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1141
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1142por Factor-Litvak, P, Slavkovich, V, Liu, X, Popovac, D, Preteni, E, Capuni-Paracka, S, Hadzialjevic, S, Lekic, V, LoIacono, N, Kline, J, Graziano, J“…Lead (Pb) poisoning has numerous effects on the erythropoietic system, but the precise mechanism whereby high dose exposure causes anemia is not entirely clear. …”
Publicado 1998
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1143“…Trail, Canada, has been the site of an active lead/zinc smelter for nearly a century. Since 1991, the Trail Community Lead Task Force has carried out blood lead screening, case management, education programs targeted at early childhood groups and the general community, community dust abatement, exposure pathways studies, and remedial trials. …”
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1144“…Children attending schools in urban areas with high traffic density are a high risk group for lead poisoning. We assessed the magnitude of lead exposure in schoolchildren from Jakarta by analyzing blood lead concentrations and biomarkers of heme biosynthesis. …”
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1145“…This review shows the equal or greater importance of leaded gasoline-contaminated dust compared to lead-based paint to the child lead problem, and that soil lead, resulting from leaded gasoline and pulverized lead-based paint, is at least or more important than lead-based paint (intact and not pulverized) as a pathway of human lead exposure. …”
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1146“…This has motivated the researchers at the University of Cincinnati Department of Environmental Health to be guided by a theoretical model for movement of lead from distal sources (exterior soil or dust and paint lead) to proximal sources (interior dust lead) and then finally to biologic outcomes (handwipe and blood lead). …”
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1147“…Among U.S. children aged 1-5 years, the mean blood lead level was 2.7 microgram/dl, and 890,000 of these children (4.4%) had elevated blood lead levels. …”
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1148“…The Yugoslavia Prospective Study of environmental lead exposure has studied the associations between exposure to lead and pregnancy outcomes; childhood neuropsychological, behavioral, and physical development; and hematologic, renal, and cardiovascular function. …”
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1149“…High-dose lead exposure in rodents has been shown to produce pathognomonic lead intranuclear inclusion bodies and to result in an increased incidence of renal adenocarcinomas. …”
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1150por Verity, M A“…Environmental and occupational exposure to lead still generates concern, and recent studies have focused such concern on the role of body burden of lead during the fetal/neonatal period, especially in the genesis of disturbed central nervous system development. …”
Publicado 1990
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1151“…The effects of lead on the development of the nervous system are of immediate concern to human health. …”
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1152por Dietrich, K N, Succop, P A, Bornschein, R L, Krafft, K M, Berger, O, Hammond, P B, Buncher, C R“…A prospective methodology was used to assess the neurobehavioral effects of fetal and postnatal lead exposure during the first 2 years of life. Lead was measured in whole blood prenatally in mothers and at quarterly intervals in the infant. …”
Publicado 1990
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1153por Brusick, David J.“…Quantitative estimation of germ cell risk based on such available assays is difficult to make and may lead to incorrect assumptions of risk. Better assessment of germ cell genetic damage will require expansion of present procedures to increase sensitivity and the development of improved assay systems.…”
Publicado 1978
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1154por McCabe, E B“…With the focus shifting from children with dangerously elevated body lead burdens to those with less significant exposures, increased attention has been directed to the various inherent metabolic and physical characteristics of the young that may influence the toxic effects of lead exposure. …”
Publicado 1979
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1155por Piver, W T“…The use of a mass balance equation assists in clarifying the contribution of automotive-emitted lead to the regional and global problems of the distribution of this element, by taking into account the physicochemical transformation processes operating on the lead during its transport along the various environmental pathways. …”
Publicado 1977
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1156
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1157
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1158por Kosnett, Michael J., Wedeen, Richard P., Rothenberg, Stephen J., Hipkins, Karen L., Materna, Barbara L., Schwartz, Brian S., Hu, Howard, Woolf, Alan“…Research conducted in recent years has increased public health concern about the toxicity of lead at low dose and has supported a reappraisal of the levels of lead exposure that may be safely tolerated in the workplace. …”
Publicado 2007
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1159por Whitfield, John B., Dy, Veronica, McQuilty, Robert, Zhu, Gu, Montgomery, Grant W., Ferreira, Manuel A.R., Duffy, David L., Neale, Michael C., Heijmans, Bas T., Heath, Andrew C., Martin, Nicholas G.“…BACKGROUND: Lead is an environmental pollutant that causes acute and chronic toxicity. …”
Publicado 2007
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1160