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4121por Erguler, Kamil, Pontiki, Irene, Zittis, George, Proestos, Yiannis, Christodoulou, Vasiliki, Tsirigotakis, Nikolaos, Antoniou, Maria, Kasap, Ozge Erisoz, Alten, Bulent, Lelieveld, Jos“…Sand flies are responsible for the transmission of leishmaniasis, a neglected tropical disease claiming more than 50,000 lives annually. …”
Publicado 2019
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4122por Botana, Laura, Ibarra-Meneses, Ana Victoria, Sánchez, Carmen, Castro, Alicia, San Martin, Juan Victor, Molina, Laura, Ruiz-Giardin, Jose Manuel, Carrillo, Eugenia, Moreno, Javier“…The aim of the present work was to examine the use of cytokine release assays in the detection of asymptomatic immune responders to Leishmania among HIV+ patients with no previous leishmaniasis or current symptomatology. Eighty two HIV+ patients (all from Fuenlabrada, Madrid, Spain, where a leishmaniasis outbreak occurred in 2009) were examined for Leishmania infantum infection using molecular and humoral response-based methods. …”
Publicado 2019
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4123por Gonçalves-Oliveira, Luiz Filipe, Souza-Silva, Franklin, de Castro Côrtes, Luzia Monteiro, Veloso, Laura Barral, Santini Pereira, Bernardo Acácio, Cysne-Finkelstein, Lea, Lechuga, Guilherme Curty, Bourguignon, Saulo Cabral, Almeida-Souza, Fernando, da Silva Calabrese, Kátia, Ferreira, Vitor Francisco, Alves, Carlos Roberto“…Current treatment of cutaneous leishmaniasis includes pentavalent antimonials as first-line drugs, but this therapy has shown severe adverse effects. …”
Publicado 2019
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4124por Parizi, Maryam Hakimi, Farajzadeh, Saeedeh, Sharifi, Iraj, Pardakhty, Abbas, Parizi, Mohammad Hossein Daie, Sharifi, Hamid, Salarkia, Ehsan, Hassanzadeh, Saeid“…Also, niosomal form of this combination was safe and demonstrated strong anti-leishmaniasis effects highlights further therapeutic approaches against anthroponotic cutaneous leishmaniasis in future planning.…”
Publicado 2019
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4125por Moslehi, Mohsen, Namdar, Fatemeh, Esmaeilifallah, Mahsa, Hejazi, Seyed Hossein, Sokhanvari, Fatemeh, Siadat, Amir Hossein, Hosseini, Seyed Mohsen, Iraji, Fariba“…BACKGROUND: Leishmaniasis is an infectious disease caused by an intracellular parasite of Leishmania and is transmitted through the female sandflies bite and may lead to severe skin lesions. …”
Publicado 2019
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4126por Melo, Larissa Martins, Bragato, Jaqueline Poleto, Venturin, Gabriela Lovizutto, Rebech, Gabriela Torres, Costa, Sidnei Ferro, Garcia, Leandro Encarnação, Lopes, Flávia Lombardi, Eugênio, Flávia de Rezende, Patto dos Santos, Paulo Sérgio, de Lima, Valéria Marçal Felix“…Visceral Leishmaniasis is a chronic zoonosis and, if left untreated, can be fatal. …”
Publicado 2019
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4127por Loria, Antonio Di, Dattilo, Vincenzo, Santoro, Domenico, Guccione, Jacopo, De Luca, Adriana, Ciaramella, Paolo, Pirozzi, Marinella, Iaccino, Enrico“…SIMPLE SUMMARY: The immunopathogenesis of leishmaniasis is not completely understood. Exosomes are extracellular vesicles produced by most eukaryotic cells, containing various molecular constituents with biological effects (e.g., proteins, peptides, RNA). …”
Publicado 2020
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4128“…The parasite Leishmania major, which is responsible for leishmaniasis, expresses two class I FH isoforms: mitochondrial LmFH-1 and cytosolic LmFH-2. …”
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4129por Kalavi, Khodaberdi, Jorjani, Ogholniaz, Faghihi, Mohammad Ali, Mowla, Seyed Javad“…OBJECTIVE: Leishmaniasis is caused by members of the Leishmania species and constitute a group of infective diseases that range from cutaneous lesions to lethal visceral forms. …”
Publicado 2021
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4130por Malmontet, Thomas, Guarmit, Basma, Gaillet, Melanie, Michaud, Celine, Garceran, Nicolas, Chanlin, Romain, Demar, Magalie, Couppie, Pierre, Blaizot, Romain“…Public health policies should target neglected diseases such as cutaneous leishmaniasis, tungiasis, scabies, and envenomations. …”
