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  1. 488421
    “…BACKGROUND: Colorectal cancer (CRC) is the third most common type of cancer and leading cause of death worldwide. Major risk factors involved in the development of CRC are increased dietary sources, genetics, and increasing age. …”
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    Implications of Isoprostanes and Matrix Metalloproteinase-7 Having Potential Role in the Development of Colorectal Cancer in Males
  2. 488422
    “…BACKGROUND: Suicide is a leading cause of death among 10- to 19-year-olds in the United States, with 5% to 8% attempting suicide each year. …”
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    Mobile Phone Intervention to Reduce Youth Suicide in Rural Communities: Field Test
  3. 488423
    “…Finally, most of the well-known (i.e., blood pressure, heart rate, waist to hip, triglycerides, and HDL-C) and novel CVD risk factors [i.e., inflammation markers (C-reactive protein, leukocytes, and chemoattractant protein-1), fibrinogen, and glucose homeostasis (i.e., insulin resistance, and glycated hemoglobin)] are substantially (p < 0.0001) altered in severe-obese-LH: 0–2 vs overweight-LH: 0–2, pointing to the fact that obesity leads to worsen the CVD/T2D risk factor profile. …”
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    Sterol 27-Hydroxylase Polymorphism Significantly Associates With Shorter Telomere, Higher Cardiovascular and Type-2 Diabetes Risk in Obese Subjects
  4. 488424
    “…CONCLUSIONS: Participation in FFIT under research and routine conditions leads to long-term weight loss and improvements in physical activity and diet. …”
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    Long-term weight loss trajectories following participation in a randomised controlled trial of a weight management programme for men delivered through professional football clubs: a longitudinal cohort study and economic evaluation
  5. 488425
    por Mellor, David J.
    Publicado 2018
    “…Third, underpinned by the incorrect conclusion that puppies are conscious at the usual docking age, it is argued here that the well-validated human emotional drive or desire to care for and protect vulnerable young, leads observers to misread striking docking-induced behaviour as indicating that the puppies consciously experience significant acute pain and distress. …”
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    Tail Docking of Canine Puppies: Reassessment of the Tail’s Role in Communication, the Acute Pain Caused by Docking and Interpretation of Behavioural Responses
  6. 488426
    “…BACKGROUND: Bone metastasis is a leading cause of morbidity and mortality in advanced prostate cancer (PCa). …”
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    Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling
  7. 488427
    por Saha, Samir K, Schrag, Stephanie J, El Arifeen, Shams, Mullany, Luke C, Shahidul Islam, Mohammad, Shang, Nong, Qazi, Shamim A, Zaidi, Anita K M, Bhutta, Zulfiqar A, Bose, Anuradha, Panigrahi, Pinaki, Soofi, Sajid B, Connor, Nicholas E, Mitra, Dipak K, Isaac, Rita, Winchell, Jonas M, Arvay, Melissa L, Islam, Maksuda, Shafiq, Yasir, Nisar, Imran, Baloch, Benazir, Kabir, Furqan, Ali, Murtaza, Diaz, Maureen H, Satpathy, Radhanath, Nanda, Pritish, Padhi, Bijaya K, Parida, Sailajanandan, Hotwani, Aneeta, Hasanuzzaman, M, Ahmed, Sheraz, Belal Hossain, Mohammad, Ariff, Shabina, Ahmed, Imran, Ibne Moin, Syed Mamun, Mahmud, Arif, Waller, Jessica L, Rafiqullah, Iftekhar, Quaiyum, Mohammad A, Begum, Nazma, Balaji, Veeraraghavan, Halen, Jasmin, Nawshad Uddin Ahmed, A S M, Weber, Martin W, Hamer, Davidson H, Hibberd, Patricia L, Sadeq-ur Rahman, Qazi, Mogan, Venkat Raghava, Hossain, Tanvir, McGee, Lesley, Anandan, Shalini, Liu, Anran, Panigrahi, Kalpana, Abraham, Asha Mary, Baqui, Abdullah H
    Publicado 2018
    “…Mean incidence of bacterial infections was 13·2 (95% credible interval [CrI] 11·2–15·6) per 1000 livebirths and of viral infections was 10·1 (9·4–11·6) per 1000 livebirths. The leading pathogen was respiratory syncytial virus (5·4, 95% CrI 4·8–6·3 episodes per 1000 livebirths), followed by Ureaplasma spp (2·4, 1·6–3·2 episodes per 1000 livebirths). …”
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    Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study
  8. 488428
    “…Autosomal recessive spinal muscular atrophy (SMA), the leading genetic cause of infant lethality, is caused by homozygous loss of the survival motor neuron 1 (SMN1) gene. …”
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    CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis
  9. 488429
    “…Ectopic overexpression of miR-22 repressed the expression of FOXP1 and HDAC4, leading to a marked induction of acetylation of HDAC4 target histones. …”
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    A dual role of miR-22 modulated by RelA/p65 in resensitizing fulvestrant-resistant breast cancer cells to fulvestrant by targeting FOXP1 and HDAC4 and constitutive acetylation of p53 at Lys382
  10. 488430
    “…Qualitative studies found that while social media provides a space to disclose minority experiences and share ways to cope and get support, constant surveillance of one’s social media profile can become a stressor, potentially leading to depression. In most studies, sexual minority participants were identified inconsistently. …”
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    For Better or for Worse? A Systematic Review of the Evidence on Social Media Use and Depression Among Lesbian, Gay, and Bisexual Minorities
