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3841por Domeneghetti, L., Demarchi, I. G., Caitano, J. Z., Pedroso, R. B., Silveira, T. G. V., Lonardoni, M. V. C.“…Calophyllum brasiliense is a plant from the Brazilian rain forests and has been used in folk medicine for the treatment of various diseases, including leishmaniasis. This infectious disease depends on the Leishmania sp. and the host immune response. …”
Publicado 2018
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3842“…Interestingly, this compound enhanced the anti-leishmanial Sb(III) effect, indicating that this combination represents a good strategy for leishmaniasis chemotherapy. Our data demonstrate that APX enzyme is involved in the development of L. braziliensis antimony-resistance phenotype and may be an attractive therapeutic target in the design of new strategies for leishmaniasis treatment.…”
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3843por dos Santos, Vania A. F. F. M., Leite, Karoline M., da Costa Siqueira, Mariana, Regasini, Luis O., Martinez, Isabel, Nogueira, Camila T., Galuppo, Mariana Kolos, Stolf, Beatriz S., Pereira, Ana Maria Soares, Cicarelli, Regina M. B., Furlan, Maysa, Graminha, Marcia A. S.“…The data here presented suggests that these compounds should be considered in the development of new and more potent drugs for the treatment of leishmaniasis and Chagas’ disease.…”
Publicado 2013
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3844por Eggimann, Gabriela A., Sweeney, Kathryn, Bolt, Hannah L., Rozatian, Neshat, Cobb, Steven L., Denny, Paul W.“…Natural product antimicrobial peptides (AMPs) have been proposed as promising agents against the Leishmania species, insect vector borne protozoan parasites causing the neglected tropical disease leishmaniasis. However, recent studies have shown that the mammalian pathogenic amastigote form of L. mexicana, a causative agent of cutaneous leishmaniasis, is resistant to the amphibian-derived temporin family of AMPs when compared to the insect stage promastigote form. …”
Publicado 2015
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3845por Castro, J.C., Bueno, L.L., Milagres, T.F., Rêgo, F.D., Gontijo, C.M.F., Peconick, A.P., Andrade, A.J., Barçante, T.A., Barçante, J.M.P.“…Leishmaniasis is a neglected disease that affects a large part of the world population. …”
Publicado 2019
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3846por Gomes, Jacinto, Rocha, Hugo, Carvalho, Carina, Bandeira, Victor, Fonseca, Carlos, Rosalino, Luís Miguel, Cunha, Mónica V.“…Wild mammals are susceptible to infection by Leishmania parasites. Although canine leishmaniasis is widely distributed in mainland Portugal, the sylvatic cycle of the parasite remains poorly understood. …”
Publicado 2020
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3847“…The field-based studies on sand flies are not adequate to uncover information required for the control of the leishmaniasis through reduction of vector populations. …”
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3848por Latifi, Alireza“…OBJECTIVE: Miltefosine is an anti-cancer drug used to treat leishmaniasis and deadly opportunistic free-living amoeba and other deadly pathogenic microorganisms. …”
Publicado 2020
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3849por El-Dirany, Rima, Shahrour, Hawraa, Dirany, Zeinab, Abdel-Sater, Fadi, Gonzalez-Gaitano, Gustavo, Brandenburg, Klaus, Martinez de Tejada, Guillermo, Nguewa, Paul A.“…Their anti-parasitic effect against leishmaniasis has been studied. Leishmaniasis is a neglected tropical disease. …”
Publicado 2021
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3850“…These results expand the current knowledge of aminopeptidase biochemistry and highlight that specific actinonin or peptidomimetic-based inhibitors may emerge as leads to combat leishmaniasis.…”
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3851“…Leishmaniasis is a vector-borne disease caused by a protozoa parasite from over 20 Leishmania species. …”
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3852por Amlabu, Wandayi Emmanuel, Amisigo, Cynthia Mmalebna, Antwi, Christine Achiaa, Awandare, Gordon Akanzuwine, Gwira, Theresa Manful“…Leishmaniasis is a disease closely associated with poverty and endemic in Africa, Asia, southern Europe and the Americas. …”
Publicado 2021
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3853por Bethencourt-Estrella, Carlos J., Nocchi, Nathalia, López-Arencibia, Atteneri, San Nicolás-Hernández, Desirée, Souto, María L., Suárez-Gómez, Blanca, Díaz-Marrero, Ana R., Fernández, José J., Lorenzo-Morales, Jacob, Piñero, José E.“…Leishmaniasis and Chagas disease are neglected tropical diseases that cause problems in developing countries. …”
Publicado 2021
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3854por Patiño, Luz H, Muñoz, Marina, Pavia, Paula, Muskus, Carlos, Shaban, Maryia, Paniz-Mondolfi, Alberto, Ramírez, Juan David“…Insufficient and irregular data reports on Leishmaniasis, issuing from the developing world, have left much to be desired in terms of understanding the molecular signatures producing distinct infectious phenotypes of the disease. …”
Publicado 2021
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3855por El Idrissi Saik, Imane, Benlabsir, Chaimaa, Fellah, Hassan, Lemrani, Meryem, Riyad, Myriam“…Cutaneous leishmaniasis (CL) due to Leishmania tropica is a neglected tropical disease characterized by a wide geographical distribution in the Mediterranean basin and is endemic in several of its countries. …”
Publicado 2022
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3856por Cabello-Donayre, María, Orrego, Lina M., Herráez, Elisa, García-Hernández, Raquel, Pérez-Victoria, José M.“…The protozoan parasite Leishmania, responsible for leishmaniasis, is one of the few aerobic organisms that cannot synthesize the essential molecule heme. …”
Publicado 2022
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3857“…BACKGROUND: Leishmania is a parasite causing leishmaniasis with different clinical manifestations depending on the infectious species in many countries worldwide. …”
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3858por Medenica, Sanja, Miladinović-Tasić, Nataša, Stojanović, Nikola M., Lakićević, Novak, Rakočević, Božidarka“…Leishmaniosis (or leishmaniasis) is a neglected parasitosis most commonly transmitted by the sandfly bite. …”
Publicado 2023
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3859por Ketema, Tasisa, Tadele, Markos, Gebrie, Zewdie, Makonnen, Eyasu, Hailu, Asrat, Abay, Solomon M“…INTRODUCTION: Leishmaniasis is one of the neglected tropical diseases, threatening lives of about 350 million people globally. …”
Publicado 2023
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3860por Burguete-Mikeo, Aroia, Fernández-Rubio, Celia, Peña-Guerrero, José, El-Dirany, Rima, Gainza, Leonardo, Carasa Buj, Belen, Nguewa, Paul A.“…SIMPLE SUMMARY: Leishmaniasis is a group of parasitic diseases that affect humans and animals. …”
Publicado 2023
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