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3921por García-Bermejo, Isabel, Arana, David Molina, Zaragoza Vargas, Gloria, Carrasco Fernández, Blanca, García, Emilia, Nieto, Javier, Flores-Chávez, Maria Delmans“…The high specificity of both assays is useful in areas where leishmaniasis is endemic.…”
Publicado 2022
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3922por Babuadze, Giorgi, Farlow, Jason, de Koning, Harry P., Carrillo, Eugenia, Chakhunashvili, Giorgi, Murskvaladze, Mari, Kekelidze, Merab, Karseladze, Irakli, Kokaia, Nora, Kalandadze, Irine, Tsereteli, David, Markhvashvili, Ivane, Sidamonidze, Ketevan, Chanturia, Gvantsa, Adeishvili, Ekaterine, Imnadze, Paata“…BACKGROUND: Leishmaniasis includes multiple clinical syndromes, most notably visceral, cutaneous, and mucosal forms. …”
Publicado 2016
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3923por Gholami, Elham, Oliveira, Fabiano, Taheri, Tahereh, Seyed, Negar, Gharibzadeh, Safoora, Gholami, Nasim, Mizbani, Amir, Zali, Fatemeh, Habibzadeh, Sima, Bakhadj, Daniel Omid, Meneses, Claudio, Kamyab-Hesari, Kambiz, Sadeghipour, Alireza, Taslimi, Yasaman, khadir, Fatemeh, Kamhawi, Shaden, Mazlomi, Mohammad Ali, Valenzuela, Jesus G., Rafati, Sima“…BACKGROUND: The vector-borne disease leishmaniasis is transmitted to humans by infected female sand flies, which transmits Leishmania parasites together with saliva during blood feeding. …”
Publicado 2019
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3924por Quintana, María Gabriela, Santini, María Soledad, Cavia, Regino, Martínez, Mariela Florencia, Liotta, Domingo Javier, Fernández, María Soledad, Pérez, Adriana Alicia, Mancini, José Manuel Direni, Moya, Sofía Lorian, Giuliani, Magalí Gabriela, Salomón, Oscar Daniel“…BACKGROUND: In South America, cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL) are emerging diseases, expanding in the border area of Argentina, Brazil and Paraguay. …”
Publicado 2020
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3925por Valdivia, Hugo O., Zorrilla, Victor O., Espada, Liz. J., Perez, Jocelyn G., Razuri, Hugo R., Vera, Hubert, Fernandez, Roberto, Tong, Carlos, Ghersi, Bruno M., Vasquez, Gissella M., Burrus, Roxanne G., Lescano, Andres G., Montgomery, Joel M.“…In order to assess leishmaniasis transmission risk along this highway, we conducted a surveillance study of the sand fly populations in this area. …”
Publicado 2021
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3926por Corpas-López, Victoriano, Díaz-Sáez, Victoriano, Morillas-Márquez, Francisco, Franco-Montalbán, Francisco, Díaz-Gavilán, Mónica, López-Viota, Julián, López-Viota, Margarita, Gómez-Vidal, José Antonio, Martín-Sánchez, Joaquina“…We have recently found that Vorinostat derivatives (O-alkyl hydroxamates) are active against Leishmania infantum intracellular forms and effective in laboratory models of visceral leishmaniasis without producing toxicity. We designed a clinical trial with 18 dogs naturally infected with the parasite and demonstrated that our flagship compound, MTC-305, is superior to the current first-line treatment of canine leishmaniasis, meglumine antimoniate, at reducing the parasite numbers in target organs (bone marrow, lymph nodes and blood) and improving the dogs’ clinical state. …”
Publicado 2022
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3927Further Investigations of Nitroheterocyclic Compounds as Potential Antikinetoplastid Drug Candidatespor García-Estrada, Carlos, Pérez-Pertejo, Yolanda, Domínguez-Asenjo, Bárbara, Holanda, Vanderlan Nogueira, Murugesan, Sankaranarayanan, Martínez-Valladares, María, Balaña-Fouce, Rafael, Reguera, Rosa M.“…Due to the lack of specific vaccines, management of the trypanosomatid-caused neglected tropical diseases (sleeping sickness, Chagas disease and leishmaniasis) relies exclusively on pharmacological treatments. …”
Publicado 2023
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3928por Weber, Juliana Inês, Rodrigues, Armanda Viana, Valério-Bolas, Ana, Nunes, Telmo, Carvalheiro, Manuela, Antunes, Wilson, Alexandre-Pires, Graça, da Fonseca, Isabel Pereira, Santos-Gomes, Gabriela“…Leishmaniasis is a parasitic disease caused by different species of Leishmania and transmitted through the bite of sand flies vector. …”
Publicado 2023
