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4761por Al-Khalaifah, Hanan S.“…Leishmaniasis is a major health problem with 600k - 1M new cases worldwide and 1 billion at risk. …”
Publicado 2022
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4762por Zabala-Peñafiel, Anabel, Fantinatti, Maria, Dias-Lopes, Geovane, da Silva, Jéssica Leite, Miranda, Luciana de Freitas Campos, Lyra, Marcelo Rosandiski, Pimentel, Maria Inês Fernandes, Conceição-Silva, Fátima, Alves, Carlos Roberto“…FINDINGS: LRV1 was detected in three clinical isolates which was phylogenetically related to other sequences reported from other American tegumentary leishmaniasis (ATL) endemic areas of Brazil. Patients infected with L. …”
Publicado 2022
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4763“…Leishmaniasis control often relies upon insecticidal control of phlebotomine sandfly vector populations. …”
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4764“…In this review we will discuss about origin of sex and different strategies of evolve sexual reproduction in some protists such that cause human diseases like malaria, toxoplasmosis, sleeping sickness, Chagas disease, and leishmaniasis.…”
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4765“…The use of liposomal amphotericin B formulation is referenced in many international guidelines for the treatment of fungal infections such as Aspergillus and cryptococcal disease and Candida infections, as well as other less common infections such as visceral leishmaniasis. With the development of liposomal amphotericin B, an improved therapeutic index could be achieved that allowed the attainment of higher drug concentrations in both the plasma and tissue while simultaneously lowering the toxicity compared with amphotericin B deoxycholate. …”
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4766por Esteves, Sofia, Costa, Inês, Luelmo, Sara, Santarém, Nuno, Cordeiro-da-Silva, Anabela“…Leishmaniasis, a vector-borne parasitic protozoan disease, is among the most important neglected tropical diseases. …”
Publicado 2022
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4767“…In recent years, zinc supplementation has been widely used for various skin conditions, including infectious diseases (viral warts, genital herpes, cutaneous leishmaniasis, leprosy), inflammatory diseases (hidradenitis suppurativa, acne vulgaris, rosacea, eczematous dermatitis, seborrheic dermatitis, psoriasis, Behcet's disease, oral lichen planus), pigmentary diseases (vitiligo, melasma), tumor-associated diseases (basal cell carcinoma), endocrine and metabolic diseases (necrolytic migratory erythema, necrolytic acral erythema), hair diseases (alopecia), and so on. …”
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4768por Chowdhury, Rajib, Faria, Shyla, Huda, M. Mamun, Chowdhury, Vashkar, Maheswary, Narayan Prosad, Mondal, Dinesh, Akhter, Shireen, Akter, Sakila, Khan, Rajaul Karim, Nabi, Shah Golam, Kroeger, Axel, Argaw, Daniel, Alvar, Jorge, Dash, Aditya Prasad, Banu, Qamar“…BACKGROUND: A number of studies on visceral leishmaniasis (VL) vector control have been conducted during the past decade, sometimes came to very different conclusion. …”
Publicado 2017
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4769por de Jesus, Matheus Silva, Cruz, João Victor Andrade, Coelho, Lívia Brito, Borja, Lairton Souza, da Silva, Edmilson Domingos, Solcà, Manuela da Silva, Brodskyn, Claudia Ida, Fraga, Deborah Bittencourt Mothé“…BACKGROUND: Visceral leishmaniasis (VL) is a zoonotic disease caused by Leishmania infantum, for which dogs constitute the main urban parasite reservoir. …”
Publicado 2021
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4770por Mendes, Artur Augusto Velho, Filgueira, Camila Patrício Braga, Miranda, Luciana de Freitas Campos, de Almeida, Adilson Benedito, Cantanhêde, Lilian Motta, Fagundes, Aline, Pereira, Sandro Antônio, Menezes, Rodrigo Caldas, Cupolillo, Elisa“…OBJECTIVES: Identify the Leishmania species causing cutaneous leishmaniasis in a mare, living in Rio de Janeiro State (Brazil), and search the presence of Leishmania viruses in the isolated parasite. …”
