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  1. 490201
    “…Drug overdoses were the leading cause of increased mortality in midlife in each population, but mortality also increased for alcohol related conditions, suicides, and organ diseases involving multiple body systems. …”
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    Changes in midlife death rates across racial and ethnic groups in the United States: systematic analysis of vital statistics
  2. 490202
    “…CONCLUSIONS: The findings of this investigation showed that delayed chilling of raw milk leads to several undesirable chemical changes in lipid fraction of milk.…”
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    Impact of immediate and delayed chilling of raw milk on chemical changes in lipid fraction of pasteurized milk
  3. 490203
    “…Efficacy against pulmonary TB disease case definition 1 was 54.0% (90% CI: 13.9, 75.4; P = 0.042); efficacy against other case definitions and a sensitivity analysis are shown in Figure 1. Leading solicited symptoms were pain, fatigue, and headache (Figure 2). …”
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    120. A Randomized Double-blind Trial Assessing the Efficacy of M72/AS01(E) Vaccine Against Pulmonary Tuberculosis Disease in Adults With Latent Mycobacterium tuberculosis Infection
  4. 490204
    “…BACKGROUND: Clostridium difficile infection (CDI), a common cause of antibiotic-associated diarrhea, leads to substantial healthcare burden. In children and young adults, the incidence of CDI is increasing. …”
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    LB12. Safety and Efficacy of Fidaxomicin and Vancomycin in Pediatric Patients with Clostridium difficile Infection: Phase III, Multicenter, Investigator-blind, Randomized, Parallel Group (SUNSHINE) Study
  5. 490205
    “…BACKGROUND: Staphylococcus epidermidis is a leading cause of healthcare-associated bacteremia, but the clinical course of S. epidermidis isolated from blood cultures ranges from contamination to serious deep seated infections. …”
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    1036. Whole Genome Sequencing Analysis of a Large Cohort of Staphylococcus epidermidis Blood Culture Positive Isolates From a Multicenter Clinical Trial
  6. 490206
    “…Improved screening for PTA may be clinically important as it leads to appropriate periods of observation prior to safe discharge. …”
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    Evaluation of a targeted, theory-informed implementation intervention designed to increase uptake of emergency management recommendations regarding adult patients with mild traumatic brain injury: results of the NET cluster randomised trial
  7. 490207
    “…BACKGROUND: Polyomavirus-associated nephropathy is a leading cause of kidney allograft failure. Therapeutic options are limited and prompt reduction of the net state of immunosuppression represents the mainstay of treatment. …”
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    Incidence, risk factors, and outcome of BK polyomavirus infection after kidney transplantation
  8. 490208
    “…As a potential therapy, miR-200c can impacts lives as target lung cancer is a leading cause of death with about 234,000 cases annually, high heterogeneity, complex screening, and a 5-year survival rate of 16% [CA Cancer J Clin, 2016.66(1): p. 7-30]. …”
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    Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells
  9. 490209
    “…We hypothesize that young adult 1WR1 rats will have increased glucose intolerance due to the poor regulation of insulin secretion which over time leads to reduced insulin sensitivity and increased adiposity. …”
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    SAT-LB032 Young Adult LEW.1WR1 Rats Develop Increased Glucose Intolerance on a Moderately Increased Sucrose Diet
  10. 490210
    “…Results were inconsistent in COPD patients (I(2) = 66%, p = 0.03), leading to a conflicting level of evidence despite a significant improvement with a large effect size (SMD = 0.92; 95% CI: 0.32, 1.51) after WBV treatment. …”
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    Long-Term Effects of Whole-Body Vibration on Human Gait: A Systematic Review and Meta-Analysis
  11. 490211
    por Waterson, James, Bedner, Arkadiusz
    Publicado 2019
    “…BACKGROUND: Alarm fatigue commonly leads to a reduced response to alarms. Appropriate and timely response to intravenous pump alarms is crucial to infusion continuity. …”
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    Types and Frequency of Infusion Pump Alarms and Infusion-Interruption to Infusion-Recovery Times for Critical Short Half-Life Infusions: Retrospective Data Analysis
  12. 490212
    “…However, the extensive use of antibiotics as growth promoters for a long time leads to the development of antibiotic-resistant bacteria and the possibility of antibiotic-resistant genes being transferred among organisms. …”
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    Effects of Feeding Different Postbiotics Produced by Lactobacillus plantarum on Growth Performance, Carcass Yield, Intestinal Morphology, Gut Microbiota Composition, Immune Status, and Growth Gene Expression in Broilers under Heat Stress
  13. 490213
    “…BACKGROUND: Tuberculosis is a leading cause of morbidity and mortality in humans worldwide. …”
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    Calcitriol enhances pyrazinamide treatment of murine tuberculosis
  14. 490214
    “…Combining NP and AF repairs leads to significantly improved outcomes following disc injury, which warrants the translation of combined repairs into the clinic to improve patient outcomes with degenerative disc disease involving NP and AF.…”
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    3013 Combined Annulus Fibrosus and Nucleus Pulposus Repair Prevents Degeneration in the Ovine Lumbar Spine
  15. 490215
    “…The absence of the sub-pulmonary ventricle leads to abnormal hemodynamics associated with life-threatening complications. …”
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    3212 Development of a Contractile Fontan Circuit to Decrease Central Venous Pressures in Single Ventricle Patients
  16. 490216
    “…DISCUSSION/SIGNIFICANCE OF IMPACT: OS is the most common primary bone tumor and the third leading cause of pediatric cancer deaths. At diagnosis 80% of patients will present with metastasis, however only 20% of these cases are clinically detectable. …”
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    2090 TL1 team approach to osteosarcoma cell detection
  17. 490217
    “…Since the implementation of standardized job classifications and competency-based tier advancement, the positions have undergone rigorous competency-based needs evaluation. This leads to better matched jobs to study needs as well as increased standardization across the clinical research workforce. …”
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    3194 Workforce Engagement and Resilience (WE-R): A Framework for Innovating Clinical Research Careers
  18. 490218
    “…The P.a. strains initially infecting the CF lung have a nonmucoid colony morphology, whereas, once chronic infection is established, these bacteria mutate leading to the emergence of mucoid P.a. variants with heightened resistance to both antibiotics and host immunity. …”
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    2301 Mucoidal pseudomonas aeruginosa infection is associated with regional inflammation in the cystic fibrosis lung
  19. 490219
    “…BACKGROUND: Clostridium difficile infection (CDI) is a leading cause of morbidity and mortality in a hospitalized patient. …”
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    2671. Outcomes of Clostridium difficile Infection in Solid-Organ Transplant Patients: Nationwide Inpatient Sample 2015–2016
  20. 490220
    “…BACKGROUND: Colorectal cancer (CRC) is the second leading cause of all cancer related deaths in the United States and Europe. …”
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    Old vs new: Risk factors predicting early onset colorectal cancer
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