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489541por LaPorte, Ron“…We have published over 68 papers in leading medical journals including the Lancet, British Medical Journal, Nature Medicine among others. …”
Publicado 1999
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489542“…The most negative CCs (%) to the new drug leads were: taxotere-carmustine (BCNU) (-75), taxol-cisplatin (-58), ara-C-taxol (-25), gemcitabin-doxorubicin (-32), camptotecin-VM26 (-41) and topotecan-VP16 (-17). …”
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489543por Herter, C A.“…The withdrawal of carbohydrate food frequently leads to a considerable reduction in the quantity of organic acids excreted. …”
Publicado 1901
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489544por Cotton, Henry A.“…The so called central neuritis assumes a peculiar attitude in that it plainly leads swiftly to an acute fatty degeneration of the ganglion cells, in which there exists an inclination of the fatty granules to flow together into large masses. …”
Publicado 1915
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489545“…Potentials recorded from the cell body of the neurons with intracellular leads gave resting potentials of 70 to 80 mv. and action potentials which in fresh preparations exceeded the resting potentials by about 10 to 20 mv. …”
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489546“…BACKGROUND: Chlamydia trachomatis is a unique obligate intracellular bacterium that remains the leading cause of sexually transmitted bacterial diseases and preventable blindness worldwide. …”
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489547por Amoss, Harold L.“…The introduction of fresh, normal mice into a community in which sporadic deaths are occurring leads regularly, not to the further extension of the sporadic deaths, but to an epidemic spread, as shown by high mortality and high cage attack rate. …”
Publicado 1922
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489548por Lindesmith, Lisa C, Donaldson, Eric F, LoBue, Anna D, Cannon, Jennifer L, Zheng, Du-Ping, Vinje, Jan, Baric, Ralph S“…BACKGROUND: Noroviruses are the leading cause of viral acute gastroenteritis in humans, noted for causing epidemic outbreaks in communities, the military, cruise ships, hospitals, and assisted living communities. …”
Publicado 2008
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489549por Moorsel, C J A van, Pinedo, H M, Veerman, G, Bergman, A M, Kuiper, C M, Vermorken, J B, van der Vijgh, W J F, Peters, G J“…CDDP acts by formation of platinum (Pt)–DNA adducts; dFdC by dFdCTP incorporation into DNA, subsequently leading to inhibition of exonuclease and DNA repair. …”
Publicado 1999
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489550por Dunker, A Keith, Oldfield, Christopher J, Meng, Jingwei, Romero, Pedro, Yang, Jack Y, Chen, Jessica Walton, Vacic, Vladimir, Obradovic, Zoran, Uversky, Vladimir N“…On the other hand, the prediction of intrinsic disorder has been revolutionary, leading to major modifications of the more than 100 year-old views relating protein structure and function. …”
Publicado 2008
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489551por Caulfield, Mark J, Munroe, Patricia B, O'Neill, Deb, Witkowska, Kate, Charchar, Fadi J, Doblado, Manuel, Evans, Sarah, Eyheramendy, Susana, Onipinla, Abiodun, Howard, Philip, Shaw-Hawkins, Sue, Dobson, Richard J, Wallace, Chris, Newhouse, Stephen J, Brown, Morris, Connell, John M, Dominiczak, Anna, Farrall, Martin, Lathrop, G. Mark, Samani, Nilesh J, Kumari, Meena, Marmot, Michael, Brunner, Eric, Chambers, John, Elliott, Paul, Kooner, Jaspal, Laan, Maris, Org, Elin, Veldre, Gudrun, Viigimaa, Margus, Cappuccio, Francesco P, Ji, Chen, Iacone, Roberto, Strazzullo, Pasquale, Moley, Kelle H, Cheeseman, Chris“…In a cohort of men we showed that genetic variants of SLC2A9 are associated with reduced urinary urate clearance, which fits with common variation at SLC2A9 leading to increased serum urate. We found no evidence of association with hypertension (odds ratio 0.98, 95% confidence interval [CI] 0.9 to 1.05, p > 0.33) by meta-analysis of an SLC2A9 variant in six case–control studies including 11,897 participants. …”
