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  1. 488961
    “…German-speaking smartphone users aged ≥18 years living in Switzerland and using at least one of the two leading Swiss grocery loyalty cards, were recruited for the trial. …”
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    The Effect of a Future-Self Avatar Mobile Health Intervention (FutureMe) on Physical Activity and Food Purchases: Randomized Controlled Trial
  2. 488962
    “…Although the current cure rate in pediatric B cell acute leukemia is approximately 90%, it remains one of the leading causes of mortality in childhood. Furthermore, in the contemporary protocols, chemotherapy intensity was raised to the maximal levels of tolerability, and further improvements in the outcome will depend on the characterization and reclassification of the disease, as well as on the development of new targeted drugs. …”
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    Conjoined Genes as Common Events in Childhood Acute Lymphoblastic Leukemia
  3. 488963
    “…BACKGROUND: The underuse or overuse of knowledge products leads to waste in health care, and primary care is no exception. …”
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    Implementation Strategies for Knowledge Products in Primary Health Care: Systematic Review of Systematic Reviews
  4. 488964
    por Wimalawansa, Sunil J.
    Publicado 2022
    “…Considering both D(3) and 25(OH)D enter immune cells for generating calcitriol, using the combination of D(3) (medium-term) and calcifediol (immediate) is cost-effective and leads to the best clinical outcome. To maximise protection against infections, particularly to reduce COVID-19-associated complications and deaths, healthcare workers should advise patients on safe sun exposure, adequate vitamin D supplementation and balanced diets containing zinc, magnesium, and other micronutrients to support the immune system. …”
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    Rapidly Increasing Serum 25(OH)D Boosts the Immune System, against Infections—Sepsis and COVID-19
  5. 488965
    “…Patients with poorly controlled diabetes show a significant alteration in various parameters including metabolic, cellular, immunological, and hematological disturbances that leads to vascular complications. Thus, the main aim of this study is to compare hematological parameters between type 2 diabetes mellitus (T2DM) patients and healthy controls. …”
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    Comparison of hematological parameters between type 2 diabetes mellitus patients and healthy controls at Dessie comprehensive specialized hospital, Northeast Ethiopia: Comparative cross-sectional study
  6. 488966
    “…Furthermore, we identified a novel mechanism: DNMT1 directly bound to EZH2 and recruited EZH2 and HDAC2 complexes to the promoter region of miR-148a, leading to miR-148a downregulation. In breast cancer tissues, HDAC2 and EZH2 protein expression levels also were inversely correlated with levels of miR-148a expression. …”
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    HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance
  7. 488967
    “…Greater awareness of the potential risks of SARS-CoV-2 transmission between secondary school students potentially leading to increased risk of infection in their teachers and their household members may increase adherence to infection control measures within and outside schools. …”
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    Perceptions of adolescents on the COVID-19 pandemic and returning to school: qualitative questionnaire survey, September 2020, England
  8. 488968
    “…We found little evidence that providing patients with initial assistance in registering for or accessing web-based services leads to increased long-term use. Few studies have addressed the effects of digital facilitation on health care inequalities. …”
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    Digital Facilitation to Support Patient Access to Web-Based Primary Care Services: Scoping Literature Review
  9. 488969
    “…An increased level of engagement leads to better weight losses.…”
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    Weight loss outcomes achieved by adults accessing an online programme offered as part of Public Health England’s ‘Better Health’ campaign
  10. 488970
    “…BACKGROUND: Osteoarthritis (OA) pain is common and leads to functional impairment for many older adults. …”
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    Linking physical activity to personal values: feasibility and acceptability randomized pilot of a behavioral intervention for older adults with osteoarthritis pain
  11. 488971
    por Işın, Ali, Peden, Amy E.
    Publicado 2022
    “…INTRODUCTION: Drowning is an under-recognised public health threat and a leading cause of injury-related mortality and morbidity. …”
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    Assessing variations in estimates of drowning mortality in Turkey from 2013 to 2019
  12. 488972
    “…Postoperative patient-reported outcomes were compared between failure and non-failure cohorts in the timepoints leading up to the mean decision time to validate that failure correlated with worse PROMs. …”
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    Poster 212: The Cartilage Early Return for Transplant (CERT) Score: Predicting Early Patient Election to Proceed with Cartilage Transplant Following Chondroplasty of the Knee
  13. 488973
    “…IMPORTANCE: Alcohol consumption (AC) leads to death and disability worldwide. Ongoing discussions on potential negative effects of the COVID-19 pandemic on AC need to be informed by real-world evidence. …”
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    Patterns of Alcohol Consumption Among Individuals With Alcohol Use Disorder During the COVID-19 Pandemic and Lockdowns in Germany
  14. 488974
    “…Use of the global demethylating agent 5-aza-2’-deoxycytidine decreases methylation leading to increased LRIG1 transcript expression in basal/triple-negative cell lines, while having no effect on LRIG1 expression in luminal/ER-positive cell lines. …”
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    Aberrant promoter methylation contributes to LRIG1 silencing in basal/triple-negative breast cancer
  15. 488975
    “…Bacteria, despite having the natural ability to consume xylose are unable to consume it in presence of glucose due to a carbon catabolite repression (CCR) mechanism. This leads to overall reduced productivity as well as incomplete xylose utilization due to ethanol build-up from glucose utilization. …”
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    Adaptation on xylose improves glucose–xylose co-utilization and ethanol production in a carbon catabolite repression (CCR) compromised ethanologenic strain
  16. 488976
    “…Sepsis serves as a leading cause of admission to and death of patients in the intensive care unit (ICU) and is described as a systemic inflammatory response syndrome caused by abnormal host response to infection. …”
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    Adipose-derived mesenchymal stem cell-derived HCAR1 regulates immune response in the attenuation of sepsis
  17. 488977
    “…Aspergillus flavus infects various crops with aflatoxins, and leads to aspergillosis opportunistically. Though H3K36 methylation plays an important role in fungal toxin metabolism and virulence, no data about the biological function of H3K36 methylation in A. flavus virulence has been reported. …”
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    Set2 family regulates mycotoxin metabolism and virulence via H3K36 methylation in pathogenic fungus Aspergillus flavus
  18. 488978
    “…CONCLUSION: Persistent headache attributed to ischemic stroke is not rare and frequently leads to medication overuse. The problem is often neglected because of other serious consequences of stroke but actually, it has a considerable impact on quality of life. …”
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    Persistent headache after first-ever ischemic stroke: clinical characteristics and factors associated with its development
  19. 488979
    por Mo, Kevin, Musharbash, Farah, Jain, Amit
    Publicado 2022
    “…The amount of ED spine fractures leading to admission decreased (14.69% DC vs 25% BC) while the amount released increased (61% vs. 55%) (p < 0.001). …”
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    P54. Emergency department visits for pediatric spine fractures: trends through COVID-19
  20. 488980
    “…BACKGROUND: The chronic pain of patients with knee osteoarthritis (KOA) seriously affects their quality of life and leads to heavy social and economic burden. As a nondrug therapy in Traditional Chinese Medicine (TCM), Tuina is generally recognised as safe and effective for reducing the chronic pain of KOA. …”
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    Cerebral mechanism of Tuina analgesia in management of knee osteoarthritis using multimodal MRI: study protocol for a randomised controlled trial
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