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488321por Rosa-Diez, Guillermo, Gonzalez-Bedat, Maria, Pecoits-Filho, Roberto, Marinovich, Sergio, Fernandez, Sdenka, Lugon, Jocemir, Poblete-Badal, Hugo, Elgueta-Miranda, Susana, Gomez, Rafael, Cerdas-Calderon, Manuel, Almaguer-Lopez, Miguel, Freire, Nelly, Leiva-Merino, Ricardo, Rodriguez, Gaspar, Luna-Guerra, Jorge, Bochicchio, Tomasso, Garcia-Garcia, Guillermo, Cano, Nuria, Iron, Norman, Cuero, Cesar, Cuevas, Dario, Tapia, Carlos, Cangiano, Jose, Rodriguez, Sandra, Gonzalez, Haydee, Duro-Garcia, Valter“…Diabetes remained the leading cause of ESRD. The most frequent causes of death were cardiovascular (45%) and infections (22%). …”
Publicado 2014
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488322por Atukunda, Esther C., Siedner, Mark J., Obua, Celestino, Mugyenyi, Godfrey R., Twagirumukiza, Marc, Agaba, Amon G.“…BACKGROUND: Postpartum hemorrhage (PPH) is a leading cause of maternal death in sub-Saharan Africa. …”
Publicado 2014
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488323por Arathoon, Eduardo, Bhorat, Asad, Silaghi, Rodica, Crauwels, Herta, Lavreys, Ludo, Tambuyzer, Lotke, Vanveggel, Simon, Opsomer, Magda“…Incidence of grade 3–4 AEs was 13%, serious AEs 5% (no rashes; none ETR related), AEs leading to discontinuation 4%, AEs possibly related to ETR 23% and AEs of interest: rash (any type) 4%, hepatic 6% and neuropsychiatric 3%. …”
Publicado 2014
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488324“…The increase rate of utilization of branched-chain amino acids (BCAA) by muscle is reduced to its plasma concentration during prolonged exercise leading to glycogen. BCAA supplementation would reduce the serum activities of intramuscular enzymes associated with muscle damage. …”
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488325“…The signal-to-noise ratio in higher frequencies decreased faster than in lower frequencies, leading to the maximum signal-to-noise ratio shift form 3.2–4.0 kHz in neonates to 1.5 kHz in adults, and further decreasing the total TEOAE response level. …”
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488326por Coupland, Carol, Hill, Trevor, Morriss, Richard, Arthur, Antony, Moore, Michael, Hippisley-Cox, Julia“…Mirtazapine, venlafaxine, and trazodone were associated with the highest rates of suicide and attempted suicide or self harm, but the number of suicide events was small leading to imprecise estimates. As this is an observational study the findings may reflect indication biases and residual confounding from severity of depression and differing characteristics of patients prescribed these drugs. …”
Publicado 2015
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488327por Wyrsch, Ethan, Chowdhury, Piklu Roy, Abraham, Sam, Santos, Jerran, Darling, Aaron E, Charles, Ian G, Chapman, Toni A, Djordjevic, Steven P“…BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) are a major economic threat to pig production globally, with serogroups O8, O9, O45, O101, O138, O139, O141, O149 and O157 implicated as the leading diarrhoeal pathogens affecting pigs below four weeks of age. …”
Publicado 2015
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488328por Greco, Eliana, Aita, Ada, Galozzi, Paola, Gava, Alessandra, Sfriso, Paolo, Negm, Ola H, Tighe, Patrick, Caso, Francesco, Navaglia, Filippo, Dazzo, Emanuela, De Bortoli, Marzia, Rampazzo, Alessandra, Obici, Laura, Donadei, Simona, Merlini, Giampaolo, Plebani, Mario, Todd, Ian, Basso, Daniela, Punzi, Leonardo“…CONCLUSIONS: The novel S59P mutation leads to defective cellular trafficking and to constitutive activation of TNF-R1. …”
Publicado 2015
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488329por Malvankar-Mehta, Monali S., Chen, Yufeng Nancy, Iordanous, Yiannis, Wang, Wan Wendy, Costella, John, Hutnik, Cindy M. L.“…BACKGROUND: Glaucoma is a leading cause of irreversible blindness. It is firmly entrenched in the traditional treatment paradigm to start with pharmacotherapy. …”
Publicado 2015
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488330por Volker, Daniëlle, Zijlstra-Vlasveld, Moniek C, Anema, Johannes R, Beekman, Aartjan TF, Brouwers, Evelien PM, Emons, Wilco HM, van Lomwel, A Gijsbert C, van der Feltz-Cornelis, Christina M“…BACKGROUND: Common mental disorders are strongly associated with long-term sickness absence, which has negative consequences for the individual employee’s quality of life and leads to substantial costs for society. It is important to focus on return to work (RTW) during treatment of sick-listed employees with common mental disorders. …”
