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  1. 490501
    “…BACKGROUND: Talaromyces marneffei (Tm), a fungus endemic in Southeast Asia, is a leading cause of death in patients with advanced HIV disease. …”
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    622. Development of Interferon-Gamma Release Assays for Diagnosing Latent Talaromycosis
  2. 490502
    por Puck, Theodore T., Lee, Howard H.
    Publicado 1955
    “…The following experimental results constitute evidence that in the course of normal virus infection, a resealing reaction is rapidly instituted in the cell wall which reverses the effect of the original permeability increase, and renders the cell refractory to a second lytic reaction by a homologous virus: (a) Cell leakage induced by T2 virus in the course of normal infection markedly slows down or stops within a few minutes, even when only a small fraction of the material potentially available for leakage has been released, (b) Superinfection after 8 minutes at 37°C., of a cell previously infected with a homologous virus causes little or no appearance of a second leakage of cell constituents. This experiment also leads to the conclusion that the sealing reaction, like that which causes the leakage, also involves a disturbance which spreads over all or most of the cell wall. …”
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    MECHANISM OF CELL WALL PENETRATION BY VIRUSES : II. DEMONSTRATION OF CYCLIC PERMEABILITY CHANGE ACCOMPANYING VIRUS INFECTION OF ESCHERICHIA COLI B CELLS
  3. 490503
    “…PUBLIC HEALTH ACTION: Eliminating disparities in preconception health can potentially reduce disparities in two of the leading causes of death in early and middle adulthood (i.e., heart disease and diabetes). …”
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    Disparities in Preconception Health Indicators — 
Behavioral Risk Factor Surveillance System, 2013–2015, and Pregnancy Risk Assessment Monitoring System, 2013–2014
  4. 490504
    por Ghuman, Hira, Samaranayaka, Muditha
    Publicado 2019
    “…Shortly after, she suffered a low trauma fracture neck of femur which caused fat emboli leading to a dense stroke. She recovered gradually with anticoagulation. …”
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    49. Giant cell arteritis and Takayasu arteritis: two sides of the same coin in an elderly female?
  5. 490505
    “…Compared to the status quo, by 2030, vaccination alone would have minimal impact on cervical cancer mortality, leading to a 0·1% (0·1–0·5) reduction, but additionally scaling up twice-lifetime screening and cancer treatment would reduce mortality by 34·2% (23·3–37·8), averting 300 000 (300 000–400 000) deaths by 2030 (with similar results for once-lifetime screening). …”
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    Mortality impact of achieving WHO cervical cancer elimination targets: a comparative modelling analysis in 78 low-income and lower-middle-income countries
  6. 490506
    “…The results showed that among severe patients (n=58), 3.4% were current smokers and 6.9% were former smokers, in contrast to non-severe patients (n=82) among which 0% were current smokers and 3.7% were former smokers , leading to an OR of 2.23; (95% CI: 0.65–7.63; p=0.2). …”
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    COVID-19 and smoking: A systematic review of the evidence
  7. 490507
    “…This review suggests that maternal death audit and review may need to be implemented as part of an intervention package which also includes elements such as training of a leading doctor and midwife in each hospital, annual recertification, and quarterly outreach visits by external facilitators to provide supervision and mentorship. …”
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    Death audits and reviews for reducing maternal, perinatal and child mortality
  8. 490508
    “…BACKGROUND: Some people with SARS‐CoV‐2 infection remain asymptomatic, whilst in others the infection can cause mild to moderate COVID‐19 disease and COVID‐19 pneumonia, leading some patients to require intensive care support and, in some cases, to death, especially in older adults. …”
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    Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19 disease
  9. 490509
    “…There is little in the literature about the phenotype or treatment of JIA in adults leading to the relative invisibility of JIA in adult rheumatology and relabelling of JIA as RA. …”
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    O14 Transitions in diagnosis and between services in juvenile idiopathic arthritis: living and learning
  10. 490510
    “…PROBLEM/CONDITION: Salmonella, Shiga toxin–producing Escherichia coli (STEC), and Listeria monocytogenes are the leading causes of multistate foodborne disease outbreaks in the United States. …”
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    Investigations of Possible Multistate Outbreaks of Salmonella, Shiga Toxin–Producing Escherichia coli, and Listeria monocytogenes Infections — United States, 2016
  11. 490511
    “…An early pathogenic mechanism of lung injury in mechanically ventilated, critically ill patients is inflammation-induced pulmonary fibrin deposition, leading to thrombosis of the microvasculature and hyaline membrane formation in the air sacs. …”
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    Nebulised heparin for patients with or at risk of acute respiratory distress syndrome: a multicentre, randomised, double-blind, placebo-controlled phase 3 trial
  12. 490512
    “…We closely collaborated with LexisNexis, which is a leading US data analytics company and a member of our NSF I/UCRC for Advanced Knowledge Enablement. …”
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    Modeling and tracking Covid-19 cases using Big Data analytics on HPCC system platform
  13. 490513
    “…BACKGROUND: The leading causes of mortality globally in children younger than five years of age (under‐fives), and particularly in the regions of sub‐Saharan Africa (SSA) and Southern Asia, in 2018 were infectious diseases, including pneumonia (15%), diarrhoea (8%), malaria (5%) and newborn sepsis (7%) (UNICEF 2019). …”
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    Integrated community case management of childhood illness in low‐ and middle‐income countries
  14. 490514
    “…Approximately 20% of patients develop severe disease that can evolve into acute respiratory distress syndrome leading to respiratory or multiorgan failure, with an overall mortality of up to 4%. …”
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    Using Allogeneic, Off-the-Shelf, Sars-Cov-2-Specific T Cells to Treat High Risk Patients with COVID-19
  15. 490515
    “…INTERPRETATION: An extended interval before the second dose of ChAdOx1 nCoV-19 leads to increased antibody titres. A third dose of ChAdOx1 nCoV-19 induces antibodies to a level that correlates with high efficacy after second dose and boosts T-cell responses. …”
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    Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002)
  16. 490516
    “…BACKGROUND: Tuberculosis is a leading cause of infectious disease‐related death and is one of the top 10 causes of death worldwide. …”
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    Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms
  17. 490517
    por Amjad, Qurat Ul Ain, Ellis, Spencer
    Publicado 2021
    “…Treatment challenges arise when a patient sustains fracture despite a BMD above osteoporosis risk criteria, leading us to consider other variables. She was further investigated for secondary causes of osteoporosis, including endocrine causes, and was found to be vitamin D insufficient, which was replaced prior to further antiresorptive treatment. …”
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    P11 Multiple insufficiency fractures in rheumatoid arthritis
  18. 490518
    “…Clinic operations were significantly reduced in late March due to the coronavirus pandemic, leading to majority telehealth visits and restrictions on clinic-wide shared iPad use. …”
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    The Effects of a Pandemic on Patient Engagement in a Patient-Reported Outcome Platform at Orthopaedic Sports Medicine Centers (106)
  19. 490519
    “…Not only do MM patients develop more frequent infections, but it is one of the leading causes of death for these patients. This population develops more severe COVID-19 due to various mechanisms that impair their ability to fight infection. …”
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    Sars-Cov-2 Antibody Decay Monitoring in mRNA Vaccinated Multiple Myeloma Patients
  20. 490520
    “…While there was some delay in the progression of his disease, new areas of necrosis arose, leading to the patient receiving cyclophosphamide. …”
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    O25 Catastrophic antiphospholipid crisis triggered by anticoagulant switch
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