“…However, cases of patellar fracture have been reported, particularly in the smaller anatomy of the pediatric population, leading to further investigations of patella stabilizing structures. …”
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Severe anaemia (haemoglobin < 6 g/dL) is a leading cause of recurrent hospitalisation in African children. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This new tool can help personalize social-communication programs and evaluations of early intervention outcomes, thereby leading to a fuller picture of these young children’s functioning.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Because tissue factor (TF) is the prime initiator of the extrinsic coagulation cascade, and because it is expressed and exposed under inflammatory conditions leading to vascular damage, we tested the hypothesis that higher TF expression is responsible for thrombi formation in the lungs of patients with severe COVID-19. …”
Enlace del recurso
Enlace del recurso

“…The spectrum of clinical features of COVID-19 can vary from asymptomatic infection to severe multiorgan failure leading to death. There is no single biomarker available that can predict the trajectory of the infected patient. …”
Enlace del recurso
Enlace del recurso

“…Background: Novel coronavirus infection (SARS CoV-2 or COVID-19) is associated with a high risk of thrombotic complications, including macro- and micro-thrombi in major organs, leading to increased morbidity and mortality. Anticoagulant use, mainly heparin, which has both anticoagulant and anti-inflammatory properties, has been suggested as potentially beneficial. …”
Enlace del recurso
Enlace del recurso

“…Life-threatening thrombocytopenia occurred in an auranofin recipient; apparent intra-abdominal sepsis leading to death occurred in another auranofin recipient and was classified as a suspected unexpected serious adverse reaction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Secondary data were collected from the Agency for Healthcare Research and Quality Hospital Compendium, leading to a matched usable dataset of 124 health systems for analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Neonatal disorders remained the leading cause of death in children younger than 5 years in 2019, followed by lower respiratory infections, diarrhoeal diseases, congenital birth defects, and malaria. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This binding induces activation of an intracellular cascade of reactions called signal transduction, which leads to cellular responses. An important example of intracellular signal transduction is JAK/STAT signalling. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cardiovascular diseases (CVD) are the leading cause of excess premature mortality among patients with serious mental illness (SMI), mainly because of higher cardiovascular risk and metabolic syndrome compared to the general population.(1,2) A pertinent contributing factor is second-generation antipsychotics, which further negatively impact the cardiovascular risk burden, amounting to a significant clinical and public health challenge among patients with SMI.(3) Qatar has a high metabolic syndrome prevalence of 26%, and the blood pressure of patients with SMI receiving antipsychotics is significantly higher.(4) In 2019, the Pharmacy Department of Mental Health Services at Hamad Medical Corporation (HMC) in Doha, Qatar flagged four moderately and one mildly severe cases of adverse drug reaction secondary to antipsychotics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…IMPORTANCE: Diabetic retinopathy (DR) is a leading cause of vision loss worldwide. As the incidence of both type 1 and type 2 diabetes among youths continues to increase around the world, understanding the factors associated with the development of DR in this age group is important. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Interruption of therapy leads to negative clinical outcomes and should be avoided, especially in the setting of advanced disease, as the risk of contracting COVID-19 in the outpatient setting did not outweigh the risk of morbidity and mortality due to disease progression. …”
Enlace del recurso
Enlace del recurso

“…Specifically, AgNPs drive cell death through lipid peroxidation leading to proteotoxicity and necrotic cell death, whereas Ag(+) increases H(2)O(2), which drives oxidative stress and apoptotic cell death. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Considering that the clinical symptoms of IFG are inconspicuous, these tend to be easily ignored by individuals, leading to conversion to diabetes mellitus (DM). In this study, we established a prediction model for the onset risk of IFG in the Chongqing health check-up population to provide a reference for prevention in a health check-up cohort. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Hypertension is a leading preventable risk factor of chronic disease and all-cause mortality. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Vaccination with either two doses of the BNT162b2 or one dose of the AZD1222 vaccine leads to lower production of NAbs against SARS-CoV-2 in patients compared with controls both on day 22 and on day 50 (P<0.001 for all comparisons). …”
Enlace del recurso
Enlace del recurso

“…PROBLEM/CONDITION: Homicide is a leading cause of death for American Indians/Alaska Natives (AI/ANs). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: Results suggest that increasing community vaccination coverage leads to fewer infections in NH residents. Testing asymptomatic residents and staff may have limited value when vaccination coverage is high. …”
Enlace del recurso
Enlace del recurso

“…A change from alanine to glutamate in the sensor kinase MadS (madS(A202E)) leads to activation of the system and impaired killing by AMPs. …”
Enlace del recurso
Enlace del recurso