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  1. 490461
    “…Serology evolved with positive ANA, anti-RNP antibodies and positive RF leading to diagnosis of MCTD. Treatment included azathioprine and mycophenolate mofetil (MMF). …”
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    O18 The Rollercoaster Reality of Mixed Connective Tissue disease
  2. 490462
    por Davies, Justine I., Reddiar, Sumithra Krishnamurthy, Hirschhorn, Lisa R., Ebert, Cara, Marcus, Maja-Emilia, Seiglie, Jacqueline A., Zhumadilov, Zhaxybay, Supiyev, Adil, Sturua, Lela, Silver, Bahendeka K., Sibai, Abla M., Quesnel-Crooks, Sarah, Norov, Bolormaa, Mwangi, Joseph K., Omar, Omar Mwalim, Wong-McClure, Roy, Mayige, Mary T., Martins, Joao S., Lunet, Nuno, Labadarios, Demetre, Karki, Khem B., Kagaruki, Gibson B., Jorgensen, Jutta M. A., Hwalla, Nahla C., Houinato, Dismand, Houehanou, Corine, Guwatudde, David, Gurung, Mongal S., Bovet, Pascal, Bicaba, Brice W., Aryal, Krishna K., Msaidié, Mohamed, Andall-Brereton, Glennis, Brian, Garry, Stokes, Andrew, Vollmer, Sebastian, Bärnighausen, Till, Atun, Rifat, Geldsetzer, Pascal, Manne-Goehler, Jennifer, Jaacks, Lindsay M.
    Publicado 2020
    “…BACKGROUND: Cardiovascular diseases are leading causes of death, globally, and health systems that deliver quality clinical care are needed to manage an increasing number of people with risk factors for these diseases. …”
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    Association between country preparedness indicators and quality clinical care for cardiovascular disease risk factors in 44 lower- and middle-income countries: A multicountry analysis of survey data
  3. 490463
    “…Study drug-related AEs occurred in 7% on B/F/TAF; most were grade 1; the most common was headache (1.6%). 7 (1%) participants had an AE leading to premature study drug discontinuation, only 1, headache, occurred in the OL phase. …”
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    1028. Long-term Follow-up After a Switch to Bictegravir, Emtracitabine, Tenofovir Alafenamide from Dolutegravir, Abacavir, Lamivudine
  4. 490464
    “…BACKGROUND: Lower respiratory tract infections (LRTIs) are a leading cause of pediatric morbidity and mortality worldwide, with ~650,000 deaths recorded in < 5-year-olds in 2016. …”
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    1506. Burden of Respiratory Syncytial Virus (RSV) and Other Lower Respiratory Tract Viral Infections During the First Two Years of Life: a Prospective Study
  5. 490465
    “…Excluding injection-site reactions (ISRs), nasopharyngitis (11%), upper respiratory tract infection (11%), diarrhea (10%), and pyrexia (10%) were the most commonly reported adverse events (AEs) in the Q2M arm. 10% (9/90) of Q2M participants reported AEs ≥grade 3; 0 were drug related. 2% (2/90) of Q2M participants had AEs leading to withdrawal. 6% (5/90) of participants reported serious AEs (1 considered drug-related). …”
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    116. Antiviral Activity and Safety of Long-acting Cabotegravir (CAB LA) Plus Long-acting Rilpivirine (RPV LA), Administered Every 2 Months (Q2M), in Hiv-positive Subjects: Results from the POLAR Study
  6. 490466
    “…The median time to conception was 7 months in women with identified and treated IUAs versus 5 months in women without IUAs (hazard ratio (HR) 0.84 (95% CI 0.54 to 1.33)) and time to conception leading to a live birth 15 months versus 5.0 months (HR 0.54 (95% CI: 0.30 to 0.97)). …”
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    Reproductive performance of women with and without intrauterine adhesions following recurrent dilatation and curettage for miscarriage: long-term follow-up of a randomized controlled trial
  7. 490467
    “…We thus find a consistent pattern, which leads us to answer the question about criterion validity (FF1.2) of our virtualized RTR measure in the affirmative. …”
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    Validität und Reliabilität virtualisierter RTR-Messungen
  8. 490468
    por Sewaralthahab, Sarah, Smith, Hedy
    Publicado 2020
    “…Our assumption and hypothesis was that SCD pathology would be exacerbated by SARS CoV-2 infection leading to higher rates of acute chest syndrome (ACS), venous thromboembolism (VTE), more robust inflammatory responses requiring ICU care and increased death rates. …”
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    Outcomes of Sickle Cell Disorders in COVID-19 Infection: An Institutional Experience
  9. 490469
    “…The protein encoded by the NF1 gene, neurofibromin, acts as an inhibitor of both classic Ras and R-Ras proteins; loss of neurofibromin could cause these Ras proteins to become persistently active, leading to the development of cancer. We have previously shown that three related Ras proteins (the classic Ras proteins) are highly activated in malignant peripheral nerve sheath tumor (MPNST) cells with neurofibromin loss and that they drive cancer cell proliferation and survival by activating multiple cellular signaling pathways. …”
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    R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells
  10. 490470
    “…BACKGROUND: Severe bacterial infections (SBIs) are a leading cause of neonatal deaths in low- and middle-income countries (LMICs). …”
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    Severe bacterial neonatal infections in Madagascar, Senegal, and Cambodia: A multicentric community-based cohort study
  11. 490471
    “…Its complications range from corneal opacification to thinning, and it leads to the most severe form of necrotizing keratitis called peripheral ulcerative keratitis (PUK), corneal melting. …”
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    P21 My eye was cloudy at first and I can see it is melting away!
