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  1. 488981
    “…RESULTS: We present the first report of a patient with a heterozygous de novo missense mutation c.C1123 > G;p.L375V in CYP4F3 that severely impairs its activity by 50% (P < 0.0001), leading to reduced metabolization of the pro‐inflammatory LTB4. …”
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    A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer
  2. 488982
    “…Although studies report efficacy, a key concern regarding web-based interventions is the lack of engagement leading to drop out, lack of participation, or reduced potential intervention benefits. …”
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    Understanding Engagement in Digital Mental Health and Well-being Programs for Women in the Perinatal Period: Systematic Review Without Meta-analysis
  3. 488983
    “…The pattern of pathology accompanying COVID-19 has affected hospital policies and direct patient management, leading to a paradigm shift in approaches, policies, and resource utilization. …”
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    Antibiogram at a Rural Hospital Against the Background of COVID-19: A Five-Year Retrospective Review
  4. 488984
    “…However, some issues need to be addressed for the application of COFs in the extraction of toxic and hazardous substances. (1) For the sample matrix, most of the reported COFs are highly hydrophobic, which limits their dispersibility in water-based samples, leading to poor extraction performance. COFs with good dispersibility in water-based samples are urgently required. (2) Besides, COFs rely on hydrophobic interaction, size repulsion, π-π stacking, and Van der Waals forces to extract target substances, but they are not effective for some polar targets. …”
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    共价有机骨架材料在有毒有害物质萃取中的应用进展
  5. 488985
    “…In addition, the presence of the multi-glycan structure of ginsenoside leads to higher binding affinity between the PEI-BA-MNPs due to the synergistic multivalent binding effect. …”
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    支链聚乙烯亚胺辅助硼酸功能化磁性纳米粒子的制备及其用于人参皂苷的特异性富集
  6. 488986
    por WEN, Hanrong, ZHU, Jue, ZHANG, Bo
    Publicado 2021
    “…When liquid chromatography is coupled with mass spectroscopy, a low flow rate can increase the ionization efficiency, leading to enhanced sensitivity of the mass spectrometer. …”
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    芯片液相色谱技术进展
  7. 488987
    “…Meanwhile, some protein bands (which may belong to exosomes) that did not appear in the serum samples appeared in the serum exosome samples, leading to the conduciveness of subsequent mass spectrometry analysis. …”
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    血清和血清外泌体的蛋白质组分析及其在肝内胆管癌中的应用
  8. 488988
    por Tang, Zeyu, Jia, Jinzhu
    Publicado 2022
    “…Background: Preterm birth (PTB) leads to short-term and long-term adverse effects on newborns. …”
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    The Association between the Burden of PM(2.5)-Related Neonatal Preterm Birth and Socio-Demographic Index from 1990 to 2019: A Global Burden Study
  9. 488989
    “…BACKGROUND: Tobacco smoking is a leading cause of premature death in China, especially among adult men. …”
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    Trends in smoking prevalence in urban and rural China, 2007 to 2018: Findings from 5 consecutive nationally representative cross-sectional surveys
  10. 488990
    “…T-cell recognition of antigen is the primary and central event that leads to the cascade of events that result in rejection of a transplanted organ. …”
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    Solid Organ Rejection following SARS-CoV-2 Vaccination or COVID-19 Infection: A Systematic Review and Meta-Analysis
  11. 488991
    “…CONCLUSION: lnc-HOXB8-1:2 in exosomes derived from neuroendocrine differentiated CRC cells acted as a ceRNA competitively binding hsa-miR-6825-5p to upregulate CXCR3 expression and leading to TAM infiltration and M2 polarization, which promotes neuroendocrine differentiated CRC progression. …”
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    Exosome-derived lnc-HOXB8-1:2 induces tumor-associated macrophage infiltration to promote neuroendocrine differentiated colorectal cancer progression by sponging hsa-miR-6825-5p
  12. 488992
    “…Our primary hypothesis is that the pre- and postoperative adjuvant use of the eHealth application “alley” (intervention group, IG) leads to improved functional outcome. METHODS: Prospective, randomized, controlled, multi-center trial including n = 200 patients diagnosed with hip and n = 200 patients with knee OA (n = 200) scheduled for TJA. …”
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    Evaluation of the patient-accompanying app “alley ortho companion” for patients with osteoarthritis of the knee and hip: study protocol for a randomized controlled multi-center trial
  13. 488993
    “…BACKGROUND: Chronic disease is the leading cause of premature death globally, and many of these deaths are preventable by modifying some key behavioural and metabolic risk factors. …”
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    Changes in health behaviours in adults at-risk of chronic disease: primary outcomes from the My health for life program
  14. 488994
    “…We hypothesized that lockdown precipitated increased prevalence of insomnia symptoms relative to the pre-pandemic period; b) the gradual relaxation of containment measures – post-lockdown period (Phase 2 and Phase 3) – reduced insomnia severity, leading to a relative recovery of pre-pandemic levels; and c) we tested age-related heterogeneity in sleep responses, with an expected higher increase in insomnia in younger and middle-age groups. …”
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    The prevalence of insomnia in different COVID-19 policy phases: Longitudinal evidence from ITA.LI – Italian Lives
  15. 488995
    “…BACKGROUND: Type 2 Diabetes Miletus (T2DM) is a public health burdens that alarmingly increases and leads to morbidity and mortality over the last decades globally. …”
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    Non-adherence to medication and associated factors among type 2 diabetes patients at Clinique Medicale Fraternite, Rwanda: a cross-sectional study
  16. 488996
    “…Lack of marital intimacy leads to unfortunate consequences such as dissatisfaction with marital relationships between spouses. …”
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    Investigating the effect of couple-centered counseling by Gottman method on the intimacy of infertile couples referring to the infertility Ward of Fatemieh hospital, Hamadan, Iran in 2020: a quasi-experimental study
  17. 488997
    “…The Th17 increase is dependent on extracellular bacteria, and increased bacteria leads to lower Th2-type generation. Secreted group IIA-phospholipase A2 (sPLA2-IIA) from the Pla2g2a gene can bind to gram-positive bacteria and degrade bacterial membranes, controlling microbiota in the intestine. …”
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    Pla2g2a promotes innate Th2-type immunity lymphocytes to increase B1a cells
  18. 488998
    “…Severe anxiety and noncompliance ahead of frequent invasive therapies leads to an increase in health care costs. Previous studies have shown that therapeutic video games (TVGs) can decrease the anxiety experienced by children who are ill. …”
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    Development of a Therapeutic Video Game With the MDA Framework to Decrease Anxiety in Preschool-Aged Children With Acute Lymphoblastic Leukemia: Mixed Methods Approach
  19. 488999
    “…However, the production of Mali Ong has fluctuated substantially in recent years, leading to shortages. Consequently, farmers have turned to using other Kluai Namwa varieties including Nuanchan. …”
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    Nutraceutical Difference between Two Popular Thai Namwa Cultivars Used for Sun Dried Banana Products
  20. 489000
    “…BACKGROUND: Heart failure (HF) is a prevalent chronic disease and is associated with increases in mortality and morbidity. HF is a leading cause of hospitalizations and readmissions in the United States. …”
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    Continuous Remote Patient Monitoring in Patients With Heart Failure (Cascade Study): Protocol for a Mixed Methods Feasibility Study
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