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3929“…Sand flies (Diptera: Psychodidae) serve as vectors for transmitting protozoan parasites, Leishmania spp., that cause the disease called leishmaniasis. The main approach to controlling sand flies is the use of chemical insecticides. …”
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3930por Costa, Natalia C. S., dos Anjos, Luana Ribeiro, de Souza, João Victor Marcelino, Brasil, Maria Carolina Oliveira de Arruda, Moreira, Vitor Partite, Graminha, Marcia A. S., Lubec, Gert, Gonzalez, Eduardo Rene P., Cilli, Eduardo Maffud“…[Image: see text] Leishmaniasis refers to a collection of diseases caused by protozoa from the Leishmania genus. …”
Publicado 2023
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3931por Vilibic-Cavlek, Tatjana, Janev-Holcer, Natasa, Bogdanic, Maja, Ferenc, Thomas, Vujica Ferenc, Mateja, Krcmar, Stjepan, Savic, Vladimir, Stevanovic, Vladimir, Ilic, Maja, Barbic, Ljubo“…Mediterranean spotted fever (Rickettsia conorii) and murine typhus (Rickettsia typhi) are the main rickettsial infections in Croatia. Human leishmaniasis is notified sporadically, while serologic evidence of leishmaniasis was found in 11.4% of the Croatian population. …”
Publicado 2023
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3932por Xhekaj, Betim, Hoxha, Ina, Platzgummer, Katharina, Kniha, Edwin, Walochnik, Julia, Sherifi, Kurtesh, Rexhepi, Agim, Behluli, Behlul, Dvořák, Vit, Fuehrer, Hans-Peter, Obwaller, Adelheid G., Poeppl, Wolfgang, Stefanovska, Jovana, Cvetkovikj, Aleksandar“…The Mediterranean sand fly fauna is diverse, and leishmaniasis, mainly caused by Leishmania infantum, is endemic in the Balkan countries. …”
Publicado 2023
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3933por Sharma, Harshita, Sehgal, Rakesh, Shekhar, Nishant, Shoeran, Gaurav, Kaur, Upninder, Medhi, Bikash“…Leishmaniasis is a vector-borne parasitic infection caused by the infective bite of female Phlebotomine sandflies. …”
Publicado 2023
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3934“…An in vitro system was developed for studying host-parasite cellular interactions in visceral leishmaniasis with amastigotes isolated from infected spleens of hamsters and their peritoneal macrophages maintained by an improved method. …”
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3935por Siqueira-Neto, Jair L., Song, Ok-Ryul, Oh, Hyunrim, Sohn, Jeong-Hun, Yang, Gyongseon, Nam, Jiyoun, Jang, Jiyeon, Cechetto, Jonathan, Lee, Chang Bok, Moon, Seunghyun, Genovesio, Auguste, Chatelain, Eric, Christophe, Thierry, Freitas-Junior, Lucio H.“…Drugs currently available for leishmaniasis treatment often show parasite resistance, highly toxic side effects and prohibitive costs commonly incompatible with patients from the tropical endemic countries. …”
Publicado 2010
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3936“…Protozoan parasites of genus Leishmania are the causative agents of leishmaniasis. These digenetic microorganisms undergo a marked environmental temperature shift (TS) during transmission from the sandfly vector (ambient temperature, 25–26°C) to the mammalian host (37°C). …”
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3937“…Visceral leishmaniasis is a major neglected tropical disease, with an estimated 500,000 new cases and more than 50,000 deaths attributable to this disease every year. …”
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3938por Sánchez-Sampedro, Lucas, Gómez, Carmen Elena, Mejías-Pérez, Ernesto, S. Sorzano, Carlos Oscar, Esteban, Mariano“…The immune parameters induced against LACK and triggered by the combined vaccination DNA/MVA protocol, like polyfunctionality of CD4(+) and CD8(+) T cells with an effector phenotype, could be relevant in protection against leishmaniasis.…”
Publicado 2012
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3939por Dehkordi, A Sanei, Rassi, Y, Oshaghi, MA, Abai, MR, Rafizadeh, S, Yaghoobi-Ershadi, MR, Mohebali, M, Zarei, Z, Mohtarami, F, Jafarzadeh, B, Ranjbarkhah, A, Javadian, E“…BACKGROUND: Visceral leishmaniasis is caused by Leishmania infantum, transmitted to humans by bites of phlebotomine sand flies and is one of the most important public health problems in Iran. …”
Publicado 2011
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3940“…Growing of drug unresponsiveness in leishmaniasis patients necessitates the development of new drugs and accordingly a suitable assay is needed for evaluation of any modalities. …”
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