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  1. 487921
    “…Duchenne Muscular Dystrophy (DMD) is a lethal disease caused by mutations in dystrophin encoding gene, causing progressive degeneration of cardiac, respiratory, and skeletal muscles leading to premature death due to cardiac and respiratory failure. …”
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  2. 487922
  3. 487923
    “…CONCLUSION: We present a case of right eye episcleritis occurring 24 hours post zoledronic acid infusion leading to significant ocular discomfort and concern for the patient. …”
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  4. 487924
    “…It can cause hypercalcemia leading to nephrocalcinosis, nephrolithiasis, chronic kidney disease, and hyperparathyroidism. …”
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  5. 487925
    “…Her next-generation sequencing confirmed HCS with a mutation at nucleotide 6758G>A, leading to Trp2253Ter amino acid in NOTCH2 gene annotated as pathogenic. …”
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  6. 487926
    “…It converts vitamin D to its active form 1,25(OH)2 vitamin D causing its excess, leading to hypercalcemia. Other potential causes of hypercalcemia such as malignancy must be ruled out as seen in our patient who had classic B symptoms with imaging suggestive of lymphoma. …”
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  7. 487927
    “…These agents decrease the blood glucose level by increasing urinary glucose excretion leading to a reduction in insulin secretion from the pancreatic β-cells. …”
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  8. 487928
    “…The amino acid 5-aminolevulinic acid (5-ALA) is the first heme biosynthetic precursor and the administration of 5-ALA combined with sodium ferrous citrate (SFC) enhance heme production, leading to improvement of mitochondrial function and ATP production. …”
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  9. 487929
    “…Specifically, while some patients may experience suboptimal response to combination anti-obesity therapies, it may be that the addition of GLP1-RAs to such regimens, namely semaglutide, can provide a synergistic effect leading to substantial weight loss approaching that achieved from metabolic/bariatric surgery. …”
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  10. 487930
    “…Inpatient evaluation revealed a morning Cortisol of 1.4 ug/dL (n 4.8-19.5 ug/dL), aldosterone <3 ng/dL (n <16 ng/dL), and ACTH 1071 pg/mL (n 7.2-63.3 pg/mL) leading to the diagnosis of primary adrenal insufficiency. …”
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  11. 487931
    “…Additionally, SGLT2i may directly stimulate glucagon release leading to increased lipolysis. There have been number of case reports suggestive of EuDKA after gastric bypass surgery in association with use of SGLT2i. …”
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  12. 487932
    “…HYPOTHESIS: Diabetes has been associated with higher frequency use of emergency department (ED) services and inpatient admission, leading to higher costs associated with diabetes. …”
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  13. 487933
    “…Excessive secretion of PTH leads to elevated serum levels of alkaline phosphatase as well as calcium and decreased serum inorganic phosphate level. …”
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  14. 487934
    por Cannon, Sophie M, Angell, Trevor E
    Publicado 2022
    “…Recent literature suggests that acute ingestion of exogenous ketones leads to increased blood beta-hydroxybutyrate and decreased blood glucose1. …”
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  15. 487935
    por Patel, Toral, Arora, Gunjan
    Publicado 2022
    “…Geriatric Type 1 DM presents great challenges in management as it combines micro and macro vascular complications of long standing DM with geriatric syndrome - concurrent comorbidities, cognitive losses of various degrees, vision and hearing loss, loss autonomic and hormonal counter-regulation, and progressive frailty leading to severe glycemic instability makes self management of DM near impossible. …”
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  16. 487936
    “…However glucocorticoid excess is known to cause negative metabolic effects including hyperglycaemia, muscle atrophy and fat accumulation, ultimately leading to Cushing's Syndrome. The effect on energy metabolism and metabolic rate remains undefined and merits investigation in both male and female mice. …”
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  17. 487937
    “…Among critically ill patients, there is usually impairment of the hypothalamic-pituitary- adrenal axis, leading to a condition known as critical illness-related corticosteroid insufficiency (CIRCI). …”
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  18. 487938
    “…Recent literature suggests that acute ingestion of exogenous ketones leads to increased blood beta-hydroxybutyrate and decreased blood glucose1. …”
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  19. 487939
    “…Patients hospitalized with SIADH, and comorbid AF had higher inpatient mortality, LOS, THC, which may be secondary to multiple electrolyte abnormalities and fluid imbalances associated with SIADH leading to a worsening of the AF. Furthermore, these patients had higher odds of septic shock and ARF. …”
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  20. 487940
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