Publicado 2015
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488331por Ke, Tao, Cao, Huihui, Huang, Junyan, Hu, Fan, Huang, Jin, Dong, Caihua, Ma, Xiangdong, Yu, Jingyin, Mao, Han, Wang, Xi, Niu, Qiuhong, Hui, Fengli, Liu, Shengyi“…BACKGROUND: Brassica napus is the third leading source of vegetable oil in the world after soybean and oil palm. …”
Publicado 2015
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488332por Rodriguez, Robert M., Langdorf, Mark I., Nishijima, Daniel, Baumann, Brigitte M., Hendey, Gregory W., Medak, Anthony J., Raja, Ali S., Allen, Isabel E., Mower, William R.“…BACKGROUND: Unnecessary diagnostic imaging leads to higher costs, longer emergency department stays, and increased patient exposure to ionizing radiation. …”
Publicado 2015
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488333“…OBJECTIVES: Osteochondral injury is associated with pain and/or dysfunction and has been implicated as a factor leading to early degenerative joint disease. Fresh osteochondral allograft (OCA) transplantation is a well-described surgical replacement therapy for patients with large osteochondral defects. …”
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488334por Heyworth, Benton E., May, Collin, Carsen, Sasha, Donohue, Kyna, Miller, Patricia, Kramer, Dennis E., Kocher, Mininder S., Bae, Donald S.“…The rate of symptomatic implants was 13% in the operative group (leading to plate removal in 9% cases), while the rate of symptomatic malunion was 2% in the nonoperative group. …”
Publicado 2014
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488335por Kong, Ling-An, Wu, Du-Qing, Huang, Wen-Kun, Peng, Huan, Wang, Gao-Feng, Cui, Jiang-Kuan, Liu, Shi-Ming, Li, Zhi-Gang, Yang, Jun, Peng, De-Liang“…Infection assays showed that VP1620 failed to block penetration of H. avenae but disturbed the transition of developmental stages, leading to a significant reduction in cyst formation. …”
Publicado 2015
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488336por Foley, Cathriona, Chapwanya, Aspinas, Callanan, John J., Whiston, Ronan, Miranda-CasoLuengo, Raúl, Lu, Junnan, Meijer, Wim G., Lynn, David J., O’ Farrelly, Cliona, Meade, Kieran G.“…All cows experience bacterial influx into the uterus after calving; however a significant proportion fail to clear infection leading to the development of cytological endometritis (CE) and compromised fertility. …”
Publicado 2015
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488337Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesispor Hufbauer, Martin, Cooke, James, van der Horst, Gijsbertus T. J., Pfister, Herbert, Storey, Alan, Akgül, Baki“…High-risk patient groups, such as organ transplant recipients (OTRs) frequently exhibit field cancerization at UV exposed body sites from which multiple human papillomavirus (HPV)-associated cSCCs develop rapidly, leading to profound morbidity and increased mortality. …”
Publicado 2015
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488338por Liu, Dan, Deng, Que, Sun, Limin, Wang, Tao, Yang, Zhengyan, Chen, Hongyu, Guo, Liang, Liu, Yanjun, Ma, Yuanfang, Guo, Ning, Shi, Ming“…The treatment with MEK1/2 inhibitors PD98059 or PD184352 effectively restored the let-7f level, suggesting that Her2-overexpression-mediated ERK constitutive activation inhibited let-7f, leading to the upregulation of the β2-AR expression. …”
Publicado 2015
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488339por Shukla, Priyank, Vogl, Claus, Wallner, Barbara, Rigler, Doris, Müller, Mathias, Macho-Maschler, Sabine“…A central pathway in Ras induced EMT is TGFβ signaling, which leads to differential regulation of many target genes, including miRNAs. …”
Publicado 2015
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488340“…This mutation disrupts photoreceptor polarity and leads to retinal degeneration. It was hypothesized that the G-protein receptor kinase 1 knockouts (Grk1(−/−)), which were based on the B6N strain, would exhibit abnormal morphological phenotypes in their offspring not related to GRK1’s major phosphorylation function. …”
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