  11. 488431
    “…OBJECTIVES: In the setting of ulnar collateral ligament (UCL) injury, surgical reconstruction of the UCL is not always selected, as it leads to a prolonged recovery time and return to play rates between 67-95%. …”
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    Comparative Analysis of the Nonoperative Treatment of Elbow Ulnar Collateral Ligament Injuries in Professional Baseball Players with and without Platelet-Rich Plasma
  12. 488432
    “…BACKGROUND: Myocardial infarction (MI) leads to complex changes in left ventricular (LV) haemodynamics that are linked to clinical outcomes. …”
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    Left ventricular blood flow kinetic energy after myocardial infarction - insights from 4D flow cardiovascular magnetic resonance
  13. 488433
    Publicado 2018
    “…We found substantial inter-state heterogeneity in the age-standardised incidence rate of the different types of cancers in 2016, with a 3·3 times to 11·6 times variation for the four most frequent cancers (lip and oral, breast, lung, and stomach). Tobacco use was the leading risk factor for cancers in India to which the highest proportion (10·9%) of cancer DALYs could be attributed in 2016. …”
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    The burden of cancers and their variations across the states of India: the Global Burden of Disease Study 1990–2016
  14. 488434
    “…BACKGROUND: One of the key risk factors for cardiovascular disease is hypertension. Hypertension, which leads to heart attacks and strokes, already affects one billion people worldwide, making it a global public health issue. …”
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    Prevalence, incidence, predictors, treatment, and control of hypertension among HIV-positive adults on antiretroviral treatment in public sector treatment programs in South Africa
  15. 488435
    por Körner, Julia
    Publicado 2018
    “…The results give insight into the complex interplay between the individual subsystem’s properties and the frequency matching, leading to a rather large parameter space for the co-resonant system’s effective properties. …”
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    Effective sensor properties and sensitivity considerations of a dynamic co-resonantly coupled cantilever sensor
  16. 488436
    “…CONCLUSIONS: Our findings revealed that CS exposure regulates inflammatory responses in monocyte/macrophages from LCS-PTB patients via upregulating miR-196b-5p, and further understanding of the specific role of miR-196b-5p in inflammatory responses mightfacilitate elucidating the pathogenesis of LCS-PTB, thus leading to the development of new therapeutic strategies for PTB patients with long-term cigarette smoking. …”
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    Upregulation of miR-196b-5p attenuates BCG uptake via targeting SOCS3 and activating STAT3 in macrophages from patients with long-term cigarette smoking-related active pulmonary tuberculosis
  17. 488437
    Publicado 2018
    “…Of the DALYs due to COPD in India in 2016, 53·7% (43·1–65·0) were attributable to air pollution, 25·4% (19·5–31·7) to tobacco use, and 16·5% (14·1–19·2) to occupational risks, making these the leading risk factors for COPD. INTERPRETATION: India has a disproportionately high burden of chronic respiratory diseases. …”
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    The burden of chronic respiratory diseases and their heterogeneity across the states of India: the Global Burden of Disease Study 1990–2016
  18. 488438
    “…Secondary data analysis includes the analysis of 6 distinct databases, each covered by a formal memorandum of agreement between Northern Arizona University and the designated institution: (1) the Superior Court of Arizona Public Case Finder database; (2) North Country Health Care; (3) Health Choice Integrated Care; (4) Criminal Justice Information Services; (5) Correctional Electronic Medical Records; and (6) iLEADS. We will perform data integration processes using an automated honest broker design. …”
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    Health Disparities and Converging Epidemics in Jail Populations: Protocol for a Mixed-Methods Study
  19. 488439
    “…CONCLUSIONS: Although we do not have a gold standard indicating which algorithm produces the most optimal set of peer change agents, the lower sensitivity of eigenvector centrality to key assumptions leads us to conclude that it may be preferable. The methods we employed to address the challenges in using Facebook networks may prove timely, given the rapidly increasing interest in using online social networks to improve population health.…”
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    Using Partially-Observed Facebook Networks to Develop a Peer-Based HIV Prevention Intervention: Case Study
  20. 488440
    “…Since low adherence to psychotherapy leads to a waste of therapeutic resources and risky treatment abortion in MI-ANXDEP patients, identifying early predictors for adherence is potentially valuable for effective targeted care. …”
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    Predicting Adherence to Internet-Delivered Psychotherapy for Symptoms of Depression and Anxiety After Myocardial Infarction: Machine Learning Insights From the U-CARE Heart Randomized Controlled Trial
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