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  1. 3961
    “…[Image: see text] Tuberculosis and parasitic diseases, such as giardiasis, amebiasis, leishmaniasis, and trypanosomiasis, all urgently require improved treatment options. …”
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    Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity
  2. 3962
    “…BACKGROUND: Leishmaniasis caused by protozoan parasite Leishmania is a neglected disease which is endemic in the northwest of China. …”
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    Multi-locus characterization and phylogenetic inference of Leishmania spp. in snakes from Northwest China
  3. 3963
    “…Lastly, we also present data on the associations between seroconversion and the type of leishmaniasis.…”
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    Evaluation of the NovaLisa™ Leishmania Infantum IgG ELISA in A Reference Diagnostic Laboratory in A Non-Endemic Country
  4. 3964
    “…Leishmaniasis is a group of neglected tropical diseases caused by protozoan parasites of the Leishmania genus. …”
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    Bixa orellana L. (Bixaceae) and Dysphania ambrosioides (L.) Mosyakin & Clemants (Amaranthaceae) Essential Oils Formulated in Nanocochleates against Leishmania amazonensis
  5. 3965
    “…Leishmaniasis remains a major world health problem, and in particular, Algeria ranks second for the incidence of cutaneous leishmaniasis. …”
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    Antioxidant and Leishmanicidal Evaluation of Pulicaria Inuloides Root Extracts: A Bioguided Fractionation
  6. 3966
    “…Leishmaniasis is endemic in at least 98 countries. Due to the high toxicity and resistance associated with the drugs, we chose lignans as an alternative, due to their favorable properties of absorption, distribution, metabolism, excretion, and toxicity (ADMET). …”
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    Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans
  7. 3967
    “…Leishmania (Leishmania) infantum is the etiological agent of both American visceral leishmaniasis (AVL) and non-ulcerated cutaneous leishmaniasis (NUCL) in Honduras. …”
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    Clinical and Immunological Features of Human Leishmania (L.) infantum-Infection, Novel Insights Honduras, Central America
  8. 3968
    “…The protozoan parasite Leishmania (Viannia) braziliensis (L. braziliensis) is the main cause of human tegumentary leishmaniasis in the New World, a disease affecting the skin and/or mucosal tissues. …”
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    Application of CRISPR/Cas9-Based Reverse Genetics in Leishmania braziliensis: Conserved Roles for HSP100 and HSP23
  9. 3969
    “…A subset of analogues showed an improved potency (EC(50) 0.5–10 µM) and selectivity (20–35) against the clinically relevant stage of Leishmania braziliensis (mucocutaneous leishmaniasis) and L. infantum (visceral leishmaniasis). …”
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    Mechanistic and biological characterisation of novel N(5)-substituted paullones targeting the biosynthesis of trypanothione in Leishmania
  10. 3970
    “…We will also discuss the distinct involvement of neutrophils in the outcome of leishmaniasis.…”
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    The Impact of Neutrophil Recruitment to the Skin on the Pathology Induced by Leishmania Infection
  11. 3971
    “…Many of the analogues prepared were shown to be more potent than pulchrol and the current drugs used to treat leishmaniasis and Chagas disease (miltefosine and benznidazole, respectively), in vitro. …”
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    SARs for the Antiparasitic Plant Metabolite Pulchrol. 3. Combinations of New Substituents in A/B-Rings and A/C-Rings
  12. 3972
    “…BACKGROUND: Trypanosomatids are widespread and cause diseases - such as trypanosomiasis, sleeping sickness, Chagas disease, and cutaneous and visceral leishmaniasis - in animals and humans. These diseases occur in both rural and urban regions due to unplanned growth and deforestation. …”
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    Presence of trypanosomatids, with emphasis on Leishmania, in Rodentia and Didelphimorphia mammals of a rural settlement in the central Amazon region
  13. 3973
    “…The results presented reinforce the importance of these species in anthropized areas in the transmission of cutaneous leishmaniasis (CL) agents and the need for entomological monitoring. …”
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    Updating Ecological and Behavioral Aspects of the Sandfly Fauna in the Vale do Ribeira Region, São Paulo State, Brazil
  14. 3974
    “…Most species develop in a hematophagous arthropod and infect a specific vertebrate host that may belong to diverse orders and families. Visceral leishmaniasis is a chronic zoonosis with a wide geographic distribution, affecting 350 million people globally, mostly in areas with a high risk of infection. …”
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    First molecular-based detection study of Leishmania infantum in the Tapirapé indigenous population in the Brazilian Amazon
  15. 3975
    “…Background: Leishmaniasis, a vector-borne disease caused by the protozoan parasite from the genus Leishmania, is endemic to tropical and subtropical areas. …”
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    Minor Impact of A258D Mutation on Biochemical and Enzymatic Properties of Leishmania infantum GDP-Mannose Pyrophosphorylase
  16. 3976
    “…We have previously shown that HSPC activation promotes parasite persistence and expansion in experimental visceral leishmaniasis through the increased production of permissive monocytes. …”
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    Persistent Cutaneous Leishmania major Infection Promotes Infection-Adapted Myelopoiesis
  17. 3977
    “…Leishmania infantum is a protozoan causing human zoonotic visceral leishmaniasis (ZVL) and visceral–cutaneous canine leishmaniosis (CanL) in the Mediterranean Basin. …”
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    Detection of Leishmania spp. in Chronic Dermatitis: Retrospective Study in Exposed Horse Populations
  18. 3978
    “…INTRODUCTION: Leishmaniasis is still a neglected tropical disease that can endanger more than 350 million people among 98 countries. …”
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    Superparamagnetic Iron Oxide-Labeled Leishmania major Can Be Traced in Fibroblasts
  19. 3979
    “…Leishmaniasis is a vector-borne disease caused by an intracellular parasite of the genus Leishmania with different clinical manifestations that affect millions of people worldwide, while the visceral form may be fatal if left untreated. …”
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    Immunoinformatics Approach to Design a Multi-Epitope Nanovaccine against Leishmania Parasite: Elicitation of Cellular Immune Responses
  20. 3980
    por Walkinshaw, Malcolm
    Publicado 2014
    “…The need for an effective oral therapy for leishmaniasis is addressed through the study of the target N-myristoyltransferase from Leishmania major.…”
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    Multiple chemical scaffolds inhibit a promising Leishmania drug target
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