“…Since mid-1990s, the HIV-1 epidemic in Russia has started to grow substantially due to the multiple HIV-1 outbreaks among persons who inject drugs (PWID) leading to expansion of the HIV-1 sub-subtype A6 (former Soviet Union (FSU) subtype A). …”
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“…However, the pathogenesis leading to AF in the context of MAFLD remains unclear. …”
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“…BACKGROUND: Physical inactivity is a leading risk factor for many health conditions, including cardiovascular disease, diabetes, and cancer; therefore, increasing physical activity (PA) is a public health priority. …”
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“…OBJECTIVE: This study examines online public discourse and sentiment toward dementia among the Chinese public on a leading Chinese social media platform Weibo. Specifically, this study aims to (1) assess and examine public discourse and sentiment toward dementia among the Chinese public, (2) determine the extent to which dementia-related discourse and sentiment vary among different user groups (ie, government, journalists/news media, scientists/experts, and the general public), and (3) characterize temporal trends in public discourse and sentiment toward dementia among different user groups in China over the past decade. …”
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“…Introduction In polytrauma patients, it is crucial to identify the severity of the injuries to ensure patient safety and survival. Polytrauma leads to hypotension and hypoperfusion, which results in an anaerobic metabolism with acidosis and a decrease in base excess. …”
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“…FW is generally considered to have high volatile solids which hydrolyze rapidly lowering pH arising from excess production of Hydrogen which in presence of CO(2) and acetogenic bacteria leads to more production of acetate, formate and other long chain fatty acids which inhibits methanogenesis as a result of rapid acidification. …”
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“…In CC, tumor-derived exosomes activated STING signaling in tumor-infiltrated T cells by exosomal TGF-β, cyclic GMP-AMP synthase and 2’-3’-cGAMP, leading to iTreg expansion. CONCLUSIONS: These findings highlight a novel mechanism for iTreg expansion mediated by tumor-derived exosome-activated T cell-intrinsic STING signal, and provide a rationale for developing immunotherapeutic strategies targeting STING signal in CC.…”
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“…Various studies reveal that invasive fungal infections have been the leading cause of death in 25%-73.7% of patients. Among these invasive fungal infections, Mucor spp. were detected in 77.8% patient, Aspergillus fumigatus in 30.6% while 8.3% showed mixed infection with both the fungi. …”
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“…However, the long-term use of AGP leads to various adverse effects, such as antimicrobial resistance and food drug residues, and threatens public safety. …”
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“…BACKGROUND: Cervical cancer is a leading cause of mortality among women globally. Approaches to reduce cervical cancer incidence and mortality are “screen-and-treat,” where positive primary test only is used in the treatment and “screen, triage and treat,” where treatment is based on positive primary and triage tests with/without histological analysis. …”
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“…CONCLUSION: Systemic histoplasmosis is typically acquired through inhalation of microconidia or small hyphal elements in soil contaminated with bird and bat droppings leading to primary infection. This patient only manifested bilateral adrenal involvement with nonspecific symptoms.…”
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“…CONCLUSIONS: These results indicate that HSCs are capable of phagocytosing H. capsulatum but do not affect its survival; moreover, this fungal pathogen could induce changes in the expression of pattern-recognition receptors (PRRs), especially TLR2 and Dectin-1, and could subsequently activate the HSCs leading to the expression of inflammatory mediators as well as affecting the viability of these stem cells. …”
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“…POSTER SESSION 2, SEPTEMBER 22, 2022, 12:30 PM - 1:30 PM:   OBJECTIVE: We present ten tinea incognito (TI) patients caused by Trichophyton rubrum combined with a review of the characteristics of tinea incognito infections reported worldwide over the past 20 years, leading to clinical requirements for diagnosis and treatment. …”
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“…This is supported in chronic pain research where ACT leads to improved functioning, particularly in those with higher ASD traits. …”
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“…Although Candida species remain the leading cause of invasive fungal infections (IFI), there are certain rare species like C. pelliculosa, that can cause fungemia. …”
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“…INTRODUCTION: Cryptococcal meningitis is the most frequent cause of adult meningitis in areas with a high prevalence of human immunodeficiency virus (HIV) and is one of the leading causes of HIV-related deaths worldwide. Cryptococcus gattii, the lesser prevalent species, ‘conventionally’ known to affect the non-HIV and otherwise immunocompetent population, may also cause disseminated infection in HIV patients. …”
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“…BACKGROUND: Facioscapulohumeral dystrophy (FSHD) is a progressive muscle dystrophy disorder leading to significant disability. Currently, FSHD symptom severity is assessed by clinical assessments such as the FSHD clinical score and the Timed Up-and-Go test. …”
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“…BACKGROUND: Knee osteoarthritis (OA) is the most common form of OA and a leading cause of disability worldwide. Chronic pain and functional loss secondary to knee OA put patients at risk of developing depression, which can also impair their treatment response. …”
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“…BACKGROUND: Depression is one of the most prevalent mental disorders and a leading cause of disability, disproportionately affecting specific groups, such as patients with noncommunicable diseases. …”
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“…Saudis’ quality of life has decreased due to the recent rise in diabetes-related mortality and illnesses. Hence, leading healthy lives requires patients to have positive attitudes and self-awareness, which will eventually contribute to reducing diabetes mellites-related complications. …”
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