19 education, self-assessment, and a 7-day symptom diary. …”
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487406“…Further, Salmonella spp. are a significant cause of avian mortality, leading to additional conservation concerns. Despite numerous studies of enteric bacteria in wild birds and policies to discourage birds from food systems, we lack a comprehensive understanding of wild bird involvement in transmission of enteric bacteria to humans. …”
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487407por Xie, Chen, Zhang, Li‐Zhen, Chen, Zhan‐Li, Zhong, Wang‐Jing, Fang, Jian‐Hong, Zhu, Ying, Xiao, Man‐Huan, Guo, Zhi‐Wei, Zhao, Na, He, Xionglei, Zhuang, Shi‐Mei“…Mechanistically, miR‐125a/b and miR‐124 suppressed the expression of tumor necrosis factor receptor‐associated factor 6 (TRAF6), but PDIA3P1 bound to miR‐125a/b/miR‐124 and relieved their repression on TRAF6, leading to activation of the nuclear factor kappa B (NF‐κB) pathway. …”
Publicado 2019
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487408por Faizal, W.M., Ghazali, N.N.N., Khor, C.Y., Badruddin, Irfan Anjum, Zainon, M.Z., Yazid, Aznijar Ahmad, Ibrahim, Norliza Binti, Razi, Roziana Mohd“…Clinically significant obstruction can develop anywhere throughout the upper airway, leading to asphyxia and death; this is where recognition and treatment are essential and lifesaving. …”
Publicado 2020
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487409por Saeedi Saravi, Seyed Soheil, Eroglu, Emrah, Waldeck-Weiermair, Markus, Sorrentino, Andrea, Steinhorn, Benjamin, Belousov, Vselovod, Michel, Thomas“…We conclude that H(2)O(2) generated in the cell nucleus activates AMPK, leading to eNOS phosphorylation; in contrast, AMPK activation by cytosol- or caveolae-derived H(2)O(2) does not promote eNOS phosphorylation via AMPK. …”
Publicado 2020
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487410por Zhou, Jiebai, Ding, Ning, Xu, Xiaobo, Zhang, Yong, Ye, Maosong, Li, Chun, Hu, Jie“…BACKGROUND: Lung cancer is now the leading cause of cancer mortality worldwide for both men and women. …”
Publicado 2020
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487411por Hosaka, Shinichiro, Yamada, Tetsuya, Takahashi, Kei, Dan, Takashi, Kaneko, Keizo, Kodama, Shinjiro, Asai, Yoichiro, Munakata, Yuichiro, Endo, Akira, Sugawara, Hiroto, Kawana, Yohei, Yamamoto, Junpei, Izumi, Tomohito, Sawada, Shojiro, Imai, Junta, Miyata, Toshio, Katagiri, Hideki“…On the other hand, under HFD feeding conditions, food intake was decreased in PAI-1 KO as compared with WT mice (HFD-WT mice 3.98 ± 0.08 g/day vs HFD-KO mice 3.73 ± 0.07 g/day, P = 0.021), leading to an eventual significant suppression of weight gain (HFD-WT mice 40.3 ± 1.68 g vs HFD-KO mice 34.6 ± 1.84 g, P = 0.039). …”
Publicado 2020
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487412por Martin-Fernandez, Judith, Affret, Aurelie, Martel, Emma, Gallard, Romain, Merchadou, Laurence, Moinot, Laetitia, Termote, Monique, Dejarnac, Vincent, Alla, François, Cambon, Linda“…It will provide knowledge about the strategic configurations most suitable for leading to life skills mobilisation and change young people’s representations about SU. …”
Publicado 2020
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487413por Ma, Tingyu, Gao, Han, Zhang, Dong, Shi, Yuhua, Zhang, Tianyuan, Shen, Xiaofeng, Wu, Lan, Xiang, Li, Chen, Shilin“…RESULTS: In this study, we found that cross-talk between UV-B and GA induced processes leading to modifications in artemisinin accumulation. …”
Publicado 2020
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487414por Si, Xiang, Ma, Jie, Cao, Dai-Yin, Xu, Hai-Lin, Zuo, Ling-Yun, Chen, Min-Ying, Wu, Jian-Feng, Guan, Xiang-Dong“…TEE used in addition to TTE led to a new diagnosis without therapeutic implications (class 2) in 11 patients (16.2%) and made a major clinical contribution leading to a therapeutic change (class 3) in 23 patients (33.8%). …”
Publicado 2020
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487415“…BACKGROUND: Coronary heart disease (CHD) is one of the leading causes of death worldwide. Percutaneous coronary intervention (PCI) has been an important technology for the treatment of CHD. …”
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487416por Abbott, Robert D, Sherwin, Kyle, Klopf, Hannah, Mattingly, Holly J, Brogan, Kelly“…Background Major depressive disorder (MDD) is a complex bio-psycho-social syndrome that affects millions of individuals and is one of the leading causes of impaired quality of life (QOL). …”
Publicado 2020
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487417por Bailey, Jeanette, Opondo, Charles, Lelijveld, Natasha, Marron, Bethany, Onyo, Pamela, Musyoki, Eunice N., Adongo, Susan W., Manary, Mark, Briend, André, Kerac, Marko“…Study limitations included contextual factors leading to defaulting, a combined multi-country power estimate, and operational constraints. …”
Publicado 2020
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487418“…Opioids bind to TLR4, in a manner parallel to LPS, activating TLR4 signaling, which leads to nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) expression and the production of the pro-inflammatory cytokines tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6. …”
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487419por Tesfaye, Brook, K. Makam, Jeevan, Sergon, Kibet, Onuekwusi, Iheoma, Muitherero, Charles, Sowe, Alieu“…AFP surveillance was conducted in all health facilities supervised leading to the detection and investigation of 11 unreported AFP cases. …”
Publicado 2020
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487420por Wanitphakdeedecha, Rungsima, Kantaviro, Watsachon, Suphatsathienkul, Panittra, Tantrapornpong, Ploypailin, Yan, Chadakan, Apinumtham, Chalermkwan, Srinoulprasert, Yuttana“…RESULTS: Significantly higher levels of IgG against complexing protein were detected in onaA-tolerant sera but not in onaA-responders, leading to proposals that anti-complexing protein antibodies could cause onaA unresponsiveness. …”
Publicado 2020
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