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488781por Mclaughlin, Matthew, Duff, Jed, McKenzie, Tom, Campbell, Elizabeth, Sutherland, Rachel, Wiggers, John, Wolfenden, Luke“…OBJECTIVE: The 2 objectives were to (1) describe the usage of the PA4E1 program website by in-school champions (PE teachers leading the program within their schools) and PE teachers using quantitative methods; (2) examine the usage, subjective experience, and usability of the PA4E1 program website from the perspective of in-school champions using mixed methods. …”
Publicado 2021
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488782por do Espírito Santo, Marcelo Prudente, Faria, Caroline Silvério, Solla, Davi Jorge Fontoura, Pipek, Leonardo Zumerkorn, Belon, Alessandro Rodrigo, Jeng, Brasil Ping, de Andrade, Almir Ferreira, Teixeira, Manoel Jacobsen, Paiva, Wellingson Silva“…BACKGROUND: Intracranial hypertension (ICH) is a common final pathway of most neurosurgical pathologies and leads to poor prognosis if not detected and treated properly. …”
Publicado 2021
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488783por Mohammed, Abdi, Faustinelli, Paola C., Chala, Alemayehu, Dejene, Mashilla, Fininsa, Chemeda, Ayalew, Amare, Ojiewo, Chris O., Hoisington, David A., Sobolev, Victor S., Martínez-Castillo, Jaime, Arias, Renee S.“…BACKGROUND: Aspergillus species cause aflatoxin contamination in groundnut kernels, being a health threat in agricultural products and leading to commodity rejection by domestic and international markets. …”
Publicado 2021
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488784por Hlaoperm, Chularat, Choowongkomon, Kiattawee, Pruksakorn, Chantima, Rattanasrisomporn, Jatuporn“…BACKGROUND AND AIM: Helicobacter pylori is an important pathogen in humans and animals involved in chronic gastritis, leading to the development of gastric cancer. Urease produced by H. pylori is an enzyme that promotes bacterial colonization and can be used clinically as a biomarker of H. pylori infection as part of a rapid urease test (RUT). …”
Publicado 2021
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488785por He, Vincent Yaofeng, Leckning, Bernard, Malvaso, Catia, Williams, Tamika, Liddle, Leanne, Guthridge, Steven“…BACKGROUND: Numerous studies have demonstrated a strong link between child maltreatment and subsequent youth offending, leading to calls for early intervention initiatives. …”
Publicado 2021
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488786por Azul, Anabela Marisa, Almendra, Ricardo, Quatorze, Marta, Loureiro, Adriana, Reis, Flávio, Tavares, Rui, Mota-Pinto, Anabela, Cunha, António, Rama, Luís, Malva, João Oliveira, Santana, Paula, Ramalho-Santos, João“…BACKGROUND: Non-communicable diseases are a leading cause of health loss worldwide, in part due to unhealthy lifestyles. …”
Publicado 2021
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488787“…BACKGROUND: Midwives have a high risk of work-related musculoskeletal disorders (WMSDs), which are the leading cause of pain and disability. However, the association between job stress and WMSDs among midwives has not been studied. …”
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488788por Sonnenfeld, Nancy, Li, Jiaqi, Lichtenfeld, Jake, Shang, Kevin, Herzer, Kurt, Flemming, Robert, Yu, Ping, Monteiro, Anita, McGann, Paul, Fleisher, Lee“…RESEARCH OBJECTIVE: In 2020 COVID‐19 became the leading cause of death in the United States,[1] with nursing home (NH) residents accounting for approximately 40% of all COVID‐19 deaths.[2] To help NHs combat COVID‐19, the Centers for Medicare and Medicaid Services (CMS) directed targeted response (TR) interventions through its twelve Quality Improvement Network – Quality Improvement Organization (QIN‐QIOs) contractors. …”
Publicado 2021
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488789“…In particular, even the addition of only 5% SCG leads to a significant reduction of the thermal conductivity and consequently to a greater insulating performance. …”
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488790por Demissie, Birhanu Wondimeneh, Amele, Esayas Aydiko, Yitayew, Yibeltal Asmamaw, Yalew, Zemen Mengesha“…BACKGROUND: Lower respiratory infections are a leading cause of morbidity and mortality worldwide, particularly in children younger than 5 years. …”
Publicado 2021
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488791por Habbous, Steven, Yermakhanova, Olga, Forster, Katharina, Holloway, Claire M. B., Darling, Gail“…IMPORTANCE: Esophageal cancer remains one of the most deadly cancers, ranking sixth highest among cancers leading to the greatest years of life lost. OBJECTIVE: To determine how patients with esophageal cancer are diagnosed and treated in Ontario’s regionalized thoracic surgery centers. …”
Publicado 2021