  12. 490472
    por Alveyn, Edward, Mahto, Arti
    Publicado 2021
    “…Perhaps insufficient diagnostic weight was given to her known thrombophilia and recent medication change, which may have prompted closer review of her brain imaging leading to earlier detection of the subdural haematoma. …”
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    O21 A case of thromboembolic ischaemic cardiomyopathy and intracardiac thrombus in a patient with antiphospholipid syndrome
  13. 490473
    “…Introduction: Acquired thrombotic thrombocytopenic purpura (aTTP) due to an acquired deficiency in the enzyme ADAMTS13 leads to ultra-large von Willebrand multimers, thrombocytopenia and microangiopathic hemolytic anemia. …”
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    Relapsed Refractory Acquired Thrombotic Thrombocytopenic Purpura (aTTP) Following COVID-19 Vaccination
  14. 490474
    “…This study suggests that SARS-CoV-2 pneumonia leads to greater endothelial dysfunction than that observed in H3N2/H1N1 viral pneumonia and that race/ethnicity does not drive mortality outcomes. …”
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    Comparison of Clinical and Thrombotic Outcomes in Sars-Cov-2- Pneumonia Versus Other Viral Pneumonia in an Urban Academic Medical Center
  15. 490475
    “…Background: The severe, acute respiratory syndrome, coronavirus 2 (SARS-CoV-2), leading to coronavirus-19 (COVID-19), was detected for the first time in Wuhan, China in December 2019. …”
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    The Impact of the COVID-19 Pandemic on Quality of Life in Danish Patients with Multiple Myeloma; Results from an Ongoing Longitudinal National Survey
  16. 490476
    “…It was performed for the primary outcome of biochemical pregnancy leading to live birth after 12 months of follow-up as well as the secondary outcome of live birth after the second fresh IVF/ICSI treatment (i.e. the first after randomization). …”
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    Economic evaluation of endometrial scratching before the second IVF/ICSI treatment: a cost-effectiveness analysis of a randomized controlled trial (SCRaTCH trial)
  17. 490477
    por Gor, Shivani, Waller, Rosemary
    Publicado 2021
    “…In WM patients with symptomatic cryoglobulinaemia, exposure to cold leads to intravascular gelling of cryoglobulins with subsequent intravascular agglutination of red cells. …”
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    P06 Waldenström macroglobulinemia – beware the label of primary Raynaud’s Phenomenon
  18. 490478
    por Amjad, Qurat Ul Ain, Ellis, Spencer
    Publicado 2021
    “…The dose of HCQ was increased to 400mg daily leading to improvement in the headaches. She had persistent strong ACL antibodies, positive LAC and ab2GPI antibodies. …”
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    O22 Pregnancy planning in non-criteria antiphospholipid syndrome
  19. 490479
    por Kozar, Victoria, Steffens, David
    Publicado 2022
    “…Although loneliness is considered to be a subjective feeling related to a person's experience, it is one of three main factors leading to depression and a factor in cause of suicide. …”
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    Evaluating the Effects of the COVID-19 Pandemic on Depression and Resilience in Older Adults
  20. 490480
    por Zeng, Ning, Hausmann, Henry
    Publicado 2022
    “…Storing wood in many environments is possible, leading to seven versions of Wood Vault: (1) Burial Mound (Tumulus or Barrow), (2) Underground (Pit, Quarry, or Mine), (3) Super Vault, (4) Shelter, (5) AquaOpen or AquaVault with wood submerged under water, (6) DesertOpen or DesertVault in dry regions, (7) FreezeVault in cold regions such as Antarctica. …”
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    Wood Vault: remove atmospheric CO(2) with trees, store wood for carbon sequestration for now and as biomass, bioenergy and carbon reserve for the future
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