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  1. 489901
    “…INTRODUCTION: Infections are a leading cause of mortality in patients with systemic lupus erythematosus (SLE). …”
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    Epidemiology and risk of invasive fungal infections in systemic lupus erythematosus: a nationwide population-based cohort study
  2. 489902
    “…BACKGROUND: Chronic chagasic cardiomyopathy (CCC) is the leading cause of heart failure in Latin America and often causes severe inflammation and fibrosis in the heart. …”
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    Comprehensive analysis of miRNA–mRNA regulatory network and potential drugs in chronic chagasic cardiomyopathy across human and mouse
  3. 489903
    “…BACKGROUND: Ovarian cancer is the leading cause of death in patients with gynecologic cancer, and circular RNAs (circRNAs) are involved in cancer progression. …”
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    CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis
  4. 489904
    “…RESULTS: Of 317 individuals with LS, 86 (27%) underwent a total of 105 SIC surveillance examinations, with 5 leading to additional work-up and no SICs diagnosed. …”
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    Uptake and outcomes of small intestinal and urinary tract cancer surveillance in Lynch syndrome
  5. 489905
    “…BACKGROUND: Anemia is one of the world’s leading cause of disability and the most serious global public health issues. …”
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    Prevalence and determinants of Anemia among pregnant women in sub-Saharan Africa: a systematic review and Meta-analysis
  6. 489906
    “…Across all participants, the leading functional priorities for an ideal transfemoral prosthesis were overall stability, adaptability to variable walking velocity, and lifestyle-related functionality, while the highest-prioritized general characteristics were reliability, comfort, and weight, with highly variable prioritization of cost according to reimbursement status. …”
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    Survey of transfemoral amputee experience and priorities for the user-centered design of powered robotic transfemoral prostheses
  7. 489907
    “…BACKGROUND: Severe coronavirus disease 2019 (COVID-19) often results from the immune-mediated cytokine storm, triggered by granulocyte macrophage-colony stimulating factor (GM-CSF), potentially leading to respiratory failure and death. Lenzilumab, a novel anti-human GM-CSF monoclonal antibody, neutralizes GM-CSF and demonstrated potential to improve clinical outcomes in a matched case-cohort study of patients with severe COVID-19 pneumonia. …”
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    40. Lenzilumab Efficacy and Safety in Newly Hospitalized COVID-19 Subjects: Results From a Phase 3 Randomized Double-Blind Placebo-Controlled Trial
  8. 489908
    “…BACKGROUND: Community acquired pneumonia (CAP) is a leading cause of mortality in children < 5 years, but our understanding of disease pathogenesis remains limited. …”
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    999. Nasal Mucosal Cytokines: Potential Biomarkers for Pediatric Pneumonia Severity and Etiology
  9. 489909
    “…BACKGROUND: In Mexico, Hepatitis A virus (HAV) infection is the leading cause of viral hepatitis in children, yet the pediatric HAV vaccine is not included in the national immunization program (NIP). …”
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    915. Hepatitis A Burden of Disease and Associated Complications in Children and Adults in Mexico: A Retrospective Database Study from 2000-2019
  10. 489910
    “…There were no immediate adverse events (AEs), no AEs leading to study discontinuation, and no vaccine-related serious adverse events reported in the study. …”
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    04. Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) Administered in Meningococcal Vaccine-Naive Participants Across a Broad Age Range (2-55 Years) in Japan
  11. 489911
    “…Future studies will need to examine whether modifying message characteristics can optimize engagement and whether this leads to behavior change.…”
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    Text Message Analysis Using Machine Learning to Assess Predictors of Engagement With Mobile Health Chronic Disease Prevention Programs: Content Analysis
  12. 489912
    “…BACKGROUND: Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a rare disease, which is often underdiagnosed due to its heterogeneous presentations and complex molecular genetic basis, leading to a lack of population-based epidemiology data, especially of prevalence and disease progression. …”
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    Prevalence and disease progression of genetically-confirmed facioscapulohumeral muscular dystrophy type 1 (FSHD1) in China between 2001 and 2020: a nationwide population-based study
  13. 489913
    “…BACKGROUND: Early mobilisation leads to a two-fold increase in the adjusted odds of discharge by 30-days compared to late mobilisation. …”
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    Discharge after hip fracture surgery in relation to mobilisation timing by patient characteristics: linked secondary analysis of the UK National Hip Fracture Database
  14. 489914
    “…End-stage ankle arthritis leads to an elevated joint line compared to non-arthritic ankle. …”
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    The “Joint Line Height Ratio” Assessing the Ankle Joint Line Level Before and After Total Ankle Replacement
  15. 489915
    por Son, Michelle M., Latt, L. Daniel
    Publicado 2019
    “…Compression at the arthrodesis site plays a key role in stimulating bone growth leading to successful fusion. The ability to obtain and maintain compression depends not only on the surgical technique and the hardware which develop the compressive force but also on the response of the bone to compression. …”
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    Hindfoot Bone Viscoelasticity and Stress Relaxation
  16. 489916
    “…Traditionally, yak graze on the rangeland all year round and without any supplementation, and weight loss would occur in the cold season, which leads to rather low productive performance. In recent years, the strategy of intensive feedlot fattening was introduced to the yak raising industry. …”
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    Effect of Supplementary Levels of Rumen-Protected Lysine and Methionine on Growth Performance, Carcass Traits, and Meat Quality in Feedlot Yaks (Bos grunniens)
  17. 489917
    “…In tumor cells with defects in apoptosis, autophagy allows prolonged survival. Autophagy leads to an accumulation of damaged mitochondria by autophagosomes. …”
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    ATPase Activity of the Subcellular Fractions of Colorectal Cancer Samples under the Action of Nicotinic Acid Adenine Dinucleotide Phosphate
  18. 489918
    “…Subsequently, the catalase katE from Mycobacterium neoaurum and an NADH oxidase, nox, from Bacillus subtilis were overexpressed to improve the intracellular environment, leading to a higher 9-OH-4-HP production. Ultimately, 9-OH-4-HP production reached 3.58 g L(−1) from 5 g L(−1) phytosterols, and the purity of 9-OH-4-HP improved to 97%. …”
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    Production of 9,21-dihydroxy-20-methyl-pregna-4-en-3-one from phytosterols in Mycobacterium neoaurum by modifying multiple genes and improving the intracellular environment
  19. 489919
    “…In 2019, suicide was the 10th leading cause of death among persons aged ≥18 years (adults); in that year, 45,861 adults died as a result of suicide, and an estimated 381,295 adults visited hospital emergency departments for nonfatal, self-inflicted injuries. …”
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    Suicidal Thoughts and Behaviors Among Adults Aged ≥18 Years — United States, 2015–2019
  20. 489920
    “…Previous studies showed that inactivated monovalent EV-A71 vaccines were highly efficient against HFMD associated with EV-A71 but not against HFMD with other etiologies, leading to a hypothesis that the introduction of EV-A71 vaccines might change the pathogen spectrum and epidemiological trend of HFMD. …”
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    Changing epidemiology of hand, foot, and mouth disease in China, 2013−2019: a population-based study
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