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488792por Rutter, Lauren A, Thompson, Holly M, Howard, Jacqueline, Riley, Tennisha N, De Jesús-Romero, Robinson, Lorenzo-Luaces, Lorenzo“…As this was a cross-sectional study, we cannot conclude that social media use causes internalizing symptoms or that physical activity leads to decreased internalizing symptoms—there may be additional confounding variables producing the relationships we observed. …”
Publicado 2021
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488793por Zhang, Congcong, Röder, Jasmin, Scherer, Anne, Bodden, Malena, Pfeifer Serrahima, Jordi, Bhatti, Anita, Waldmann, Anja, Müller, Nina, Oberoi, Pranav, Wels, Winfried S“…Furthermore, NKAB-ErbB2 synergized with NK-92 cells or primary T cells engineered to express an NKG2D-CD3ζ chimeric antigen receptor (NKAR), leading to targeted cell killing and greatly enhanced antitumor activity, which remained unaffected by soluble MICA known as an inhibitor of NKG2D-mediated natural cytotoxicity. …”
Publicado 2021
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488794por Oliva, Marc, Chepeha, Douglas, Araujo, Daniel V, Diaz-Mejia, J. Javier, Olson, Peter, Prawira, Amy, Spreafico, Anna, Bratman, Scott V, Shek, Tina, de Almeida, John, R Hansen, Aaron, Hope, Andrew, Goldstein, David, Weinreb, Ilan, Smith, Stephen, Perez-Ordoñez, Bayardo, Irish, Jonathan, Torti, Dax, Bruce, Jeffrey P., Wang, Ben X., Fortuna, Anthony, Pugh, Trevor J., Der-Torossian, Hirak, Shazer, Ronald, Attanasio, Nickolas, Au, Qingyan, Tin, Antony, Feeney, Jordan, Sethi, Himanshu, Aleshin, Alexey, Chen, Isan, Siu, Lillian“…CONCLUSIONS: The SNOW study shows sitravatinib plus nivolumab is safe and leads to deep clinical and pathological responses in oral cavity carcinomas. …”
Publicado 2021
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488795por Hulbert-Williams, Nicholas J, Leslie, Monica, Hulbert-Williams, Lee, Koczwara, Bogda, Watson, Eila K, Hall, Peter S, Ashley, Laura, Coulson, Neil S, Jackson, Richard, Millington, Sue, Beatty, Lisa“…Previous trials have demonstrated that FMW is acceptable, highly adhered to, and effective in reducing the impact of distress on quality of life while leading to cost savings through health resource use reduction. …”
Publicado 2021
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488796por Zhang, Mengling, Liu, Jian, Zhang, Rui, Liang, Zengenni, Ding, Shenghua, Yu, Huanling, Shan, Yang“…Molecular docking and dynamics simulations found that NOB spontaneously bonded to human p53 protein, leading to the change of protein conformation. The intermolecular interaction between NOB and human p53 protein was further confirmed by UV-visible spectroscopy, fluorescence spectroscopy and circular dichroism. …”
Publicado 2021
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488797por da Silva Rosa, Simone C., Martens, Matthew D., Field, Jared T., Nguyen, Lucas, Kereliuk, Stephanie M., Hai, Yan, Chapman, Donald, Diehl-Jones, William, Aliani, Michel, West, Adrian R., Thliveris, James, Ghavami, Saeid, Rampitsch, Christof, Dolinsky, Vernon W., Gordon, Joseph W.“…Finally, we demonstrate that BNIP3L-induced mitophagy and impaired glucose uptake can be reversed by direct phosphorylation of BNIP3L by PRKA/PKA, leading to the translocation of BNIP3L from the mitochondria and sarcoplasmic reticulum to the cytosol. …”
Publicado 2020
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488798por Li, Rui, Zeng, Xin, Yang, Meihua, Feng, Jinmei, Xu, Xiaohui, Bao, Liming, Ye, Tingbo, Wang, Xin, Xue, Bingqian, Huang, Yi“…Moreover, we revealed that DPP-4i triggered ROS-NF-κB-dependent NLRP3 inflammasome activation in BC cells, leading to increase in inflammation cytokines such as interleukin (IL)-6, tumor necrosis factor alpha (TNF-α), vascular endothelial growth factor (VEGF), intercellular cell adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), IL-1β and IL-33, and MDSCs inductors granulocyte-macrophage colony-stimulating factor (GM-CSF), G-CSF, and M-CSF, which play a crucial role in the remodeling of tumor immune-suppressive microenvironment. …”
Publicado 2021
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488799por Anan, Tomomi, Kajiki, Shigeyuki, Oka, Hiroyuki, Fujii, Tomoko, Kawamata, Kayo, Mori, Koji, Matsudaira, Ko“…BACKGROUND: Musculoskeletal symptoms such as neck and shoulder pain/stiffness and low back pain are common health problems in the working population. They are the leading causes of presenteeism (employees being physically present at work but unable to be fully engaged). …”
Publicado 2021
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488800por Thabrew, Hiran, Stasiak, Karolina, Kumar, Harshali, Naseem, Tarique, Frampton, Christopher, Merry, Sally“…BACKGROUND: Approximately 10%-12% of New Zealand children and young people have long-term physical conditions (chronic illnesses) and are more likely to develop psychological problems, particularly anxiety and depression. Delayed treatment leads to worse health care and poorer long-term outcomes. …”
Publicado 2021
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