Mostrando 489,961 - 489,980 Resultados de 490,605 Para Buscar '"lead"', tiempo de consulta: 3.06s Limitar resultados
  1. 489961
    por Nulty, Adam
    Publicado 2022
    “…The evolution of 3D printers that leads to budget printers being as statistically accurate, for at least two of the dimensions of data recorded, as expensive printers is remarkable. …”
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  2. 489962
  3. 489963
    “…BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of severe vision loss in patients over 55 years old in the industrialized world. …”
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  4. 489964
    “…In addition to these searches, leading researchers were contacted to try and identify unpublished or unidentified research. …”
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  5. 489965
  6. 489966
    “…The endpoint was conception leading to ongoing pregnancy, defined as a foetus reaching a gestational age of at least 12 weeks. …”
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  7. 489967
    “…BACKGROUND: Chronic obstructive pulmonary disease (COPD) is one of the world’s leading causes of death and a major chronic disease, highly prevalent in the aging population exposed to tobacco smoke and airborne pollutants, which calls for early and useful biomolecular predictors. …”
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  8. 489968
    “…Loss of transporter function leads to intralysosomal cystine accumulation and long-term damage to various tissues and organs, including the kidneys, eyes, liver, muscles, pancreas, and brain. …”
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  9. 489969
  10. 489970
  11. 489971
    “…METHODS: In this retrospective population analysis, we assessed vaccine effectiveness against SARS-CoV-2 infection and severe COVID-19, defined as an infection leading to hospitalisation or death, by linking the national COVID-19 surveillance system and the national vaccination registry. …”
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  12. 489972
    “…BACKGROUND/AIM: Prostate-specific-membrane-antigen/positron emission tomography (PSMA-PET) detects with high accuracy disease-recurrence, leading to changes in the management of biochemically-recurrent (BCR) prostate cancer (PCa). …”
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  13. 489973
  14. 489974
    “…The adjustment process allowed amisulpride to remain cationic, thus leading to improved transfer and trapping efficiencies in strong cation-exchange columns, in the heart-cutting mode. …”
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  15. 489975
    “…However, dysregulation of phosphorylated proteins usually leads to a disorder in the intracellular signaling pathways and the onset of various diseases, especially cancer. …”
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  16. 489976
    “…The extraction results of RNA from SARS-CoV-2 patient’s sample indicated that the GNPs have an outstanding property over the current existing extraction protocols. It leads to the new advancements in extraction and detection of RNA. …”
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  17. 489977
    “…The most commonly used neurostimulants included amantadine (51%), modafinil (37%), and methylphenidate (28%). The leading determinants for prognostication included etiology of coma, neurological examination findings, and neuroimaging. …”
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  18. 489978
    “…CONCLUSIONS: Together, our results add therapeutic support that T-type/Ca(V)3.2 in primary sensory pathways contributes to MIA-OA pain pathogenesis and that Ca(V)3.2iPAs are promising analgesic leads that, combined with AAV-targeted delivery in anatomically segmental sensory ganglia, have the potential for further development as a peripheral selective T-type/Ca(V)3.2-targeting strategy in mitigating chronic MIA-OA pain behavior. …”
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  19. 489979
    por Siriborvornratanakul, Thitirat
    Publicado 2022
    “…While it sounds reasonable that we should leave repetitive trial-and-error tasks of designing complex network architectures and tuning a lot of hyperparameters to AutoML, leading research using AutoML is still scarce. Thereby, the overall purpose of this case study is to investigate the gap between current AutoML frameworks and practical machine learning development. …”
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  20. 489980
    “…However, the production of (67)Cu in quantities suitable to conduct clinical trials is more challenging as it leads to the coproduction of other Cu isotopes, in particular (64)Cu. …”
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