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  1. 487441
    “…BACKGROUND: Hepatocellular carcinoma (HCC) is the third leading cause of cancer death, causing about 750000 deaths worldwide every year. …”
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    Value of miR-1271 and glypican-3 in evaluating the prognosis of patients with hepatocellular carcinoma after transcatheter arterial chemoembolization
  2. 487442
    “…These data show for the first time a miR-mediated control of the peptide transporter subunit TAP1 in melanoma thereby leading to a reduced HLA-I surface expression accompanied by an altered immune recognition and reduced patients’ survival. …”
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    Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients
  3. 487443
    “…We repeated this analysis using genetic variants independent of the leading association at core HDL pathway genes and found that these variants were also associated with risk for BCs (OR = 1.11, 95% CI = 1.06–1.16, P = 1.5 × 10(−6)), including locus-specific associations at ABCA1 (ATP Binding Cassette Subfamily A Member 1), APOE-APOC1-APOC4-APOC2 (Apolipoproteins E, C1, C4, and C2), and CETP (Cholesteryl Ester Transfer Protein). …”
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    The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study
  4. 487444
    “…Infective or inflammatory agents cause neutrophil recruitment into the airways, which leads to proteolytic enzymes such as neutrophil elastase and matrix metalloproteinases release, resulting in airway matrix destruction. …”
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    Neutrophils to Lymphocyte Ratio as a Biomarker in Bronchiectasis Exacerbation: A Retrospective Study
  5. 487445
    “…HIV-induced immune impairment heightened risk of opportunistic infection and can worsen nutritional status of children. HIV infection often leads to nutritional deficiencies through decreased food intake, mal-absorption and increased utilization and excretion of nutrients, which in turn can hasten death. …”
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    Magnitude of underweight, wasting and stunting among HIV positive children in East Africa: A systematic review and meta-analysis
  6. 487446
    “…Functional survival was affected by accumulation of holes, leading to users discarding nets. Protective efficacy also significantly differed between products as they aged. …”
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    Comparative functional survival and equivalent annual cost of 3 long-lasting insecticidal net (LLIN) products in Tanzania: A randomised trial with 3-year follow up
  7. 487447
    “…BACKGROUND: Antimicrobial resistance (AMR) is a serious global health threat and leads to a huge challenge to infectious diseases (ID) treatment. …”
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    The Effectiveness of Clinical Pharmacist-Led Consultation in the Treatment of Infectious Diseases: A Prospective, Multicenter, Cohort Study
  8. 487448
    “…BACKGROUND: Exposure to poor air quality leads to increased premature mortality from cardiovascular and respiratory diseases. …”
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    Short-term and long-term health impacts of air pollution reductions from COVID-19 lockdowns in China and Europe: a modelling study
  9. 487449
    “…Due to tumor intrinsic and/or extrinsic factors, the density and function of CD8(+) tumor-infiltrating lymphocytes (TILs) could be compromised, leading to poor prognosis and survival. METHODS: Using RNA-Seq, transcriptomes of sorted CD3(+)CD8(+) TILs from treatment-naïve colorectal cancer (CRC) patients at advanced stages (III and IV) were compared with those from patients with early stages (I and II). …”
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    Differential gene expression of tumor-infiltrating CD8(+) T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis
  10. 487450
    por Yan, Li, Sun, Jide, Xu, Xiuyu, Huang, Shifeng
    Publicado 2020
    “…Rectal colonization with CPE is a risk factor for bacterial translocation leading to subsequent endogenous CPE infections. This prospective observational study was aimed to investigate the prevalence and epidemiology of rectal colonization of CPE, the carbapenemase genotypes, and to identify the independent risk factors for the acquisition of CPE colonization in high-risk patients from ICU and HSCT wards in a university hospital in China. …”
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    Epidemiology and risk factors of rectal colonization of carbapenemase-producing Enterobacteriaceae among high-risk patients from ICU and HSCT wards in a university hospital
  11. 487451
    “…BACKGROUND: High, sustained adherence to HIV antiretroviral therapy (ART) is critical for achieving viral suppression, which in turn leads to important individual health benefits and reduced secondary viral transmission. …”
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    Factors Affecting the Implementation of Electronic Antiretroviral Therapy Adherence Monitoring and Associated Interventions for Routine HIV Care in Uganda: Qualitative Study
  12. 487452
    “…The disease mainly affects the respiratory system of the patient, in particular, the lungs, which leads to patients presenting with acute respiratory distress syndrome and acute respiratory failure, with 5-15% of patients requiring observation in the intensive care unit (ICU) with respiratory support in the form of ventilation. …”
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    Role of Biochemical Markers in Invasive Ventilation of Coronavirus Disease 2019 Patients: Multinomial Regression and Survival Analysis
  13. 487453
    “…CONCLUSIONS: Our suggested echocardiographic approach could be used to potentially reduce the frequency of “doubtful” classification and increase the accuracy in predicting elevated left ventricular filling pressure leading to a decrease in the number of invasive assessment made by right heart catheterization.…”
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    Echocardiography to estimate high filling pressure in patients with heart failure and reduced ejection fraction
  14. 487454
    “…Hepatocellular carcinoma (HCC) is a leading cause of mortality. Checkpoint inhibitors of programmed cell death protein‐1 (PD‐1) and programmed death‐ligand 1 (PD‐L1) have shown great efficacy, but lack biomarkers that predict response. …”
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    Hepatocellular Carcinoma–Circulating Tumor Cells Expressing PD‐L1 Are Prognostic and Potentially Associated With Response to Checkpoint Inhibitors
  15. 487455
    “…A systematic assessment of ER, PR and HER2 status is feasible and may help tailoring and optimise the treatment of patients with breast cancer in low-resource settings, potentially leading to survival gains in this underserved population.…”
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    Breast cancer subtypes: implications for the treatment and survival of patients in Africa—a prospective cohort study from Mozambique
  16. 487456
    “…BACKGROUND: Breast cancer is the leading cause of mortality among women worldwide. …”
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    Breast Self-Examination System Using Multifaceted Trustworthiness: Observational Study
  17. 487457
    “…NLP’s sensitivity to changes in emotional tone, values, and personality strengths suggests the efficacy of NLP as a leading indicator of treatment progress.…”
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    Natural Language Processing Tools for Assessing Progress and Outcome of Two Veteran Populations: Cohort Study From a Novel Online Intervention for Posttraumatic Growth
  18. 487458
    “…CONCLUSIONS: Pooled data from many sources suggests that the ASO for d-TGA leads to high rates of survival in the short, medium, and long term.…”
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    Outcomes after corrective surgery for congenital dextro-transposition of the arteries using the arterial switch technique: a scoping systematic review
  19. 487459
    “…BACKGROUND: Untreated congenital blindness through cataracts leads to lasting visual brain system changes, including substantial alterations of extrastriate visual areas. …”
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    An electrophysiological biomarker for the classification of cataract-reversal patients: A case-control study
  20. 487460
    “…Storyboards were created during the design phase, leading to prototypes of “Motivate Me” and “My Activity Programme.” …”
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    Smartphone Apps to Support Falls Rehabilitation Exercise: App Development and Usability and Acceptability Study
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