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  1. 4121
    “…Sand flies are responsible for the transmission of leishmaniasis, a neglected tropical disease claiming more than 50,000 lives annually. …”
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    A climate-driven and field data-assimilated population dynamics model of sand flies
  2. 4122
    “…The aim of the present work was to examine the use of cytokine release assays in the detection of asymptomatic immune responders to Leishmania among HIV+ patients with no previous leishmaniasis or current symptomatology. Eighty two HIV+ patients (all from Fuenlabrada, Madrid, Spain, where a leishmaniasis outbreak occurred in 2009) were examined for Leishmania infantum infection using molecular and humoral response-based methods. …”
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    Asymptomatic immune responders to Leishmania among HIV positive patients
  3. 4123
    “…Current treatment of cutaneous leishmaniasis includes pentavalent antimonials as first-line drugs, but this therapy has shown severe adverse effects. …”
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    The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishmania) amazonensis
  4. 4124
    “…Also, niosomal form of this combination was safe and demonstrated strong anti-leishmaniasis effects highlights further therapeutic approaches against anthroponotic cutaneous leishmaniasis in future planning.…”
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    Antileishmanial Activity of Niosomal Combination Forms of Tioxolone along with Benzoxonium Chloride against Leishmania tropica
  5. 4125
    “…BACKGROUND: Leishmaniasis is an infectious disease caused by an intracellular parasite of Leishmania and is transmitted through the female sandflies bite and may lead to severe skin lesions. …”
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    Evaluation of Different Concentrations of Imatinib on the Viability of Leishmania major: An In Vitro Study
  6. 4126
    “…Visceral Leishmaniasis is a chronic zoonosis and, if left untreated, can be fatal. …”
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    Induction of miR 21 impairs the anti-Leishmania response through inhibition of IL-12 in canine splenic leukocytes
  7. 4127
    “…SIMPLE SUMMARY: The immunopathogenesis of leishmaniasis is not completely understood. Exosomes are extracellular vesicles produced by most eukaryotic cells, containing various molecular constituents with biological effects (e.g., proteins, peptides, RNA). …”
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    Expression of Serum Exosomal miRNA 122 and Lipoprotein Levels in Dogs Naturally Infected by Leishmania infantum: A Preliminary Study
  8. 4128
    “…The parasite Leishmania major, which is responsible for leishmaniasis, expresses two class I FH isoforms: mitochondrial LmFH-1 and cytosolic LmFH-2. …”
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    Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from Leishmania major
  9. 4129
    “…OBJECTIVE: Leishmaniasis is caused by members of the Leishmania species and constitute a group of infective diseases that range from cutaneous lesions to lethal visceral forms. …”
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    Cytokine Gene Expression Alterations in Human Macrophages Infected by Leishmania major
  10. 4130
    “…Public health policies should target neglected diseases such as cutaneous leishmaniasis, tungiasis, scabies, and envenomations. …”
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    Spectrum of skin diseases in Amerindian villages of the Upper Oyapock, French Guiana
  11. 4131
    “…The protozoan parasite Leishmania donovani (L. donovani) causes visceral leishmaniasis, a chronic infection which is fatal when untreated. …”
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    Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts
  12. 4132
    “…This is particularly evident in the case of American cutaneous leishmaniasis due to the high toxicity of current treatments, parenteral administration, and increasing rate of refractory cases. …”
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    Ethanolic Extract of the Fungus Trichoderma asperelloides Induces Ultrastructural Effects and Death on Leishmania amazonensis
  13. 4133
    “…Current drug therapies for cutaneous leishmaniasis are often difficult to administer and treatment failure is an increasingly common occurrence. …”
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    Efficacy of histamine H1 receptor antagonists azelastine and fexofenadine against cutaneous Leishmania major infection
  14. 4134
    “…OBJECTIVE: Leishmaniasis is of public health problems, especially in endemic areas. …”
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    Intralesional Injection of Mouse Mesenchymal Stem Cells Reduces IL-10 Production and Parasite Burden in L. major Infected BALB/c Mice
  15. 4135
    “…Current therapy for visceral leishmaniasis (VL), compromised by drug resistance, toxicity, and high cost, demands for more effective, safer, and low-cost drugs. …”
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    Genomic and Transcriptomic Analysis for Identification of Genes and Interlinked Pathways Mediating Artemisinin Resistance in Leishmania donovani
  16. 4136
    “…Leishmania infantum infantum (LII) is one of the species that causes visceral leishmaniasis (VL) in the Old World, while L. infantum chagasi (LIC) is present in the New World. …”
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    Comparative analysis of biological aspects of Leishmania infantum strains
  17. 4137
    “…Canine leishmaniasis (CanL) is a zoonotic parasitic disease caused by Leishmania infantum in the Mediterranean area and transmitted by phlebotomine sand fly vectors. …”
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    Seroprevalence and risk factors associated with exposure to Leishmania infantum in dogs, in an endemic Mediterranean region
  18. 4138
    “…[Image: see text] Current chemotherapeutics for leishmaniasis have multiple deficiencies, and there is a need for new safe, efficacious, and affordable medicines. …”
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    Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase
  19. 4139
    “…BACKGROUND: Skin lesions of patients affected by non-ulcerated cutaneous leishmaniasis (NUCL) caused by L. (L.) infantum chagasi are characterized by lymphohistiocytic inflammatory infiltrate associated with epithelioid granuloma and scarce parasitism. …”
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    In situ cellular immune response in non-ulcerated skin lesions due to Leishmania (L.) infantum chagasi infection
  20. 4140
    “…Recently, we conducted countrywide epidemiological studies of leishmaniasis in Ecuador and Peru to reveal prevalent species using PCR-RFLP targeting nDNA, and identified unknown hybrid parasites in these countries together with species reported previously. …”
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    Prevalence of Genetically Complex Leishmania Strains With Hybrid and Mito-Nuclear Discordance
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