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3681por Aghaei, Maryam, Khanahmad, Hossein, Jalali, Akram, Aghaei, Shahrzad, Narimani, Manizheh, Hosseini, Sayed Mohsen, Namdar, Fatemeh, Hejazi, Seyed Hossein“…OBJECTIVE(S): Leishmaniasis is a complex infection against which no confirmed vaccine has been reported so far. …”
Publicado 2021
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3682por Volpedo, Greta, Bhattacharya, Parna, Gannavaram, Sreenivas, Pacheco-Fernandez, Thalia, Oljuskin, Timur, Dey, Ranadhir, Satoskar, Abhay R., Nakhasi, Hira L.“…Current treatments for leishmaniasis are not highly efficacious and are associated with high costs, especially in low- and middle-income endemic countries, and high toxicity. …”
Publicado 2022
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3683por Chacón-Vargas, Karla Fabiola, Sánchez-Torres, Luvia Enid, Chávez-González, Mónica L., Adame-Gallegos, Jaime R., Nevárez-Moorillón, Guadalupe Virginia“…Leishmaniasis is a neglected vector-borne disease; there are different manifestations of the diseases and species involved, and cutaneous leishmaniasis caused by Leishmania (L.) mexicana is the most prevalent in Mexico. …”
Publicado 2022
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3684por Mata-Somarribas, Carlos, Quesada-López, José, Matamoros, María F, Cervantes-Gómez, César, Mejía, Annia, Chacón, Karen, Bendig, Ivannia, Campos, Roger, Quesada-Morera, Raphael, Cantanhêde, Lilian Motta, Pereira, Luiza de Oliveira R, Cupolillo, Elisa“…The possibility of its local dispersion represents one more challenge faced by regional health authorities in preventing and controlling leishmaniasis.…”
Publicado 2023
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3685por de Sá, Keyla S. G., Amaral, Luana A., Rodrigues, Tamara S., Ishimoto, Adriene Y., de Andrade, Warrison A. C., de Almeida, Leticia, Freitas-Castro, Felipe, Batah, Sabrina S., Oliveira, Sergio C., Pastorello, Mônica T., Fabro, Alexandre T., Zamboni, Dario S.“…Intracellular parasites from the Leishmania genus cause Leishmaniasis, a disease affecting millions of people worldwide. …”
Publicado 2023
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3686por Usman, Mahmud, Natala, Audu Joseph, Jatau, Isa Danladi, Ogo, Ndudim Isaac, Jeelani, Ghulam, Goto, Yasuyuki, Nozaki, Tomoyoshi, McKerrow, James H., Balogun, Emmanuel Oluwadare“…INTRODUCTION: Female sand flies are hematophagous, feeding on animals and in the process serve as vectors for Leishmania, the parasites that cause leishmaniasis in humans. Leishmaniasis are a group of parasitic neglected tropical diseases in 98 countries including Nigeria and kills ~60,000 people/year. …”
Publicado 2023
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3687“…Visceral leishmaniasis (VL), caused by Leishmania donovani, is the most severe form of leishmaniasis with high rates of mortality if left untreated. …”
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3688por Franco, Antonia MR, Grafova, Iryna, Soares, Fabiane V, Gentile, Gennaro, Wyrepkowski, Claudia DC, Bolson, Marcos A, Sargentini, Ézio, Carfagna, Cosimo, Leskelä, Markku, Grafov, Andriy“…BACKGROUND: Coordination compounds of pentavalent antimony have been, and remain, the first-line drugs in leishmaniasis treatment for >70 years. Molecular forms of Sb (V) complexes are commercialized as sodium stibogluconate (Pentostam(®)) and meglumine antimoniate (MA) (Glucantime(®)). …”
Publicado 2016
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3689por Zimara, Nicole, Chanyalew, Menberework, Aseffa, Abraham, van Zandbergen, Ger, Lepenies, Bernd, Schmid, Maximilian, Weiss, Richard, Rascle, Anne, Wege, Anja Kathrin, Jantsch, Jonathan, Schatz, Valentin, Brown, Gordon D., Ritter, Uwe“…However, little is known about the function of the CLR Dectin-1 in modulating Th1- or Th2-type immune responses by DC subsets in leishmaniasis. We characterized the expression of Dectin-1 on CD11c(+) DCs in peripheral blood, at the site of infection, and skin-draining lymph nodes of L. major-infected C57BL/6 and BALB/c mice and in peripheral blood of patients suffering from cutaneous leishmaniasis (CL). …”
