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  1. 489041
    “…However, we suspected that she had calcium malabosoprtion in light of hypochlorhydria and hypergastrinemia, both leading to hyperPTH. Subsequently, she was started on oral calcium citrate 1200mg daily as the absorption of calcium citrate is non PH dependent. …”
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    PSAT227 Clinically Suspected Calcium Malabsorption and Secondary Hyperparathyroidism Due to Chronic Proton Pump Inhibitor Use in a Child
  2. 489042
    “…Our initial characterization supports the notion that CCN5 promotes the proliferation and survival of pancreatic β-cells leading to metabolic benefits [1]. Recently, the effects of CCN5 gene deficiency and ectopic, transgenic overexpression of CCN5 have been established. …”
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    PSUN136 CCN5/WISP2 gene deficiency improves insulin sensitivity and glucose tolerance in diet-induced obesity, especially in male mice
  3. 489043
    “…INTRODUCTION: Osteoporosis is characterized by weakening of the bone, disruption of its architecture, and loss of skeletal strength, leading to increased risk of fragility fractures. …”
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    RF06 | PSAT155 Are We Following the Recommendations to Screen for and Treat the "Silent Killer" in Our Geriatric Population? A Quality Improvement Project
  4. 489044
    “…Treatment with glucocorticoids inhibits calcitriol synthesis leading to quick resolution of hypercalcemia. While use of glucocorticoids are commonplace in the management of granulomatous disease due to sarcoidosis, they have been increasingly recognized as an important risk factor for melioidosis, considered to result from suppression of innate immunity. …”
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    ODP110 Parathyroid Hormone Independent Hypercalcaemia Secondary to Granulomatous Inflammation: Could This Be Melioidosis?
  5. 489045
    “…INTRODUCTION: Hypertriglyceridemia is the third most common cause of acute pancreatitis, leading to increased morbidity and mortality. Hypocalcemia is a frequent complication of pancreatitis, attributed to saponification of calcium by the release of pancreatic lipase. …”
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    RF32 | PSUN67 Recurrent Acute Pancreatitis Secondary to Hypertriglyceridemia in an Adolescent With Type 2 Diabetes, Symptomatic Hypocalcemia, and COVID-19 Infection
  6. 489046
    “…Most cases are due to systemic parathyroid hormone-related protein, followed by osteolytic metastases leading to inflammatory cytokines locally released and least common via ectopic production of 1,25 dihydroxy vitamin D. …”
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    PSAT190 Denosumab use for life-threatening hypercalcemia of malignancy in a toddler. A weight base dose
  7. 489047
    “…Misdiagnosis of MODY as type 1 diabetes (T1DM) or young-onset type 2 diabetes (T2DM) due to their overlapping features is common, leading to suboptimal pharmacologic management. When pharmacologic therapy is indicated, patients with MODY-3 typically present an excellent response to sulfonylurea monotherapy. …”
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    PSUN269 Suboptimal Sulfonylurea Therapeutic Response in a Patient with MODY-3 with a Rare HNF1A Pathogenic Genetic Variant
  8. 489048
    “…Cardiovascular disease (CVD) is the leading killer of women at all ages and CVD mortality rates are unchanged or increasing in young women aged 35-44 years. …”
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    OR19-6 Functional Hypothalamic Amenorrhea and Preclinical Cardiovascular Disease
  9. 489049
    “…Hypocalcemia in our patient could be multifactorial, however we believe that COVID-19 induced HPT was the leading mechanism. We hope that further research explores this hypothesis and elucidates the underlying pathophysiology. …”
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    ODP100 Hypoparathyroidism in the Setting of COVID-19: Increasingly Common Phenomenon
  10. 489050
    “…CONCLUSION AND SIGNIFICANCE: Together our results show that embryonic glucose exposure leads to increased lipid accumulation which can be rescued by blocking glycolysis or de novo lipogenesis. …”
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    OR24-5 Zebrafish in Utero Glucose Exposure Induces Lipid Dysregulation That Is Abrogated by Acetyl CoA Carboxylase or Glycolysis Inhibition