Publicado 2023
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4771por Kesper, Norival, Ignácio Junior, Jose Carlos, Rocci, Rafael Avila, Cunha, Mirela A., Lindoso, José Angelo Lauletta“…Serological tests for detecting CD use total antigen, which present cross reactivity with other endemic diseases, such as leishmaniasis. It is urge the use of a specific test to determinate the real prevalence of T. cruzi infection in people living with HIV AIDS (PLWHA). …”
Publicado 2023
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4772“…We emphasized here their evolutionary uniqueness and conservation and discussed their potential implications for parasite biology with regards to future therapeutic targets against visceral leishmaniasis.…”
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4773por Santana, Mayara Cristhine de Oliveira, Chourabi, Khaled, Cantanhêde, Lilian Motta, Cupolillo, Elisa“…A relevant aspect in the epidemiology of Tegumentary Leishmaniasis (TL) are the Leishmania parasites carrying a viral endosymbiont, Leishmania RNA Virus 1 (LRV1), a dsRNA virus. …”
Publicado 2023
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4774por Sacramento, Laís Amorim, Amorim, Camila Farias, Lombana, Claudia G., Beiting, Daniel, Novais, Fernanda, Carvalho, Lucas P., Carvalho, Edgar M., Scott, Phillip“…Cytolytic CD8(+) T cells mediate immunopathology in cutaneous leishmaniasis without controlling parasites. Here, we identify factors involved in CD8(+) T cell migration to the lesion that could be targeted to ameliorate disease severity. …”
Publicado 2023
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4775por Challapa-Mamani, Mabel R., Tomás-Alvarado, Eduardo, Espinoza-Baigorria, Angela, León-Figueroa, Darwin A., Sah, Ranjit, Rodriguez-Morales, Alfonso J., Barboza, Joshuan J.“…Leishmaniasis, a disease caused by Leishmania parasites and transmitted via sandflies, presents in two main forms: cutaneous and visceral, the latter being more severe. …”
Publicado 2023
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4776“…The model suggests that different parasite determinants may be targeted by different strategies to achieve more effective control of leishmaniasis and other similar diseases.…”
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4777por Habtemariam, Solomon“…Since andrographolide and other structurally related diterpenes were shown to have antileishmanial activity, the aim of the present study was to assess the in vitro effect of premna diterpenes against Leishmania aethiopica; the causative agent of cutaneous leishmaniasis in Ethiopia. RESULTS: The diterpenes showed potent concentration-dependant suppressive effect on the viability of axenically cultured amastigotes of L. aethiopica. …”
Publicado 2003
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4778Publicado 1981“…The promastigote form of Leishmania donovani and Leishmania tropica, the etiologic agents of visceral and cutaneous leishmaniasis, respectively, readily parasitize unstimulated J774G8 macrophage-like cells, whereas 80-95% of the same promastigotes are killed within resident macrophages from normal BALB/c mice. …”
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4779por Lohoff, Michael, Duncan, Gordon S., Ferrick, David, Mittrücker, Hans-Willi, Bischof, Susi, Prechtl, Stefan, Röllinghoff, Martin, Schmitt, Edgar, Pahl, Andreas, Mak, Tak W.“…We have used experimental leishmaniasis to show that, like IRF-1(−/)− mice, IRF-2(−/)− mice are susceptible to Leishmania major infection due to a defect in Th1 differentiation. …”
Publicado 2000
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4780por Chavali, Arvind K, Whittemore, Jeffrey D, Eddy, James A, Williams, Kyle T, Papin, Jason A“…We have reconstructed the metabolic network of Leishmania major, a poorly characterized organism that causes cutaneous leishmaniasis in mammalian hosts. This network reconstruction accounts for 560 genes, 1112 reactions, 1101 metabolites and 8 unique subcellular localizations. …”
Publicado 2008
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