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  1. 4321
    “…Unfortunately, in recent years an increasing number of autochthonous canine and human visceral leishmaniasis (VL) cases have been reported. The parasite is Leishmania (Leishmania) infantum and it is transmitted by sand flies (Phlebotominae). …”
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    Hidden danger: Unexpected scenario in the vector-parasite dynamics of leishmaniases in the Brazil side of triple border (Argentina, Brazil and Paraguay)
  2. 4322
    “…Antimonials (Sb) were used for decades for chemotherapy of visceral leishmaniasis (VL). Now abandoned in the Indian subcontinent (ISC) because of Leishmania donovani resistance, this drug offers a unique model for understanding drug resistance dynamics. …”
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    Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent
  3. 4323
    “…Parasites enter a variety of host cells, although a majority are found in macrophages where they replicate intracellularly during chronic leishmaniasis. Symptomatic leishmaniasis causes considerable human morbidity in endemic regions. …”
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    Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes
  4. 4324
    “…BACKGROUND: Visceral leishmaniasis (VL) caused by Leishmania infantum is an ongoing health problem in southern Europe, where dogs are considered the main reservoirs of the disease. …”
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    Multilocus microsatellite typing (MLMT) reveals host-related population structure in Leishmania infantum from northeastern Italy
  5. 4325
    “…There is no safe and efficacious vaccine against human leishmaniasis available and live attenuated vaccines have been used as a prophylactic alternative against the disease. …”
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    Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice
  6. 4326
    “…Recently, necroptosis has emerged as a key component of resistance against pathogens including infected macrophage by Leishmania infantum, the ethiologic agent of Visceral leishmaniasis (VL). VL is the most severe form of Leishmaniasis, characterized by systemic inflammation and neutropenia. …”
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    RIPK1–RIPK3–MLKL-Associated Necroptosis Drives Leishmania infantum Killing in Neutrophils
  7. 4327
    “…Also, it informs which protein families are unique and conserved within taxon for the choice of taxon-specific biomarkers of vector exposure, as well as those families more conserved across taxa to be used as pan-specific vaccines for leishmaniasis.…”
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    Comparative Evolution of Sand Fly Salivary Protein Families and Implications for Biomarkers of Vector Exposure and Salivary Vaccine Candidates
  8. 4328
    “…BACKGROUND: Leishmania donovani is a protozoan parasite, a primary causative agent of visceral leishmaniasis. Sterol produced via the mevalonate pathway, show differences in composition across biological kingdoms. …”
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    A Plant like Cytochrome P450 Subfamily CYP710C1 Gene in Leishmania donovani Encodes Sterol C-22 Desaturase and its Over-expression Leads to Resistance to Amphotericin B
  9. 4329
    “…Leishmaniasis is a complex of neglected diseases caused by parasites of the genus Leishmania, such as Leishmania (Leishmania) amazonensis, the ethiologic agent of diffuse cutaneous leishmaniasis in Brazil. …”
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    Characterization of Sv129 Mice as a Susceptible Model to Leishmania amazonensis
  10. 4330
    “…Here, we describe the hepatic alterations observed in dogs with differing clinical manifestations of visceral leishmaniasis in an endemic area in the state of Bahia, Brazil. …”
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    Assessment of histological liver alterations in dogs naturally infected with Leishmania infantum
  11. 4331
    “…The following incidence rates were mapped: dengue, acute Chagas disease, schistosomiasis, Hansen's disease, hepatitis A, cutaneous leishmaniasis, visceral leishmaniasis, leptospirosis, malaria, and tuberculosis. …”
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    Doenças infecciosas e parasitárias no Brasil de 2010 a 2017: aspectos para vigilância em saúde
  12. 4332
    “…Background: A safe and effective vaccine against human leishmaniasis still requires the identification of better antigens for immunization and adequate models to evaluate the immune response. …”
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    Immunogenicity of Potential CD4(+) and CD8(+) T Cell Epitopes Derived From the Proteome of Leishmania braziliensis
  13. 4333
    “…OBJECTIVE: Leishmaniasis is caused by different Leishmania spp. …”
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    Relationship of Leishmania RNA Virus (LRV) and treatment failure in clinical isolates of Leishmania major
  14. 4334
    “…Overall in Turkey, 7794 cutaneous leishmaniasis have been reported. IMPLICATIONS: Since the influx of Syrian refugees, there has been an increase in cases of leishmaniasis and measles. …”
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    Profiling infectious diseases in Turkey after the influx of 3.5 million Syrian refugees
  15. 4335
    “…BACKGROUND: The Greek island of Crete is endemic for both visceral leishmaniasis (VL) and recently increasing cutaneous leishmaniasis (CL). …”
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    Sand fly fauna of Crete and the description of Phlebotomus (Adlerius) creticus n. sp. (Diptera: Psychodidae)
  16. 4336
    “…BACKGROUND: Leishmaniasis is a serious multifactorial parasitic disease with limited treatment options. …”
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    Total Phenolic Fraction (TPF) from Extra Virgin Olive Oil: Induction of apoptotic-like cell death in Leishmania spp. promastigotes and in vivo potential of therapeutic immunomodulation
  17. 4337
    “…BACKGROUND: In Mali, cutaneous leishmaniasis (CL) and filariasis are co-endemic. Previous studies in animal models of infection have shown that sand fly saliva enhance infectivity of Leishmania parasites in naïve hosts while saliva-specific adaptive immune responses may protect against cutaneous and visceral leishmaniasis. …”
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    Individuals co-exposed to sand fly saliva and filarial parasites exhibit altered monocyte function
  18. 4338
    “…ABSTRACT: Diseases caused by trypanosomatids (Sleeping sickness, Chagas disease, and leishmaniasis) are a serious public health concern in low-income endemic countries. …”
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    Reproduction in Trypanosomatids: Past and Present
  19. 4339
    “…Neutrophils play an important role in the outcome of leishmaniasis, contributing either to exacerbating or controlling the progression of infection, a dual effect whose underlying mechanisms are not clear. …”
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    Leishmania Parasites Drive PD-L1 Expression in Mice and Human Neutrophils With Suppressor Capacity
  20. 4340
    “…Pathophysiology of visceral leishmaniasis (VL) is not fully understood and it has been widely accepted that the parasitic components and host immune response both contribute to the perpetuation of the disease. …”
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    Tissue/Biofluid Specific Molecular Cartography of Leishmania donovani Infected BALB/c Mice: Deciphering Systemic Reprogramming
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