  11. 489051
    “…BACKGROUND: Pheochromocytoma is a rare neoplasm of the adrenal medulla that leads to catecholamine excess. Adrenalectomy is the standard management for operative candidates. …”
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    PSUN11 Outcomes of Nonselective or Selective Alpha-Adrenergic Antagonist for Preoperative Management of Intra-adrenal Pheochromocytoma
  12. 489052
    “…Briefly, insulin activates insulin receptor (IR) which leads to activation of phospho-AKT which increases phosphorylated forkhead box 01 (p-FOXO1, gluconeogenesis regulation) and transcriptionally regulates acetyl co-A carboxylase (ACC, de novo lipogenesis (DNL) regulation). …”
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    PSUN123 Increased Expression of Insulin Signaling Intermediates After Six-Months Of Medical Care In Women With Obesity And Polycystic Ovary Syndrome
  13. 489053
    “…BACKGROUND: Obesity results from excess adipose triglyceride storage and leads to multiple life-threatening complications that may be amenable to novel pharmacological therapies. …”
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    RF36 | PSUN79 Prolonged Stimulation of β-Adrenergic Receptors in Human Brown and White Adipocytes Increases and then Decreases Metabolic Activity
  14. 489054
    “…BACKGROUND: Cigarette smoking is the leading preventable cause of premature death. Despite dedicated programs, quit rates remain low due to barriers such as nicotine withdrawal syndrome or post-cessation weight gain. …”
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    RF32 | PSUN59 Glucagon-Like Peptide-1 Analogues: A New Way to Quit Smoking? SKIP – a Randomised Controlled Study
  15. 489055
    “…Activation of gonadotropin-releasing hormone receptors (GnRHRs) leads to an increase in intracellular calcium; therefore, this pathway can be used for visualizing the activation of gonadotropes. …”
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    PMON55 Calcium Imaging in the Intact Mouse Pituitary: A Novel Design for Understanding the Formation and Modulation of the Gonadotrope Network
  16. 489056
    “…We wondered if prenatal androgen exposure leads gut microbial dysbiosis early in life and is associated with the development of PCOS in later life. …”
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    RF10 | PMON241 Temporal Changes in Phenotype and Gut microbiota in PCOS Mouse Model Induced by Prenatal Androgen Exposure.
  17. 489057
    “…Abiraterone acetate (AA) is an irreversible inhibitor of the 17α-hydroxylase/C17, 20-lyase (CYP17 enzyme) that is used in patients with prostate cancer, in whom it leads to suppression of cortisol and androgens. Thus, the drug is potentially useful in the medical treatment of steroid-secreting tumors. …”
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    OR12-1 Activity of Abiraterone Acetate in the management of Cushing syndrome associated to advanced adrenocortical carcinoma: results of the ABACUS trial.
  18. 489058
    por Arous, Tania, MacLeod, Sara
    Publicado 2022
    “…Wilson's disease is an autosomal recessive disorder which leads to copper accumulation in the liver and brain, liver transplantation is considered in the presence of acute liver failure. …”
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    PSAT315 Liver Failure and Thyrotoxicosis Triggered by Wilson's Disease
  19. 489059
    “…Fetal loss may result from reduced uteroplacental perfusion and fetal hypokalemia leading to fatal arrhythmia. The most common precipitating factors of DKA in pregnancy are infection, including COVID-19, insulin therapy non-adherence, steroid use, dehydration, and unrecognized new-onset diabetes which accounts for up to 30% of cases. …”
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    PSUN261 Diabetic Ketoacidosis Complicating Gestational Diabetes Mellitus: A Case Report
  20. 489060
    “…Typically airway compromise from large otherwise stable benign goiters results from sudden hemorrhage into a cyst, upper respiratory tract infection leading to tracheal edema, or worseningcomorbid conditions. …”
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    ODP470 Compressive Goiter with COVID-19: An Unusual Etiology of Respiratory Distress Requiring Endotracheal Intubation with Surgical Resection
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