Publicado 2020
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4131por Chaparro, Visnu, Leroux, Louis-Philippe, Masvidal, Laia, Lorent, Julie, Graber, Tyson E., Zimmermann, Aude, Arango Duque, Guillermo, Descoteaux, Albert, Alain, Tommy, Larsson, Ola, Jaramillo, Maritza“…The protozoan parasite Leishmania donovani (L. donovani) causes visceral leishmaniasis, a chronic infection which is fatal when untreated. …”
Publicado 2020
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4132por Lopes, Danielle de Sousa, dos Santos, Uener Ribeiro, Dos Anjos, Danielle Oliveira, da Silva Júnior, Lauro José Caires, de Paula, Vanderlúcia Fonseca, Vannier-Santos, Marcos André, Silva-Jardim, Izaltina, Castro-Gomes, Thiago, Pirovani, Carlos Priminho, Lima-Santos, Jane“…This is particularly evident in the case of American cutaneous leishmaniasis due to the high toxicity of current treatments, parenteral administration, and increasing rate of refractory cases. …”
Publicado 2020
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4133“…Current drug therapies for cutaneous leishmaniasis are often difficult to administer and treatment failure is an increasingly common occurrence. …”
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4134“…OBJECTIVE: Leishmaniasis is of public health problems, especially in endemic areas. …”
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4135por Ghosh, Sushmita, Verma, Aditya, Kumar, Vinay, Pradhan, Dibyabhaba, Selvapandiyan, Angamuthu, Salotra, Poonam, Singh, Ruchi“…Current therapy for visceral leishmaniasis (VL), compromised by drug resistance, toxicity, and high cost, demands for more effective, safer, and low-cost drugs. …”
Publicado 2020
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4136por Ferreira-Paes, Taiana, Charret, Karen dos Santos, Ribeiro, Merienny Ramos da Silva, Rodrigues, Raquel Ferreira, Leon, Leonor Laura“…Leishmania infantum infantum (LII) is one of the species that causes visceral leishmaniasis (VL) in the Old World, while L. infantum chagasi (LIC) is present in the New World. …”
Publicado 2020
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4137por Rombolà, Pasquale, Barlozzari, Giulia, Carvelli, Andrea, Scarpulla, Manuela, Iacoponi, Francesca, Macrì, Gladia“…Canine leishmaniasis (CanL) is a zoonotic parasitic disease caused by Leishmania infantum in the Mediterranean area and transmitted by phlebotomine sand fly vectors. …”
Publicado 2021
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4138por Mina, John G. M., Charlton, Rebecca L., Alpizar-Sosa, Edubiel, Escrivani, Douglas O., Brown, Christopher, Alqaisi, Amjed, Borsodi, Maria Paula G., Figueiredo, Claudia P., de Lima, Emanuelle V., Dickie, Emily A., Wei, Wenbin, Coutinho-Silva, Robson, Merritt, Andy, Smith, Terry K., Barrett, Michael P., Rossi-Bergmann, Bartira, Denny, Paul W., Steel, Patrick G.“…[Image: see text] Current chemotherapeutics for leishmaniasis have multiple deficiencies, and there is a need for new safe, efficacious, and affordable medicines. …”
Publicado 2020
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4139por Sandoval, Carmen, Araujo, Gabriela, Sosa, Wilfredo, Avalos, Sara, Silveira, Fernando, Corbett, Carlos, Zúniga, Concepción, Laurenti, Marcia“…BACKGROUND: Skin lesions of patients affected by non-ulcerated cutaneous leishmaniasis (NUCL) caused by L. (L.) infantum chagasi are characterized by lymphohistiocytic inflammatory infiltrate associated with epithelioid granuloma and scarce parasitism. …”
Publicado 2021
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4140por Kato, Hirotomo, Cáceres, Abraham G., Gomez, Eduardo A., Tabbabi, Ahmed, Mizushima, Daiki, Yamamoto, Daisuke S., Hashiguchi, Yoshihisa“…Recently, we conducted countrywide epidemiological studies of leishmaniasis in Ecuador and Peru to reveal prevalent species using PCR-RFLP targeting nDNA, and identified unknown hybrid parasites in these countries together with species reported previously. …”
Publicado 2021
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