Publicado 2018
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3690por Fernández, Laura, Carrillo, Eugenia, Sánchez-Sampedro, Lucas, Sánchez, Carmen, Ibarra-Meneses, Ana Victoria, Jimenez, Mͣ Angeles, Almeida, Valter dos Anjos, Esteban, Mariano, Moreno, Javier“…Leishmania-activated C-kinase antigen (LACK) is a highly conserved protein among Leishmania species and is considered a viable vaccine candidate for human leishmaniasis. In animal models, prime-boost vaccination with LACK-expressing plasmids plus attenuated vaccinia viruses (modified vaccinia Ankara [MVA] and mutant M65) expressing LACK, has been shown to protect against cutaneous leishmaniasis (CL). …”
Publicado 2018
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3691por Samarasinghe, Sumudu R., Samaranayake, Nilakshi, Kariyawasam, Udeshika L., Siriwardana, Yamuna D., Imamura, Hideo, Karunaweera, Nadira D.“…BACKGROUND: Leishmaniasis is a neglected tropical disease with diverse clinical phenotypes, determined by parasite, host and vector interactions. …”
Publicado 2018
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3692por Gunaratna, Gayana, Manamperi, Aresha, Böhlken-Fascher, Susanne, Wickremasinge, Renu, Gunawardena, Kithsiri, Yapa, Bandujith, Pathirana, Nishantha, Pathirana, Hasantha, de Silva, Nilanthi, Sooriyaarachchi, Monica, Deerasinghe, Theja, Mondal, Dinesh, Ranasinghe, Shalindra, Abd El Wahed, Ahmed“…BACKGROUND: Leishmaniasis is a disease caused by vector-borne protozoans. …”
Publicado 2018
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3693por López, Marla, Erazo, Diana, Hoyos, Juliana, León, Cielo, Fuya, Patricia, Lugo, Ligia, Cordovez, Juan Manuel, González, Camila“…The overall results could support the understanding of the current transmission cycles of Leishmaniasis in Colombia.…”
Publicado 2021
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3694por Zheng, Zhiwan, He, Jinlei, Luo, Tao, Zhang, Jianhui, Zhou, Qi, Yin, Shuangshuang, Chen, Dali, Luo, Jie, Chen, Jianping, Li, Jiao“…SIMPLE SUMMARY: Leishmaniasis, a neglected tropical disease, is caused by infection with the Leishmania species, threatening millions of people in approximately 100 endemic countries. …”
Publicado 2022
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3695por Hassan, Abdalla A., Khalid, Hassan E., Abdalla, Abdelwahab H., Mukhtar, Maowia M., Osman, Wadah J., Efferth, Thomas“…Leishmaniasis is one of the most neglected tropical diseases that present areal public health problems worldwide. …”
Publicado 2022
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3696por Borges, Beatriz Santana, Bueno, Gislayne de Paula, Tomiotto-Pellissier, Fernanda, Figueiredo, Fabiano Borges, Soares Medeiros, Lia Carolina“…INTRODUCTION: Leishmaniasis is a neglected tropical disease, with approximately 1 million new cases and 30,000 deaths reported every year worldwide. …”
Publicado 2023
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3697por Grabmeier-Pfistershammer, K., Poeppl, W., Brunner, P. M., Rappersberger, K., Rieger, A.“…We report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease. …”
Publicado 2012
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3698por Sekhon, B. S.“…Pentavalent antimonials have been the recommended drug for visceral leishmaniasis and cutaneous leishmaniasis. Tellurium (IV) compounds may have important roles in thiol redox biological activity in the human body, and ammonium trichloro (dioxoethylene-O, O’-)tellurate (AS101) may be a promising agent for the treatment of Parkinson’s disease. …”
Publicado 2013
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3699“…Visceral leishmaniasis should be considered in cases of marked splenomegaly, anemia, and thrombocytopenia, especially with a history of visiting an endemic area.…”
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3700por Pocholle, E., Reyes-Gomez, E., Giacomo, A., Delaunay, P., Hasseine, L., Marty, P.“…We report a case of disseminated feline leishmaniasis in a FIV-seropositive 14-year-old male cat (Felis catus) living in the Alpes-Maritimes (south of France). …”
Publicado 2012
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