Mostrando 3,921 - 3,940 Resultados de 6,219 Para Buscar '"leishmaniasis"', tiempo de consulta: 0.19s Limitar resultados
  1. 3921
  2. 3922
  3. 3923
  4. 3924
  5. 3925
  6. 3926
    “…We have recently found that Vorinostat derivatives (O-alkyl hydroxamates) are active against Leishmania infantum intracellular forms and effective in laboratory models of visceral leishmaniasis without producing toxicity. We designed a clinical trial with 18 dogs naturally infected with the parasite and demonstrated that our flagship compound, MTC-305, is superior to the current first-line treatment of canine leishmaniasis, meglumine antimoniate, at reducing the parasite numbers in target organs (bone marrow, lymph nodes and blood) and improving the dogs’ clinical state. …”
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  7. 3927
    “…Due to the lack of specific vaccines, management of the trypanosomatid-caused neglected tropical diseases (sleeping sickness, Chagas disease and leishmaniasis) relies exclusively on pharmacological treatments. …”
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  8. 3928
  9. 3929
    “…Sand flies (Diptera: Psychodidae) serve as vectors for transmitting protozoan parasites, Leishmania spp., that cause the disease called leishmaniasis. The main approach to controlling sand flies is the use of chemical insecticides. …”
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  10. 3930
  11. 3931
    “…Mediterranean spotted fever (Rickettsia conorii) and murine typhus (Rickettsia typhi) are the main rickettsial infections in Croatia. Human leishmaniasis is notified sporadically, while serologic evidence of leishmaniasis was found in 11.4% of the Croatian population. …”
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  12. 3932
  13. 3933
  14. 3934
    por Chang, K-P, Dwyer, DM
    Publicado 1978
    “…An in vitro system was developed for studying host-parasite cellular interactions in visceral leishmaniasis with amastigotes isolated from infected spleens of hamsters and their peritoneal macrophages maintained by an improved method. …”
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  15. 3935
    “…Drugs currently available for leishmaniasis treatment often show parasite resistance, highly toxic side effects and prohibitive costs commonly incompatible with patients from the tropical endemic countries. …”
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  16. 3936
    “…Protozoan parasites of genus Leishmania are the causative agents of leishmaniasis. These digenetic microorganisms undergo a marked environmental temperature shift (TS) during transmission from the sandfly vector (ambient temperature, 25–26°C) to the mammalian host (37°C). …”
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  17. 3937
    “…Visceral leishmaniasis is a major neglected tropical disease, with an estimated 500,000 new cases and more than 50,000 deaths attributable to this disease every year. …”
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  18. 3938
    “…The immune parameters induced against LACK and triggered by the combined vaccination DNA/MVA protocol, like polyfunctionality of CD4(+) and CD8(+) T cells with an effector phenotype, could be relevant in protection against leishmaniasis.…”
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  19. 3939
    “…BACKGROUND: Visceral leishmaniasis is caused by Leishmania infantum, transmitted to humans by bites of phlebotomine sand flies and is one of the most important public health problems in Iran. …”
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  20. 3940
    “…Growing of drug unresponsiveness in leishmaniasis patients necessitates the development of new drugs and accordingly a suitable assay is needed for evaluation of any modalities. …”
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