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  1. 488881
    “…BACKGROUND: Acute respiratory tract infection (ARI) is one of the leading causes of illness and mortality in children under the age of five worldwide. …”
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    Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia
  2. 488882
    “…In the clinical environment, AKI is linked to a high rate of death and leads to the progression of AKI to chronic renal disease. …”
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    Potential impact of serpin peptidase inhibitor clade (A) member 4 SERPINA4 (rs2093266) and SERPINA5 (rs1955656) genetic variants on COVID-19 induced acute kidney injury
  3. 488883
    “…Importantly, multiple chronic diseases leading to high morbidity and mortality in modern western societies, including type II diabetes, IBD and colorectal cancer, have epidemiologically been linked to the consumption of high-calorie, low-fiber, high monosaccharide, and high-fat diets (HFD). …”
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    Harnessing the Biology of Canine Intestinal Organoids to Heighten Understanding of Inflammatory Bowel Disease Pathogenesis and Accelerate Drug Discovery: A One Health Approach
  4. 488884
    “…Background Studies suggest that COVID-19 infection may induce increased hypercoagulability, leading to thrombotic complications. The high rates of thrombotic complications among patients receiving standard-dose deep venous thrombosis (DVT) prophylaxis have prompted some clinicians to support the empiric increase of anticoagulation (AC) doses used for prophylaxis in patients with COVID-19. …”
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    Use of Systemic Anticoagulation in COVID-19: Delving Beyond Theoretical Hypothesis
  5. 488885
    por Liu, Bo, Zhao, Binghao, Zhang, Qingsong
    Publicado 2022
    “…CONCLUSION: Direct anterior approach combined with direct posterior approach in Pipkin IV femoral head fractures does not increase operative time and intraoperative estimated blood loss but can lessen severity of pain and promote functional recovery of the hip, leading to a favorable prognosis while not increasing the incidence of complications.…”
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    Efficacy of direct anterior approach combined with direct posterior approach in Pipkin IV femoral head fractures
  6. 488886
    “…BACKGROUND: Myocardial fibrosis caused by myocardial infarction (MI) is the key factor leading to cardiac remodeling; nod-like receptor family pyrin domain-containing 3 (NLRP3) plays an important role in regulation of myocardial injury; however, its relationship with TLR4/MyD88/NF-κB signaling pathway is largely unreported. …”
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    LuQi Formula Ameliorates Myocardial Fibrosis by Suppressing TLR4/MyD88/NF-κB Pathway and NLRP3 Inflammasome Activation in Mice with Myocardial Infarction
  7. 488887
    “…ABSTRACT: Apis cerana is the original host for Nosema ceranae, a widespread fungal parasite resulting in honey bee nosemosis, which leads to severe losses to the apiculture industry throughout the world. …”
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    Comparative Transcriptome Investigation of Nosema ceranae Infecting Eastern Honey Bee Workers
  8. 488888
    “…BACKGROUND: Mental disorders are a leading cause of distress and disability worldwide. …”
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    Telehealth Versus Face-to-face Psychotherapy for Less Common Mental Health Conditions: Systematic Review and Meta-analysis of Randomized Controlled Trials
  9. 488889
    “…However, for patients with head and neck cancer, the response rate to ICI monotherapy remains low, leading to the exploration of combinatorial treatment strategies. …”
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    Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer
  10. 488890
    “…Mechanistically, eEF2K directly bound to and inactivated glycogen synthase kinase 3 beta (GSK3β) by phosphorylating it at serine 9 (S9), leading to PD-L1 protein stabilization and upregulation, and subsequently tumor immune evasion. …”
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    eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma
  11. 488891
    “…We aim to examine, whether adjusting the triage category by age leads to improvement in sensitivity without excessive increase in patient numbers in the higher triage categories. …”
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    Effect of age adjustment on two triage methods
  12. 488892
    “…Among these organs, heart showed highest ·OH level due to the high distribution of ultrasmall Fe(3)O(4) nanoparticles, leading to the acute cardiac failure and death. CONCLUSION: Ultrasmall Fe(3)O(4) nanoparticles (2.3 and 4.2 nm) showed high toxicity in vivo due to the distinctive capability in inducing the generation of ·OH in multiple organs, especially in heart. …”
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    Ultrasmall iron oxide nanoparticles cause significant toxicity by specifically inducing acute oxidative stress to multiple organs
  13. 488893
    “…BACKGROUND: Open defecation facilitates the transmission of pathogens that cause diarrheal diseases, which is the second leading contributor to the global burden of disease. …”
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    Open defecation practice and its determinants among households in sub-Saharan Africa: pooled prevalence and multilevel analysis of 33 sub-Saharan Africa countries demographic and health survey
  14. 488894
    “…BACKGROUND: Acute otitis media (AOM) is a leading cause of office visits and antibiotic prescriptions in children. …”
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    Incidence of acute otitis media in children in the United States before and after the introduction of 7- and 13-valent pneumococcal conjugate vaccines during 1998–2018
  15. 488895
    “…CONCLUSIONS: Our model identifies new dynamics of critical components in the Ca(2+)/CaM-Src signaling pathway leading to neuronal injury and provides a feasible framework for drug efficacy studies in translational models of neonatal brain injury for the prevention of intellectual and developmental disabilities. …”
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    Computational analysis of cortical neuronal excitotoxicity in a large animal model of neonatal brain injury
  16. 488896
    “…Strictly applying ICHD-3 criteria leads to 8/98 migraine without aura and 0/35 CH classifications. …”
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    mBrain: towards the continuous follow-up and headache classification of primary headache disorder patients
  17. 488897
    “…BACKGROUND: Physical activity (PA) decreased during the COVID-19 pandemic, especially among older adults, potentially leading to adverse consequences for their health. …”
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    Factors associated with physical activity reduction in Swedish older adults during the first COVID-19 outbreak: a longitudinal population-based study
  18. 488898
    “…INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, corresponding to 5% of all deaths globally, with more than 90% occurring in low- and middle-income countries (LMIC). …”
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    Developing Appropriate Pulmonary Rehabilitation Services in Sri Lanka: Assessment of People Living with COPD and Healthcare Providers in Urban and Semi Urban Areas in Sri Lanka
  19. 488899
    “…BACKGROUND: Duchenne muscular dystrophy (DMD) is caused by DMD mutations leading to dystrophin loss. Full‐length Dp427 is the primary dystrophin isoform expressed in muscle and is also expressed in the central nervous system (CNS). …”
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    Investigating the role of dystrophin isoform deficiency in motor function in Duchenne muscular dystrophy
  20. 488900
    “…Smoking is a leading cause of chronic obstructive pulmonary disease (COPD). …”
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    High miR203a-3p and miR-375 expression in the airways of smokers with and without COPD
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