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  1. 490221
    “…BACKGROUND: Enterotoxigenic Escherichia coli causes diarrhoea, leading to substantial mortality and morbidity in children, but no specific vaccine exists. …”
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    Safety and immunogenicity of the oral, inactivated, enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi children and infants: a double-blind, randomised, placebo-controlled phase 1/2 trial
  2. 490222
    “…BACKGROUND: Back pain and neck pain are leading causes of the burden of disease worldwide, while information about their prevalence in Russia is missing. …”
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    Prevalence of and factors associated with low Back pain, thoracic spine pain and neck pain in Bashkortostan, Russia: the Ural Eye and Medical Study
  3. 490223
    “…BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death in women worldwide. The cardiovascular risk profile deteriorates after women enter menopause. …”
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    The cardiovascular risk profile of middle age women previously diagnosed with premature ovarian insufficiency: A case-control study
  4. 490224
    “…Digital images of the cervix have been acquired during VIA procedure with better quality assurance and visualization, leading to higher diagnostic accuracy and reduction of the variability of detection rate. …”
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    Quantitative Screening of Cervical Cancers for Low-Resource Settings: Pilot Study of Smartphone-Based Endoscopic Visual Inspection After Acetic Acid Using Machine Learning Techniques
  5. 490225
    “…Ethics Approval/Approval of the Ethics Committee: Approved. (leading) Ethics Committee Nr.: 18–8316-MF, Ethik-Kommission der Medizinischen. …”
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    Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma: Dosimetric consequences on non-coplanar IMRT as initial results from a phase I trial
  6. 490226
    “…In summary, the results of this study support the role of NAC as an anti-glutamatergic agent, which seems to modulate Glu levels by increasing the availability of intracellular Cys that then combines with Glu to initiate GSH synthesis, leading to a lowering of total Glu levels as measured with MRS…”
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    T165. ANTI-GLUTAMATERGIC PROPERTY OF N-ACETYLCYSTEINE DOCUMENTED IN VIVO WITH 1H MRS
  7. 490227
    “…This corresponds to a 3-fold increase from 113,631 deaths (6,915,170 DALYs) in 1990. The five leading countries with the proportion of deaths attributable to HIV/AIDS in 2017 were Botswana at the top with 28.7% (95% UI; 23.7–35.2), followed by South Africa 28.5% (25.8–31.6), Lesotho, 25.1% (21.2–30.4), eSwatini 24.8% (21.3–28.6), and Mozambique 24.2% (20.6–29.3). …”
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    Burden and changes in HIV/AIDS morbidity and mortality in Southern Africa Development Community Countries, 1990–2017
  8. 490228
    “…Compared with sequence of P. o. wallikeri, the double nonsynonymous mutations of G > A and A > T at the sites of c.1186 and c.1428 leads to the variations of D396N and T476S for the 396th and 476th amino acids positions. …”
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    Polymorphism analysis of propeller domain of k13 gene in Plasmodium ovale curtisi and Plasmodium ovale wallikeri isolates original infection from Myanmar and Africa in Yunnan Province, China
  9. 490229
    por Siemieniuk, Reed AC, Bartoszko, Jessica J, Zeraatkar, Dena, Kum, Elena, Qasim, Anila, Díaz Martinez, Juan Pablo, Izcovich, Ariel, Rochwerg, Bram, Lamontagne, Francois, Han, Mi Ah, Agarwal, Arnav, Agoritsas, Thomas, Azab, Maria, Bravo, Gonzalo, Chu, Derek K, Couban, Rachel, Cusano, Ellen, Devji, Tahira, Escamilla, Zaira, Foroutan, Farid, Gao, Ya, Ge, Long, Ghadimi, Maryam, Heels-Ansdell, Diane, Honarmand, Kimia, Hou, Liangying, Ibrahim, Sara, Khamis, Assem, Lam, Bonnie, Mansilla, Cristian, Loeb, Mark, Miroshnychenko, Anna, Marcucci, Maura, McLeod, Shelley L, Motaghi, Sharhzad, Murthy, Srinivas, Mustafa, Reem A, Pardo-Hernandez, Hector, Rada, Gabriel, Rizwan, Yamna, Saadat, Pakeezah, Switzer, Charlotte, Thabane, Lehana, Tomlinson, George, Vandvik, Per O, Vernooij, Robin WM, Viteri-García, Andrés, Wang, Ying, Yao, Liang, Zhao, Yunli, Guyatt, Gordon H, Brignardello-Petersen, Romina
    Publicado 2020
    “…Several drugs may increase the risk of adverse effects leading to drug discontinuation; hydroxychloroquine probably increases the risk of mechanical ventilation (moderate certainty). …”
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    Drug treatments for covid-19: living systematic review and network meta-analysis