Publicado 2008
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489552por Tiewsoh, Karalanglin, Lodha, Rakesh, Pandey, Ravindra M, Broor, Shobha, Kalaivani, M, Kabra, Sushil K“…BACKGROUND: Pneumonia is one of the leading causes of morbidity and mortality in under fives. …”
Publicado 2009
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489553por Tzur, Shay, Rosset, Saharon, Shemer, Revital, Yudkovsky, Guennady, Selig, Sara, Tarekegn, Ayele, Bekele, Endashaw, Bradman, Neil, Wasser, Walter G., Behar, Doron M., Skorecki, Karl“…Accordingly, MYH9 was further explored in these studies as the leading candidate gene responsible for the MALD signal. …”
Publicado 2010
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489554por Nutting, Christopher M, Morden, James P, Harrington, Kevin J, Urbano, Teresa Guerrero, Bhide, Shreerang A, Clark, Catharine, Miles, Elizabeth A, Miah, Aisha B, Newbold, Kate, Tanay, MaryAnne, Adab, Fawzi, Jefferies, Sarah J, Scrase, Christopher, Yap, Beng K, A'Hern, Roger P, Sydenham, Mark A, Emson, Marie, Hall, Emma“…INTERPRETATION: Sparing the parotid glands with IMRT significantly reduces the incidence of xerostomia and leads to recovery of saliva secretion and improvements in associated quality of life, and thus strongly supports a role for IMRT in squamous-cell carcinoma of the head and neck. …”
Publicado 2011
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489555“…Given that molecular volume, a somewhat vague concept, is rather effective, it leads one to wonder: can the existing PubChem 3-D neighboring relationship, which consists of billions of shape similar conformer pairs from tens of millions of unique small molecules, be used to identify additional shape descriptor relationships? …”
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489556“…For the haves, the need is to seek well-being, positive health, and inner rootedness; to ask science not only to give them new pills for new ills, but to define and study how negative emotions hamper health and how positive ones promote it; to find out what is inner peace, what is the connection between spirituality and health, what is well-being, what is self-actualisation, what prevents disease, what leads to longevity, how simplicity impacts health, what attitudes help cope with chronic sicknesses, how sicknesses can be reversed (not just treated), etc. …”
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489557por La, David, Czarnecki, Chris, El-Gabalawy, Hani, Kumar, Anand, Meyers, Adrienne F. A., Bastien, Nathalie, Simonsen, J. Neil, Plummer, Francis A., Luo, Ma“…This suggests a possible association with NK cell dysfunction in patients with overactive immune responses to H1N1/09, leading to severe disease.…”
Publicado 2011
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489558“…This type of large-scale computational scanning could be coupled with proteomic and metabolomic studies of this parasite leading to novel therapeutic intervention and disease control strategies. …”
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489559por Duthoit, Guillaume, Fressart, Véronique, Hidden-Lucet, Françoise, Simon, Françoise, Kattygnarath, Darouna, Charron, Philippe, Himbert, Caroline, Aouate, Philip, Guicheney, Pascale, Lecarpentier, Yves, Frank, Robert, Hébert, Jean-Louis“…For angiographic comparison, 49 patients with localized ARVD/C but without ST segment elevation in the right precordial leads (14 F, 35 M, 39 ± 13 y) were also studied. …”
Publicado 2012
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489560“…INTRODUCTION: Since 2008, poisoning has become the leading cause of injury-related death in the United States (US); since 1980, the poisoning-related fatality rate in the US has almost tripled.1 Many poison-related injuries and deaths are reported to regional poison centers (PCs) which receive about 2.4 million reports of human chemical and poison exposures annually.2 Federal, state, and local public health (PH) agencies often collaborate with poison centers and use PC data for public health surveillance of poisoning-related health issues. …”
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