  10. 490230
    “…BACKGROUND: Mental ill-health is the leading cause of disability worldwide. Moreover, 75% of mental health conditions emerge between the ages of 12 and 25 years. …”
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    A Novel Multimodal Digital Service (Moderated Online Social Therapy+) for Help-Seeking Young People Experiencing Mental Ill-Health: Pilot Evaluation Within a National Youth E-Mental Health Service
  11. 490231
    “…WHAT IS KNOWN ALREADY: Patient-centeredness of endometriosis care can be evaluated using the validated ECQ. The ECQ leads to an overall PCS and separate PCS for 10 dimensions of endometriosis care. …”
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    A systematic review and secondary analysis of two studies identifying demographic and medical characteristics determining patient-centeredness in endometriosis care as experienced by patients
  12. 490232
    “…The baby corn sown on broad bed and furrow had the tallest plant (149.25 cm), maximum dry matter (64.33 g plant(−1)), highest leaf area index (3.5), maximum cob length (8.10 cm), cob girth (6.13 cm) and cob weight (8.14 g) leading to significantly higher fresh baby corn yield (1.89 t ha(−1)), and net returns (US$ 906.1 ha(−1)) than those of other treatments. …”
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    Impact of land configuration and organic nutrient management on productivity, quality and soil properties under baby corn in Eastern Himalayas
  13. 490233
    “…Future fertility patterns are a key input to estimation of future population size, but they are surrounded by substantial uncertainty and diverging methodologies of estimation and forecasting, leading to important differences in global population projections. …”
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    Fertility, mortality, migration, and population scenarios for 195 countries and territories from 2017 to 2100: a forecasting analysis for the Global Burden of Disease Study
  14. 490234
    “…IMPORTANCE: Breast cancer is the most commonly diagnosed cancer and the leading cause of death in women worldwide. Yet the racial/ethnic disparity in incidences and distributions of breast cancer remains largely unknown. …”
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    Variation in Breast Cancer Subtype Incidence and Distribution by Race/Ethnicity in the United States From 2010 to 2015
  15. 490235
    “…BACKGROUND: Ventilator-associated pneumonia is the most common intensive care unit (ICU)-acquired infection, yet accurate diagnosis remains difficult, leading to overuse of antibiotics. Low concentrations of IL-1β and IL-8 in bronchoalveolar lavage fluid have been validated as effective markers for exclusion of ventilator-associated pneumonia. …”
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    Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation
  16. 490236
    “…In comparison to Juvenile idiopathic arthritis, Blau often leads to a pan rather than anterior segment only uveitis and in a greater proportion of cases. …”
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    EP25 Blau syndrome: a lifetime of sarcoid
  17. 490237
    por Zou, Yun, Vasta, Bhavisha
    Publicado 2020
    “…Findings from a histological case series suggest that SARS-CoV-2 can infect endothelial cells directly, possibly via endothelial ACE2 receptors, leading to inflammation in the endothelium. Another postulated mechanism is that endothelial cell dysfunction and inflammation is caused by the cytokine storm that can be seen in some patients with COVID-19 infection. …”
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    EP14 COVID-19 associated aortitis
  18. 490238
    por Arora, Palak, Croot, Lorraine
    Publicado 2020
    “…It can also become chronic leading to disabling symptoms. The diagnosis should be considered in all patients presenting with early inflammatory arthritis who have travelled to affected areas. …”
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    EP12 Chikungunga arthritis mimicking acute seronegative spondyloarthritis
  19. 490239
    “…Cortex fragmentation disrupts the Hippo pathway, leading to increased expression of downstream growth factors and follicle growth. …”
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    In-vitro fragmentation of ovarian tissue activates primordial follicles through the Hippo pathway
  20. 490240
    “…BACKGROUND: Cardiovascular disease is the leading cause of death in patients with Duchenne muscular dystrophy (DMD)—a fatal X-linked genetic disorder. …”
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    T(1)-Mapping and extracellular volume estimates in pediatric subjects with Duchenne muscular dystrophy and healthy controls at 3T
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